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First FDA Approval of Dual Anti-HER2 Regimen: Pertuzumab in Combination with Trastuzumab and Docetaxel for HER2-Positive Metastatic Breast Cancer

Clinical cancer research, 2013-09, Vol.19 (18), p.4911-4916

2013

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U.S. Food and Drug Administration Approval: Panitumumab for Epidermal Growth Factor Receptor–Expressing Metastatic Colorectal Carcinoma with Progression Following Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Containing Chemotherapy Regimens

Clinical cancer research, 2008-03, Vol.14 (5), p.1296-1302

2008

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ICH Guidelines: Inception, Revision, and Implications for Drug Development

Toxicological sciences, 2010-12, Vol.118 (2), p.356-367

2010

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Safety Assessment of Biotechnology-Derived Pharmaceuticals: ICH and Beyond

Toxicologic pathology, 1999-01, Vol.27 (1), p.27-31

1999

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U.S. Food and Drug Administration Approval: Ofatumumab for the Treatment of Patients with Chronic Lymphocytic Leukemia Refractory to Fludarabine and Alemtuzumab

Clinical cancer research, 2010-09, Vol.16 (17), p.4331-4338

2010

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Preclinical Development Strategies for Novel Gene Therapeutic Products

Toxicologic pathology, 1999-01, Vol.27 (1), p.4-7

1999

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Eribulin Mesylate for the Treatment of Patients with Refractory Metastatic Breast Cancer: Use of a Physician's Choice Control Arm in a Randomized Approval Trial

Clinical cancer research, 2012-03, Vol.18 (6), p.1496-1505

2012

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Clinical infection control in gene therapy: a multidisciplinary conference

Infection control and hospital epidemiology, 2000-10, Vol.21 (10), p.659-673

2000

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A method for obtaining and culturing large numbers of purified organ-derived murine endothelial cells

Journal of leukocyte biology, 1994-04, Vol.55 (4), p.467-475

1994

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Nonclinical Toxicology in Support of Licensure of Gene Therapies

Molecular therapy, 2003-07, Vol.8 (1), p.8-10

2003

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Functional and biochemical properties of rat Kupffer cells and peritoneal macrophages

Journal of leukocyte biology, 1988-08, Vol.44 (2), p.71-78

1988

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Nonclinical Toxicology in Support of Licensure of Gene Therapies: Arlington, VA, USA, March 13-14, 2003

Molecular therapy, 2003-07, Vol.8 (1), p.8-10

2003

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Activation of liver macrophages following phenobarbital treatment of rats

Hepatology (Baltimore, Md.), 1988-09, Vol.8 (5), p.1051-1055

1988

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ROD-CORED VESICLES IN LARGE GRANULAR LYMPHOCYTE (LGL) LEUKEMIA CELLS OF RATS: ALTERATIONS INDUCED FOLLOWING METASTASIS TO THE LIVER

Biomedical Research, 1996/02/01, Vol.17(1), pp.53-65

1996

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Potential role of activated macrophages in acetaminophen hepatotoxicity: I. Isolation and characterization of activated macrophages from rat liver

Toxicology and applied pharmacology, 1986, Vol.86 (2), p.204-215

1986

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FDA comments on phase I clinical trials without vector biodistribution data

Nature genetics, 1999-08, Vol.22 (4), p.326-326

1999

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TNF-alpha is a principal cytokine involved in the recruitment of NK cells to liver parenchyma

The Journal of immunology (1950), 1994-07, Vol.153 (1), p.333-342

1994

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Potential role of activated macrophages in acetaminophen hepatotoxicity: II. Mechanism of macrophage accumulation and activation

Toxicology and applied pharmacology, 1986, Vol.86 (2), p.216-226

1986

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Potential role of activated macrophages in acetaminophen hepatotoxicity

Toxicology and applied pharmacology, 1986-11, Vol.86 (2), p.204-215

1986

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Potential role of activated macrophages in acetaminophen hepatotoxicity

Toxicology and applied pharmacology, 1986-11, Vol.86 (2), p.216-226

1986

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c-Ets-1 protein is hyperphosphorylated during mitosis

Oncogene, 1993-03, Vol.8 (3), p.771-780

1993

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Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia

The Journal of immunology (1950), 1994-03, Vol.152 (5), p.2289-2297

1994

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Quantitative analysis of rod-cored vesicles and dense granules of large granular lymphocytes in the liver, spleen, and peripheral blood of rats

Cell and tissue research, 1994-04, Vol.276 (1), p.187-195

1994

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Substrate-specific proteases (BLT-esterase) are localized predominantly in the natural killer cells of unprimed mice

Journal of leukocyte biology, 1993-04, Vol.53 (4), p.454-461

1993

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An improved in vitro assay to quantitate chemotaxis of rat peripheral blood large granular lymphocytes (LGL)

Journal of immunological methods, 1990-12, Vol.135 (1), p.213-223

1990

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First FDA Approval of Dual Anti-HER2 Regimen: Pertuzumab in Combination with Trastuzumab and Docetaxel for HER2-Positive Metastatic Breast Cancer

U.S. Food and Drug Administration Approval: Panitumumab for Epidermal Growth Factor Receptor–Expressing Metastatic Colorectal Carcinoma with Progression Following Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Containing Chemotherapy Regimens

ICH Guidelines: Inception, Revision, and Implications for Drug Development

Safety Assessment of Biotechnology-Derived Pharmaceuticals: ICH and Beyond

U.S. Food and Drug Administration Approval: Ofatumumab for the Treatment of Patients with Chronic Lymphocytic Leukemia Refractory to Fludarabine and Alemtuzumab

Preclinical Development Strategies for Novel Gene Therapeutic Products

Eribulin Mesylate for the Treatment of Patients with Refractory Metastatic Breast Cancer: Use of a Physician's Choice Control Arm in a Randomized Approval Trial

Clinical infection control in gene therapy: a multidisciplinary conference

A method for obtaining and culturing large numbers of purified organ-derived murine endothelial cells

Nonclinical Toxicology in Support of Licensure of Gene Therapies

Functional and biochemical properties of rat Kupffer cells and peritoneal macrophages

Nonclinical Toxicology in Support of Licensure of Gene Therapies: Arlington, VA, USA, March 13-14, 2003

Activation of liver macrophages following phenobarbital treatment of rats

ROD-CORED VESICLES IN LARGE GRANULAR LYMPHOCYTE (LGL) LEUKEMIA CELLS OF RATS: ALTERATIONS INDUCED FOLLOWING METASTASIS TO THE LIVER

Potential role of activated macrophages in acetaminophen hepatotoxicity: I. Isolation and characterization of activated macrophages from rat liver

FDA comments on phase I clinical trials without vector biodistribution data

TNF-alpha is a principal cytokine involved in the recruitment of NK cells to liver parenchyma

Potential role of activated macrophages in acetaminophen hepatotoxicity: II. Mechanism of macrophage accumulation and activation

Potential role of activated macrophages in acetaminophen hepatotoxicity

Potential role of activated macrophages in acetaminophen hepatotoxicity

c-Ets-1 protein is hyperphosphorylated during mitosis

Purification and cloning of a novel serine protease, RNK-Tryp-2, from the granules of a rat NK cell leukemia

Quantitative analysis of rod-cored vesicles and dense granules of large granular lymphocytes in the liver, spleen, and peripheral blood of rats

Substrate-specific proteases (BLT-esterase) are localized predominantly in the natural killer cells of unprimed mice

An improved in vitro assay to quantitate chemotaxis of rat peripheral blood large granular lymphocytes (LGL)

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