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In Vitro Rat Hepatic and Intestinal Metabolism of the Organophosphate Pesticides Chlorpyrifos and Diazinon

Toxicological sciences, 2003-04, Vol.72 (2), p.193-200

2003

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Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Organophosphorus Pesticide Diazinon

Neurotoxicology (Park Forest South), 2004-12, Vol.25 (6), p.1013-1030

2004

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Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos

Toxicology (Amsterdam), 2006-03, Vol.220 (1), p.13-25

2006

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Comparison of Chlorpyrifos-Oxon and Paraoxon Acetylcholinesterase Inhibition Dynamics: Potential Role of a Peripheral Binding Site

Toxicological sciences, 2004-08, Vol.80 (2), p.239-248

2004

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Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: A potential biomonitoring matrix

Toxicology (Amsterdam), 2003-06, Vol.188 (2), p.219-232

2003

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Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model

Toxicology letters, 2002-09, Vol.135 (1), p.51-59

2002

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Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat

Toxicology and applied pharmacology, 2005-05, Vol.205 (1), p.31-42

2005

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Impact of Repeated Nicotine and Alcohol Coexposure on in Vitro and in Vivo Chlorpyrifos Dosimetry and Cholinesterase Inhibition

Journal of Toxicology and Environmental Health, Part A, 2011-01, Vol.74 (20), p.1334-1350

2011

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Using physiologically based pharmacokinetic modeling and benchmark dose methods to derive an occupational exposure limit for N-methylpyrrolidone

Regulatory toxicology and pharmacology, 2016-04, Vol.76, p.102-112

2016

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Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding

Toxicology (Amsterdam), 2015-07, Vol.333, p.1-13

2015

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Determination of age and gender differences in biochemical processes affecting the disposition of 2-butoxyethanol and its metabolites in mice and rats to improve PBPK modeling

Toxicology letters, 2005-03, Vol.156 (1), p.127-161

2005

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Derivation of a Human Equivalent Concentration for n-Butanol Using A Physiologically Based Pharmacokinetic Model for n-Butyl Acetate and Metabolites n-Butanol and n-Butyric Acid

Toxicological sciences, 2005-05, Vol.85 (1), p.429-446

2005

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Methyl isobutyl ketone exposure-related increases in specific measures of alpha 2u-globulin ( alpha 2u) nephropathy in male rats along with in vitro evidence of reversible protein binding

Toxicology (Amsterdam), 2015-07, Vol.333, p.1-13

2015

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Assessing dermal absorption

Toxicological sciences, 2000-11, Vol.58 (1), p.1-2

POET, Torka S

2000

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Assessment of the percutaneous absorption of trichloroethylene in rats and humans using MS/MS real-time breath analysis and physiologically based pharmacokinetic modeling

Toxicological sciences, 2000-07, Vol.56 (1), p.61-72

2000

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COMPARATIVE METABOLISM OF CARBON TETRACHLORIDE IN RATS, MICE, AND HAMSTERS USING GAS UPTAKE AND PBPK MODELING

Journal of Toxicology and Environmental Health, Part A, 2000-08, Vol.60 (8), p.531-548

2000

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Utility of Real Time Breath Analysis and Physiologically Based Pharmacokinetic Modeling to Determine the Percutaneous Absorption of Methyl Chloroform in Rats and Humans

Toxicological sciences, 2000-03, Vol.54 (1), p.42-51

2000

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Mode of Action and Pharmacokinetic Studies of 2-Butoxyethanol in the Mouse with an Emphasis on Forestomach Dosimetry

Toxicological sciences, 2003-02, Vol.71 (2), p.176-189

2003

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PBPK Modeling of the Percutaneous Absorption of Perchloroethylene from a Soil Matrix in Rats and Humans

Toxicological sciences, 2002-05, Vol.67 (1), p.17-31

2002

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Participation of cytochromes P4502B and P4503A in cocaine toxicity in rat hepatocytes

Drug metabolism and disposition, 1996-01, Vol.24 (1), p.74

1996

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DETERMINATION OF BIOKINETIC INTERACTIONS IN CHEMICAL MIXTURES USING REAL-TIME BREATH ANALYSIS AND PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING

Journal of Toxicology and Environmental Health, Part A, 2000-04, Vol.59 (8), p.653-670

