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Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

Cell, 2012-12, Vol.151 (7), p.1557-1568

2012

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An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

Blood, 2010-02, Vol.115 (8), p.1640-1649

2010

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Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain

Haematologica (Roma), 2011-11, Vol.96 (11), p.1670-1677

2011

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The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells

Blood, 2012-04, Vol.119 (16), p.3828-3835

2012

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Binding Mode Prediction of Cytochrome P450 and Thymidine Kinase Protein−Ligand Complexes by Consideration of Water and Rescoring in Automated Docking

Journal of medicinal chemistry, 2005-04, Vol.48 (7), p.2308-2318

2005

Volltextzugriff (PDF)

721 AT1412, a patient-derived CD9 antibody in preclinical development promoting tumor immune infiltration and inducing tumor rejection

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A431-A432

2020

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Molecular mechanisms for contribution of MHC molecules to autoimmune diseases

Current opinion in immunology, 2014-12, Vol.31, p.24-30

2014

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Mechanisms of peptide repertoire selection by HLA-DM

Trends in immunology, 2013-10, Vol.34 (10), p.495-501

2013

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In vivo discovery of immunotherapy targets in the tumour microenvironment

Nature (London), 2014-02, Vol.506 (7486), p.52-57

2014

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The role of MHC class II polymorphisms for DM-mediated peptide editing and autoimmunity

The Journal of immunology (1950), 2017-05, Vol.198 (1_Supplement), p.156-156.24

2017

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Abstract 532: A patient-derived anti-CD9 antibody induces tumor rejection and synergistically enhances anti-PD1 activity

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.532-532

2020

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Preclinical Development of AT1412, a Patient Derived CD9 Antibody That Does Not Induce Thrombosis for Treatment of B ALL

Blood, 2020-11, Vol.136 (Supplement 1), p.41-42

2020

Volltextzugriff (PDF)

Abstract 531: AT1412, a patient-derived antibody in development for the treatment of CD9-positive precursor B-acute lymphoblastic leukemia

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.531-531

2020

Volltextzugriff (PDF)

Abstract LB-200: A patient derived antibody targeting the tetraspanin CD9 synergistically inhibits tumor growth with an anti PD1 antibody

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.LB-200-LB-200

2017

Volltextzugriff (PDF)

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Blood, 2019-11, Vol.134 (Supplement_1), p.4461-4461

2019

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Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F

Life science alliance, 2020-11, Vol.3 (11), p.e202000883

2020

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IgG Antibodies Directed towards a Single Antigenic Surface In the Spacer Domain of ADAMTS13 Predominate In Plasma of Patients with Acquired TTP

Blood, 2010-11, Vol.116 (21), p.1438-1438

2010

Volltextzugriff (PDF)

Crystal Structure of the HLA-DMaHLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

Cell, 2012-12, Vol.151 (7), p.1557-1568

2012

Volltextzugriff (PDF)

The macrophage mannose receptor promotes uptake of ADAMTS 13 by dendritic cells

Blood, 2012, Vol.119 (16), p.3828-3835

2012

Volltextzugriff (PDF)

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS 13 spacer domain identifies a binding site for the A2 domain of VWF

Blood, 2010, Vol.115 (8), p.1640-1649

2010

Volltextzugriff (PDF)

C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB111 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells

Blood, 2011-11, Vol.118 (21), p.196-196

2011

Volltextzugriff (PDF)

Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP

Thrombosis and haemostasis, 2006-09, Vol.96 (3), p.295

2006

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Critical Amino Acids in a Conserved Region of the Spacer Domain Contributing to the Binding of Anti-ADAMTS13 Antibodies

Blood, 2008-11, Vol.112 (11), p.275-275

2008

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Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes

Blood, 2007-11, Vol.110 (11), p.2158-2158

2007

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Beta2-Glycoprotein I: Implications for a Regulatory Role in Thrombotic Thrombocytopenic Purpura

Blood, 2007-11, Vol.110 (11), p.278-278

2007

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Crystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF

Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain

The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells

Binding Mode Prediction of Cytochrome P450 and Thymidine Kinase Protein−Ligand Complexes by Consideration of Water and Rescoring in Automated Docking

721 AT1412, a patient-derived CD9 antibody in preclinical development promoting tumor immune infiltration and inducing tumor rejection

Molecular mechanisms for contribution of MHC molecules to autoimmune diseases

Mechanisms of peptide repertoire selection by HLA-DM

In vivo discovery of immunotherapy targets in the tumour microenvironment

The role of MHC class II polymorphisms for DM-mediated peptide editing and autoimmunity

Abstract 532: A patient-derived anti-CD9 antibody induces tumor rejection and synergistically enhances anti-PD1 activity

Preclinical Development of AT1412, a Patient Derived CD9 Antibody That Does Not Induce Thrombosis for Treatment of B ALL

Abstract 531: AT1412, a patient-derived antibody in development for the treatment of CD9-positive precursor B-acute lymphoblastic leukemia

Abstract LB-200: A patient derived antibody targeting the tetraspanin CD9 synergistically inhibits tumor growth with an anti PD1 antibody

AT1412, a Patient-Derived Antibody in Development for the Treatment of CD9 Positive Precursor B-Acute Lymphoblastic Leukemia

Implications for tetraspanin-enriched microdomain assembly based on structures of CD9 with EWI-F

IgG Antibodies Directed towards a Single Antigenic Surface In the Spacer Domain of ADAMTS13 Predominate In Plasma of Patients with Acquired TTP

Crystal Structure of the HLA-DMaHLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection

The macrophage mannose receptor promotes uptake of ADAMTS 13 by dendritic cells

An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS 13 spacer domain identifies a binding site for the A2 domain of VWF

C-Type Lectin Receptor Mediated Immune Recognition of ADAMTS13 Promotes HLA-DRB111 Dependent Presentation of CUB1-2 Derived Peptides by Dendritic Cells

Amino acid regions 572-579 and 657-666 of the spacer domain of ADAMTS13 provide a common antigenic core required for binding of antibodies in patients with acquired TTP

Critical Amino Acids in a Conserved Region of the Spacer Domain Contributing to the Binding of Anti-ADAMTS13 Antibodies

Human Antibodies with Specificity for the Spacer Domain of ADAMTS13 Are Derived from VH1-69 Germline Genes

Beta2-Glycoprotein I: Implications for a Regulatory Role in Thrombotic Thrombocytopenic Purpura

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