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Cancer metabolism: a therapeutic perspective

Nature reviews. Clinical oncology, 2017-01, Vol.14 (1), p.11-31

2017

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CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

Cancer research (Chicago, Ill.), 2012-08, Vol.72 (15), p.3839-3850

2012

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CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis

Cell cycle (Georgetown, Tex.), 2012-10, Vol.11 (19), p.3599-3610

2012

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Recent advances of highly selective CDK4/6 inhibitors in breast cancer

Journal of hematology and oncology, 2017-04, Vol.10 (1), p.97-12, Article 97

2017

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Recent advances of bispecific antibodies in solid tumors

Journal of hematology and oncology, 2017-09, Vol.10 (1), p.155-155, Article 155

2017

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Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production

Cell cycle (Georgetown, Tex.), 2012-06, Vol.11 (12), p.2285-2302

2012

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Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production

Cell cycle (Georgetown, Tex.), 2012-08, Vol.11 (16), p.3019-3035

2012

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Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

Cell cycle (Georgetown, Tex.), 2010-09, Vol.9 (17), p.3506-3514

2010

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The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

Cell cycle (Georgetown, Tex.), 2009-12, Vol.8 (23), p.3984-4001

2009

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CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

Cell cycle (Georgetown, Tex.), 2012-06, Vol.11 (12), p.2272-2284

2012

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New Roles of Cyclin D1

The American journal of pathology, 2013-07, Vol.183 (1), p.3-9

Pestell, Richard G

2013

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DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis

Journal of hematology and oncology, 2018-04, Vol.11 (1), p.53-16, Article 53

2018

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CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion

Cancer research (Chicago, Ill.), 2018-04, Vol.78 (7), p.1657-1671

2018

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Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

Annual review of pathology, 2012-01, Vol.7 (1), p.423-467

2012

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Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: Implications for PET imaging of human tumors

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (15), p.2504-2520

2011

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Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

Breast cancer research : BCR, 2021-01, Vol.23 (1), p.11-11, Article 11

2021

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Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics

Cell cycle (Georgetown, Tex.), 2011-04, Vol.10 (8), p.1271-1286

2011

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An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

The American journal of pathology, 2009-06, Vol.174 (6), p.2023-2034

2009

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Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

Cell cycle (Georgetown, Tex.), 2011-06, Vol.10 (11), p.1772-1783

2011

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microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

Proceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (18), p.8231-8236

2010

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A Cyclin D1/microRNA 17/20 Regulatory Feedback Loop in Control of Breast Cancer Cell Proliferation

The Journal of cell biology, 2008-08, Vol.182 (3), p.509-517

2008

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Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: The seed and soil also needs "fertilizer"

Cell cycle (Georgetown, Tex.), 2011-08, Vol.10 (15), p.2440-2449

2011

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Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: Understanding the aging and cancer connection

Cell cycle (Georgetown, Tex.), 2011-12, Vol.10 (23), p.4065-4073

2011

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Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

Breast cancer research : BCR, 2011-07, Vol.13 (4), p.213-213, Article 213

2011

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CCR5-Mediated Signaling Is Involved in Invasion of Glioblastoma Cells in Its Microenvironment

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4199

2020

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Cancer metabolism: a therapeutic perspective

CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells

CDK inhibitors (p16/p19/p21) induce senescence and autophagy in cancer-associated fibroblasts, "fueling" tumor growth via paracrine interactions, without an increase in neo-angiogenesis

Recent advances of highly selective CDK4/6 inhibitors in breast cancer

Recent advances of bispecific antibodies in solid tumors

Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with "Warburg-like" cancer metabolism and L-lactate production

Ketones and lactate "fuel" tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism

The reverse Warburg effect: Aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

CTGF drives autophagy, glycolysis and senescence in cancer-associated fibroblasts via HIF1 activation, metabolically promoting tumor growth

New Roles of Cyclin D1

DACH1 antagonizes CXCL8 to repress tumorigenesis of lung adenocarcinoma and improve prognosis

CCR5 Governs DNA Damage Repair and Breast Cancer Stem Cell Expansion

Caveolin-1 and cancer metabolism in the tumor microenvironment: markers, models, and mechanisms

Cancer cells metabolically "fertilize" the tumor microenvironment with hydrogen peroxide, driving the Warburg effect: Implications for PET imaging of human tumors

Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

Ketones and lactate increase cancer cell "stemness," driving recurrence, metastasis and poor clinical outcome in breast cancer: Achieving personalized medicine via Metabolo-Genomics

An Absence of Stromal Caveolin-1 Expression Predicts Early Tumor Recurrence and Poor Clinical Outcome in Human Breast Cancers

Evidence for a stromal-epithelial "lactate shuttle" in human tumors: MCT4 is a marker of oxidative stress in cancer-associated fibroblasts

microRNA 17/20 inhibits cellular invasion and tumor metastasis in breast cancer by heterotypic signaling

A Cyclin D1/microRNA 17/20 Regulatory Feedback Loop in Control of Breast Cancer Cell Proliferation

Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: The seed and soil also needs "fertilizer"

Mitochondrial oxidative stress in cancer-associated fibroblasts drives lactate production, promoting breast cancer tumor growth: Understanding the aging and cancer connection

Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment

CCR5-Mediated Signaling Is Involved in Invasion of Glioblastoma Cells in Its Microenvironment

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