2000

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In vitro uptake of methyl tert-butyl ether in male rat kidney : Use of a two-compartment model to describe protein interactions

Toxicology and applied pharmacology, 1997-08, Vol.145 (2), p.340-348

1997

Volltextzugriff (PDF)

Effects of Nicotine Exposure on In Vitro Metabolism of Chlorpyrifos in Male Sprague-Dawley Rats

Journal of Toxicology and Environmental Health, Part A, 2009-01, Vol.72 (2), p.74-82

2009

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Pharmacokinetics of tertiary butyl alcohol in male and female Fischer 344 rats

Toxicology letters, 1997-08, Vol.92 (3), p.179-186

1997

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Inactivation of Cytochromes P450 2B Protects Against Cocaine-Mediated Toxicity in Rat Liver Slices

Toxicology and applied pharmacology, 1994-05, Vol.126 (1), p.26-32

1994

Volltextzugriff (PDF)

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In Vitro Rat Hepatic and Intestinal Metabolism of the Organophosphate Pesticides Chlorpyrifos and Diazinon

Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Organophosphorus Pesticide Diazinon

Age-dependent pharmacokinetic and pharmacodynamic response in preweanling rats following oral exposure to the organophosphorus insecticide chlorpyrifos

Comparison of Chlorpyrifos-Oxon and Paraoxon Acetylcholinesterase Inhibition Dynamics: Potential Role of a Peripheral Binding Site

Characterization of the in vitro kinetic interaction of chlorpyrifos-oxon with rat salivary cholinesterase: A potential biomonitoring matrix

Monte Carlo analysis of the human chlorpyrifos-oxonase (PON1) polymorphism using a physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model

Pharmacokinetic and pharmacodynamic interaction for a binary mixture of chlorpyrifos and diazinon in the rat

Impact of Repeated Nicotine and Alcohol Coexposure on in Vitro and in Vivo Chlorpyrifos Dosimetry and Cholinesterase Inhibition

Using physiologically based pharmacokinetic modeling and benchmark dose methods to derive an occupational exposure limit for N-methylpyrrolidone

Methyl isobutyl ketone exposure-related increases in specific measures of α2u-globulin (α2u) nephropathy in male rats along with in vitro evidence of reversible protein binding

Determination of age and gender differences in biochemical processes affecting the disposition of 2-butoxyethanol and its metabolites in mice and rats to improve PBPK modeling

Derivation of a Human Equivalent Concentration for n-Butanol Using A Physiologically Based Pharmacokinetic Model for n-Butyl Acetate and Metabolites n-Butanol and n-Butyric Acid

Methyl isobutyl ketone exposure-related increases in specific measures of alpha 2u-globulin ( alpha 2u) nephropathy in male rats along with in vitro evidence of reversible protein binding

Assessing dermal absorption

Assessment of the percutaneous absorption of trichloroethylene in rats and humans using MS/MS real-time breath analysis and physiologically based pharmacokinetic modeling

COMPARATIVE METABOLISM OF CARBON TETRACHLORIDE IN RATS, MICE, AND HAMSTERS USING GAS UPTAKE AND PBPK MODELING

Utility of Real Time Breath Analysis and Physiologically Based Pharmacokinetic Modeling to Determine the Percutaneous Absorption of Methyl Chloroform in Rats and Humans

Mode of Action and Pharmacokinetic Studies of 2-Butoxyethanol in the Mouse with an Emphasis on Forestomach Dosimetry

PBPK Modeling of the Percutaneous Absorption of Perchloroethylene from a Soil Matrix in Rats and Humans

Participation of cytochromes P4502B and P4503A in cocaine toxicity in rat hepatocytes

DETERMINATION OF BIOKINETIC INTERACTIONS IN CHEMICAL MIXTURES USING REAL-TIME BREATH ANALYSIS AND PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING

In vitro uptake of methyl tert-butyl ether in male rat kidney : Use of a two-compartment model to describe protein interactions

Effects of Nicotine Exposure on In Vitro Metabolism of Chlorpyrifos in Male Sprague-Dawley Rats

Pharmacokinetics of tertiary butyl alcohol in male and female Fischer 344 rats

Inactivation of Cytochromes P450 2B Protects Against Cocaine-Mediated Toxicity in Rat Liver Slices

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