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Structure and Clinical Relevance of the Epidermal Growth Factor Receptor in Human Cancer

Journal of clinical oncology, 2008-04, Vol.26 (10), p.1742-1751

2008

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Synthesis of Camphor-Derived Bis(pyrazolylpyridine) Rhodium(III) Complexes: Structure–Reactivity Relationships and Biological Activity

Inorganic chemistry, 2019-01, Vol.58 (1), p.307-319

2019

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Domain Mapping of the Polycystin-2 C-terminal Tail Using de Novo Molecular Modeling and Biophysical Analysis

The Journal of biological chemistry, 2008-10, Vol.283 (42), p.28305-28312

2008

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Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca²⁺-dependent regulation of polycystin-2 channel activity

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (20), p.9176-9181

2010

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The Crystal Structure of Human Cyclin B

Cell cycle (Georgetown, Tex.), 2007-06, Vol.6 (11), p.1342-1349

2007

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Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2

American Journal of Physiology - Renal Physiology, 2009-11, Vol.297 (5), p.F1310-F1315

2009

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Characterization of NCS1–InsP3R1 interaction and its functional significance

The Journal of biological chemistry, 2019-12, Vol.294 (49), p.18923-18933

2019

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In silico ADMET analysis of the A-, B- and D-modified androstane derivatives with potential anticancer effects

Steroids, 2023-01, Vol.189, p.109147-109147, Article 109147

2023

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Development of new steroid-based hydrazide and (thio)semicarbazone compounds with anticancer properties

The Journal of steroid biochemistry and molecular biology, 2024-09, Vol.242, p.106545, Article 106545

2024

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Expression and purification of active human 17β-Hydroxysteroid dehydrogenase type 1 from Escherichia coli

Acta chimica Slovenica, 2024-04, Vol.71 (2), p.256

2024

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Identification of a metallothionein gene in honey bee Apis mellifera and its expression profile in response to Cd, Cu and Pb exposure

Molecular ecology, 2019-02, Vol.28 (4), p.731-745

2019

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Novel D-modified heterocyclic androstane derivatives as potential anticancer agents: Synthesis, characterization, in vitro and in silico studies

The Journal of steroid biochemistry and molecular biology, 2023-10, Vol.233, p.106362-106362, Article 106362

2023

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Synthesis, in vitro and in silico anticancer evaluation of novel pyridin-2-yl estra-1,3,5(10)-triene derivatives

Future medicinal chemistry, 2024-06, Vol.16 (11), p.1127-1145

2024

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Investigation of the Potential of Bile Acid Methyl Esters as Inhibitors of Aldo‐keto Reductase 1C2: Insight from Molecular Docking, Virtual Screening, Experimental Assays and Molecular Dynamics

Molecular informatics, 2022-10, Vol.41 (10), p.e2100256-n/a

2022

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Identification of d-seco modified steroid derivatives with affinity for estrogen receptor α and β isoforms using a non-transcriptional fluorescent cell assay in yeast

Steroids, 2018-02, Vol.130, p.22-30

2018

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Calcium-induced Conformational Changes in C-terminal Tail of Polycystin-2 Are Necessary for Channel Gating

The Journal of biological chemistry, 2012-05, Vol.287 (21), p.17232-17240

2012

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X-ray structure of human aldo-keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis

RSC medicinal chemistry, 2023-02, Vol.14 (2), p.341-355

2023

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The number and location of EF hand motifs dictates the calcium dependence of polycystin‐2 function

The FASEB journal, 2014-05, Vol.28 (5), p.2332-2346

2014

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The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded

FEBS letters, 2002-09, Vol.527 (1-3), p.303-308

2002

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Evaluation of A-ring fused pyridine d-modified androstane derivatives for antiproliferative and aldo-keto reductase 1C3 inhibitory activity

MedChemComm, 2018-06, Vol.9 (6), p.969-981

2018

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Microwave-assisted green synthesis of bile acid derivatives and evaluation of glucocorticoid receptor binding

