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The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

Nature (London), 2014-06, Vol.510 (7503), p.84-91

2014

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Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

Diabetes (New York, N.Y.), 2006-12, Vol.55 (Supplement 2), p.S9-S15

2006

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Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Cell, 2015-02, Vol.160 (4), p.745-758

2015

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Metabolic control analysis of hepatic glycogen synthesis in vivo

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (14), p.8166-8176

2020

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Lipid-induced insulin resistance: unravelling the mechanism

The Lancet (British edition), 2010-06, Vol.375 (9733), p.2267-2277

2010

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Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

PLoS medicine, 2005-09, Vol.2 (9), p.e233-e233

2005

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Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications: Potential Role of Alterations in Mitochondrial Function in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

Endocrinology (Philadelphia), 2020-04, Vol.161 (4), p.1

2020

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Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Diabetes (New York, N.Y.), 2012-11, Vol.61 (11), p.2711-2717

2012

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Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

Nature medicine, 2018-09, Vol.24 (9), p.1384-1394

2018

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Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans

Cell reports (Cambridge), 2017-06, Vol.19 (10), p.1997-2004

2017

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Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Endocrinology (Philadelphia), 2013-03, Vol.154 (3), p.1021-1028

2013

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Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

Diabetes (New York, N.Y.), 2007-05, Vol.56 (5), p.1376-1381

2007

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Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

Cell metabolism, 2010-12, Vol.12 (6), p.668-674

2010

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Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy

Journal of cerebral blood flow and metabolism, 2010-01, Vol.30 (1), p.211-221

2010

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Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

Proceedings of the National Academy of Sciences - PNAS, 2008-12, Vol.105 (50), p.19926-19931

2008

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Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7347-7354

2020

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Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance

Physiological reviews, 2007-04, Vol.87 (2), p.507-520

2007

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Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

Cell, 2018-01, Vol.172 (1-2), p.234-248.e17

2018

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Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (8), p.2212-2217

2016

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Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

The Journal of clinical investigation, 2002-05, Vol.109 (10), p.1321-1326

2002

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Role of patatin‐like phospholipase domain‐containing 3 on lipid‐induced hepatic steatosis and insulin resistance in rats

Hepatology (Baltimore, Md.), 2013-05, Vol.57 (5), p.1763-1772

2013

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Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus

The American journal of cardiology, 2002-09, Vol.90 (5), p.11-18

2002

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Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice

Diabetologia, 2023-03, Vol.66 (3), p.567-578

2023

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Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

The journal of clinical endocrinology and metabolism, 2011-12, Vol.96 (12), p.3873-3880

2011

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The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes

Diabetes (New York, N.Y.), 2002-03, Vol.51 (3), p.797-802

2002

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The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes

Molecular Mechanisms of Insulin Resistance in Humans and Their Potential Links With Mitochondrial Dysfunction

Hepatic Acetyl CoA Links Adipose Tissue Inflammation to Hepatic Insulin Resistance and Type 2 Diabetes

Metabolic control analysis of hepatic glycogen synthesis in vivo

Lipid-induced insulin resistance: unravelling the mechanism

Decreased insulin-stimulated ATP synthesis and phosphate transport in muscle of insulin-resistant offspring of type 2 diabetic parents

Mitochondrial Dysfunction, Insulin Resistance, and Potential Genetic Implications: Potential Role of Alterations in Mitochondrial Function in the Pathogenesis of Insulin Resistance and Type 2 Diabetes

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

Metformin inhibits gluconeogenesis via a redox-dependent mechanism in vivo

Hepatic Diacylglycerol-Associated Protein Kinase Cε Translocation Links Hepatic Steatosis to Hepatic Insulin Resistance in Humans

Cellular Mechanism by Which Estradiol Protects Female Ovariectomized Mice From High-Fat Diet-Induced Hepatic and Muscle Insulin Resistance

Impaired Mitochondrial Substrate Oxidation in Muscle of Insulin-Resistant Offspring of Type 2 Diabetic Patients

Targeted Expression of Catalase to Mitochondria Prevents Age-Associated Reductions in Mitochondrial Function and Insulin Resistance

Altered Brain Mitochondrial Metabolism in Healthy Aging as Assessed by in vivo Magnetic Resonance Spectroscopy

Paradoxical effects of increased expression of PGC-1α on muscle mitochondrial function and insulin-stimulated muscle glucose metabolism

Effect of a ketogenic diet on hepatic steatosis and hepatic mitochondrial metabolism in nonalcoholic fatty liver disease

Disordered Lipid Metabolism and the Pathogenesis of Insulin Resistance

Leptin Mediates a Glucose-Fatty Acid Cycle to Maintain Glucose Homeostasis in Starvation

Anti-myostatin antibody increases muscle mass and strength and improves insulin sensitivity in old mice

Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes

Role of patatin‐like phospholipase domain‐containing 3 on lipid‐induced hepatic steatosis and insulin resistance in rats

Pathogenesis of skeletal muscle insulin resistance in type 2 diabetes mellitus

Distinct subcellular localisation of intramyocellular lipids and reduced PKCε/PKCθ activity preserve muscle insulin sensitivity in exercise-trained mice

Disassociation of Liver and Muscle Insulin Resistance from Ectopic Lipid Accumulation in Low-Birth-Weight Individuals

The Effects of Rosiglitazone on Insulin Sensitivity, Lipolysis, and Hepatic and Skeletal Muscle Triglyceride Content in Patients With Type 2 Diabetes

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