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The selective GSK3 inhibitor, SAR502250, displays neuroprotective activity and attenuates behavioral impairments in models of neuropsychiatric symptoms of Alzheimer's disease in rodents

Scientific reports, 2019-12, Vol.9 (1), p.18045-15, Article 18045

2019

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The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

Scientific reports, 2018-02, Vol.8 (1), p.2416-25, Article 2416

2018

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Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat

Psychopharmacology, 2009-01, Vol.202 (1-3), p.385-396

2009

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Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet

Frontiers in endocrinology (Lausanne), 2014-01, Vol.5, p.49

2014

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Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3′S)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)phenyl] amide as histamine H3 receptor antagonist for the treatment of depression

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6269-6273

2013

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Stimulation of the β3-Adrenoceptor as a Novel Treatment Strategy for Anxiety and Depressive Disorders

Neuropsychopharmacology (New York, N.Y.), 2007-04, Vol.33 (3), p.574-587

2007

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SSR180711, a Novel Selective α7 Nicotinic Receptor Partial Agonist: (II) Efficacy in Experimental Models Predictive of Activity Against Cognitive Symptoms of Schizophrenia

Neuropsychopharmacology (New York, N.Y.), 2007-01, Vol.32 (1), p.17-34

2007

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The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia

Scientific reports, 2016-10, Vol.6 (1), p.35320-35320, Article 35320

2016

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Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia

Pharmacology, biochemistry and behavior, 2008-11, Vol.91 (1), p.47-58

2008

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Synthesis and biological evaluation of analogues of M6G

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.4035-4041

2011

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AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents

Psychopharmacologia, 2011-05, Vol.215 (1), p.149-163

2011

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SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

Pharmacology, biochemistry and behavior, 2012-08, Vol.102 (2), p.203-214

2012

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Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3a2S)-2-methyl-[1,3a2]bipyrrolidinyl-1a2-yl)phe nyl] amide as histamine H3 receptor antagonist for the treatment of depression

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6269-6273

2013

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Discovery of a potent, selective, and orally bioavailable histamine H3 receptor antagonist SAR110068 for the treatment of sleepawake disorders

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (22), p.6141-6145

2013

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Discovery of a potent, selective, and orally bioavailable histamine H3 receptor antagonist SAR110068 for the treatment of sleep–wake disorders

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (22), p.6141-6145

2013

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The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition

Pharmacology, biochemistry and behavior, 2011-05, Vol.98 (3), p.405-411

2011

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Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia : latent inhibition studies in the rat: Special Issue on Cognitive Enhancers

Psychopharmacologia, 2009, Vol.202 (1-3), p.385-396

2009

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Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression

Bioorganic & medicinal chemistry letters, 2013-12, Vol.23 (23), p.6269-6273

2013

Volltextzugriff (PDF)

Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders

Neuropsychopharmacology (New York, N.Y.), 2008-02, Vol.33 (3), p.574

2008

Volltextzugriff (PDF)

Stimulation of the [beta]3-Adrenoceptor as a Novel Treatment Strategy for Anxiety and Depressive Disorders

Neuropsychopharmacology (New York, N.Y.), 2008-02, Vol.33 (3), p.574

2008

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SSRI80711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia

Neuropsychopharmacology (New York, N.Y.), 2007, Vol.32 (1), p.17-34

2007

Volltextzugriff (PDF)

SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia

Neuropsychopharmacology (New York, N.Y.), 2007-01, Vol.32 (1), p.17

2007

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SSR180711, a Novel Selective 7 Nicotinic Receptor Partial Agonist: (II) Efficacy in Experimental Models Predictive of Activity Against Cognitive Symptoms of Schizophrenia

Neuropsychopharmacology (New York, N.Y.), 2007-01, Vol.32 (1), p.17-34

2007

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Decreased GABA B receptors in helpless rats: reversal by tricyclic antidepressants

Neuropsychobiology, 1989-01, Vol.22 (4), p.220

1989

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The selective GSK3 inhibitor, SAR502250, displays neuroprotective activity and attenuates behavioral impairments in models of neuropsychiatric symptoms of Alzheimer's disease in rodents

The selective reversible FAAH inhibitor, SSR411298, restores the development of maladaptive behaviors to acute and chronic stress in rodents

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia: latent inhibition studies in the rat

Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet

Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3′S)-2-methyl-[1,3′]bipyrrolidinyl-1′-yl)phenyl] amide as histamine H3 receptor antagonist for the treatment of depression

Stimulation of the β3-Adrenoceptor as a Novel Treatment Strategy for Anxiety and Depressive Disorders

SSR180711, a Novel Selective α7 Nicotinic Receptor Partial Agonist: (II) Efficacy in Experimental Models Predictive of Activity Against Cognitive Symptoms of Schizophrenia

The mGluR2 positive allosteric modulator, SAR218645, improves memory and attention deficits in translational models of cognitive symptoms associated with schizophrenia

Characterization of SSR103800, a selective inhibitor of the glycine transporter-1 in models predictive of therapeutic activity in schizophrenia

Synthesis and biological evaluation of analogues of M6G

AVE1625, a cannabinoid CB1 receptor antagonist, as a co-treatment with antipsychotics for schizophrenia: improvement in cognitive function and reduction of antipsychotic-side effects in rodents

SAR110894, a potent histamine H3-receptor antagonist, displays procognitive effects in rodents

Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3a2S)-2-methyl-[1,3a2]bipyrrolidinyl-1a2-yl)phe nyl] amide as histamine H3 receptor antagonist for the treatment of depression

Discovery of a potent, selective, and orally bioavailable histamine H3 receptor antagonist SAR110068 for the treatment of sleepawake disorders

Discovery of a potent, selective, and orally bioavailable histamine H3 receptor antagonist SAR110068 for the treatment of sleep–wake disorders

The neurokinin NK2 antagonist, saredutant, ameliorates stress-induced conditions without impairing cognition

Procognitive and antipsychotic efficacy of glycine transport 1 inhibitors (GlyT1) in acute and neurodevelopmental models of schizophrenia : latent inhibition studies in the rat: Special Issue on Cognitive Enhancers

Identification and profiling of 3,5-dimethyl-isoxazole-4-carboxylic acid [2-methyl-4-((2S,3'S)-2-methyl-[1,3']bipyrrolidinyl-1'-yl)phenyl] amide as histamine H(3) receptor antagonist for the treatment of depression

Stimulation of the beta3-Adrenoceptor as a novel treatment strategy for anxiety and depressive disorders

Stimulation of the [beta]3-Adrenoceptor as a Novel Treatment Strategy for Anxiety and Depressive Disorders

SSRI80711, a novel selective α7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia

SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (II) efficacy in experimental models predictive of activity against cognitive symptoms of schizophrenia

SSR180711, a Novel Selective 7 Nicotinic Receptor Partial Agonist: (II) Efficacy in Experimental Models Predictive of Activity Against Cognitive Symptoms of Schizophrenia

Decreased GABA B receptors in helpless rats: reversal by tricyclic antidepressants

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