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The role of mitochondria in insulin resistance and type 2 diabetes mellitus

Nature reviews. Endocrinology, 2012-02, Vol.8 (2), p.92

2012

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Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes

Nutrition & diabetes, 2022-08, Vol.12 (1), p.35-35, Article 35

2022

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Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Nature communications, 2020-04, Vol.11 (1), p.1891-1891, Article 1891

2020

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Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (26), p.9597-9602

2014

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Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (30), p.7789-7794

2018

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Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

The American journal of clinical nutrition, 2020-08, Vol.112 (2), p.413-426

2020

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The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact

Trends in pharmacological sciences (Regular ed.), 2011-10, Vol.32 (10), p.607-616

2011

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Metabolic responses to mild cold acclimation in type 2 diabetes patients

Nature communications, 2021-03, Vol.12 (1), p.1516-1516, Article 1516

2021

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Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

Diabetes (New York, N.Y.), 2010-03, Vol.59 (3), p.572-579

2010

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A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Nature communications, 2022-06, Vol.13 (1), p.3508-3508, Article 3508

2022

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Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Diabetes (New York, N.Y.), 2008-11, Vol.57 (11), p.2943-2949

2008

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Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

Diabetes (New York, N.Y.), 2015-04, Vol.64 (4), p.1193-1201

2015

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The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity

International Journal of Obesity, 2021-07, Vol.45 (7), p.1510-1520

2021

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Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women

Diabetologia, 2021-12, Vol.64 (12), p.2817-2828

2021

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Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial

EBioMedicine, 2019-11, Vol.49, p.318-330

2019

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Relationships between mitochondrial function and metabolic flexibility in type 2 diabetes mellitus

PloS one, 2013-02, Vol.8 (2), p.e51648-e51648

2013

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PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Journal of lipid research, 2013-02, Vol.54 (2), p.522-534

2013

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Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

The Journal of clinical investigation, 2014-11, Vol.124 (11), p.4915-4925

2014

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L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility

PloS one, 2020-09, Vol.15 (9), p.e0239506-e0239506

2020

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Verbetering van het glucosemetabolisme als gevolg van hogere aminozuurverbranding: Een placebo-gerandomiseerde klinische studie met als doel het vertakte-ketenaminozuurkatabolisme farmacologisch te verhogen in mensen met type 2-diabetes

Nederlands Tijdschrift voor Diabetolog, 2023-06, Vol.21 (2), p.12-15

Phielix, Esther

2023

Volltextzugriff (PDF)

Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism

Molecular metabolism (Germany), 2022-12, Vol.66, p.101620-101620, Article 101620

2022

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Verbetering van het glucosemetabolisme als gevolg van hogere aminozuurverbranding

Nederlands Tijdschrift voor Diabetolog, 2023-01, Vol.21 (2), p.12-15

Phielix Esther

2023

Volltextzugriff (PDF)

Evaluation of Muscle microRNA Expression in Relation to Human Peripheral Insulin Sensitivity: A Cross-Sectional Study in Metabolically Distinct Subject Groups

Frontiers in physiology, 2017-09, Vol.8, p.711-711

2017

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Supramolecular structure of dietary fat in early life modulates expression of markers for mitochondrial content and capacity in adipose tissue of adult mice

Nutrition & metabolism, 2017-06, Vol.14 (1), p.37-37, Article 37

2017

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The role of mitochondria in insulin resistance and type 2 diabetes mellitus

Role of branched-chain amino acid metabolism in the pathogenesis of obesity and type 2 diabetes-related metabolic disturbances BCAA metabolism in type 2 diabetes

Hepatic saturated fatty acid fraction is associated with de novo lipogenesis and hepatic insulin resistance

Role of diacylglycerol activation of PKCθ in lipid-induced muscle insulin resistance in humans

Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

Nicotinamide riboside supplementation alters body composition and skeletal muscle acetylcarnitine concentrations in healthy obese humans

The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact

Metabolic responses to mild cold acclimation in type 2 diabetes patients

Restoration of Muscle Mitochondrial Function and Metabolic Flexibility in Type 2 Diabetes by Exercise Training Is Paralleled by Increased Myocellular Fat Storage and Improved Insulin Sensitivity

A randomized placebo-controlled clinical trial for pharmacological activation of BCAA catabolism in patients with type 2 diabetes

Lower Intrinsic ADP-Stimulated Mitochondrial Respiration Underlies In Vivo Mitochondrial Dysfunction in Muscle of Male Type 2 Diabetic Patients

Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans

One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension

The effect of physical activity level and exercise training on the association between plasma branched-chain amino acids and intrahepatic lipid content in participants with obesity

Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women

Carnitine supplementation improves metabolic flexibility and skeletal muscle acetylcarnitine formation in volunteers with impaired glucose tolerance: A randomised controlled trial

Relationships between mitochondrial function and metabolic flexibility in type 2 diabetes mellitus

PPARγ coactivator-1α contributes to exercise-induced regulation of intramuscular lipid droplet programming in mice and humans

Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection

L-carnitine infusion does not alleviate lipid-induced insulin resistance and metabolic inflexibility

Verbetering van het glucosemetabolisme als gevolg van hogere aminozuurverbranding: Een placebo-gerandomiseerde klinische studie met als doel het vertakte-ketenaminozuurkatabolisme farmacologisch te verhogen in mensen met type 2-diabetes

Effects of SGLT2 inhibitor dapagliflozin in patients with type 2 diabetes on skeletal muscle cellular metabolism

Verbetering van het glucosemetabolisme als gevolg van hogere aminozuurverbranding

Evaluation of Muscle microRNA Expression in Relation to Human Peripheral Insulin Sensitivity: A Cross-Sectional Study in Metabolically Distinct Subject Groups

Supramolecular structure of dietary fat in early life modulates expression of markers for mitochondrial content and capacity in adipose tissue of adult mice

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