RSC medicinal chemistry, 2021-03, Vol.12 (2), p.278-287

2021

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Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: Identification of a selective inhibitor of hormone-independent breast cancer cells

Bioorganic & medicinal chemistry, 2015-02, Vol.23 (4), p.703-711

2015

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17(E)-Picolinylidene androstane derivatives as potential inhibitors of prostate cancer cell growth: Antiproliferative activity and molecular docking studies

Bioorganic & medicinal chemistry, 2013-12, Vol.21 (23), p.7257-7266

2013

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Antihormonal potential of selected D-homo and D-seco estratriene derivatives

Steroids, 2015-05, Vol.97, p.45-53

2015

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In situ proteolysis of an N‐terminal His tag with thrombin improves the diffraction quality of human aldo‐keto reductase 1C3 crystals

Acta crystallographica. Section F, Structural biology communications, 2018-05, Vol.74 (5), p.300-306

2018

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Structure and Clinical Relevance of the Epidermal Growth Factor Receptor in Human Cancer

Synthesis of Camphor-Derived Bis(pyrazolylpyridine) Rhodium(III) Complexes: Structure–Reactivity Relationships and Biological Activity

Domain Mapping of the Polycystin-2 C-terminal Tail Using de Novo Molecular Modeling and Biophysical Analysis

Structure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca²⁺-dependent regulation of polycystin-2 channel activity

The Crystal Structure of Human Cyclin B

Analysis of the cytoplasmic interaction between polycystin-1 and polycystin-2

Characterization of NCS1–InsP3R1 interaction and its functional significance

In silico ADMET analysis of the A-, B- and D-modified androstane derivatives with potential anticancer effects

Development of new steroid-based hydrazide and (thio)semicarbazone compounds with anticancer properties

Expression and purification of active human 17β-Hydroxysteroid dehydrogenase type 1 from Escherichia coli

Identification of a metallothionein gene in honey bee Apis mellifera and its expression profile in response to Cd, Cu and Pb exposure

Novel D-modified heterocyclic androstane derivatives as potential anticancer agents: Synthesis, characterization, in vitro and in silico studies

Synthesis, in vitro and in silico anticancer evaluation of novel pyridin-2-yl estra-1,3,5(10)-triene derivatives

Investigation of the Potential of Bile Acid Methyl Esters as Inhibitors of Aldo‐keto Reductase 1C2: Insight from Molecular Docking, Virtual Screening, Experimental Assays and Molecular Dynamics

Identification of d-seco modified steroid derivatives with affinity for estrogen receptor α and β isoforms using a non-transcriptional fluorescent cell assay in yeast

Calcium-induced Conformational Changes in C-terminal Tail of Polycystin-2 Are Necessary for Channel Gating

X-ray structure of human aldo-keto reductase 1C3 in complex with a bile acid fused tetrazole inhibitor: experimental validation, molecular docking and structural analysis

The number and location of EF hand motifs dictates the calcium dependence of polycystin‐2 function

The regions of securin and cyclin B proteins recognized by the ubiquitination machinery are natively unfolded

Evaluation of A-ring fused pyridine d-modified androstane derivatives for antiproliferative and aldo-keto reductase 1C3 inhibitory activity

Microwave-assisted green synthesis of bile acid derivatives and evaluation of glucocorticoid receptor binding

Synthesis and anticancer cell potential of steroidal 16,17-seco-16,17a-dinitriles: Identification of a selective inhibitor of hormone-independent breast cancer cells

17(E)-Picolinylidene androstane derivatives as potential inhibitors of prostate cancer cell growth: Antiproliferative activity and molecular docking studies

Antihormonal potential of selected D-homo and D-seco estratriene derivatives

In situ proteolysis of an N‐terminal His tag with thrombin improves the diffraction quality of human aldo‐keto reductase 1C3 crystals

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