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Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

Diabetologia, 2005-11, Vol.48 (11), p.2313-2321

2005

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Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

Diabetologia, 2010-12, Vol.53 (12), p.2600-2610

2010

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Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

The Journal of clinical investigation, 2001-12, Vol.108 (11), p.1631-1638

2001

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AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1

Cell death and differentiation, 2010-05, Vol.17 (5), p.774-786

2010

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Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR) a A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

Diabetologia, 1998-12, Vol.41 (12), p.1511-1515

1998

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Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

Science (American Association for the Advancement of Science), 1996-06, Vol.272 (5269), p.1785-1787

1996

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A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Nature genetics, 1998-10, Vol.20 (2), p.143-148

1998

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Candidate gene studies reveal that the WFS1 gene joins the expanding list of novel type 2 diabetes genes

Diabetologia, 2008-03, Vol.51 (3), p.391-393

2008

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Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

The New England journal of medicine, 1998-01, Vol.338 (4), p.226-230

1998

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Dysregulation of Insulin Secretion in Children With Congenital Hyperinsulinism due to Sulfonylurea Receptor Mutations

Diabetes (New York, N.Y.), 2001-02, Vol.50 (2), p.322-328

2001

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Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

Diabetologia, 2008-09, Vol.51 (9), p.1646-1652

2008

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Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy

Diabetes (New York, N.Y.), 1998-07, Vol.47 (7), p.1145-1151

1998

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Genetic epidemiology of diabetes

The Journal of clinical investigation, 2005-06, Vol.115 (6), p.1431-1439

2005

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Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

Diabetologia, 2008-04, Vol.51 (4), p.623-631

2008

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An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene expression (SAGE)

Diabetologia, 2004-02, Vol.47 (2), p.284-299

2004

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Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

Nature (London), 1992-03, Vol.356 (6365), p.162-164

1992

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Genetic Heterogeneity in Familial Hyperinsulinism

Human molecular genetics, 1998-07, Vol.7 (7), p.1119-1128

1998

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Glucokinase as pancreatic β cell glucose sensor and diabetes gene

The Journal of clinical investigation, 1993-11, Vol.92 (5), p.2092-2098

1993

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Clinical Characteristics of Subjects with a Missense Mutation in Glucokinase

Diabetic medicine, 1995-03, Vol.12 (3), p.209-217

1995

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Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene

Diabetes (New York, N.Y.), 1998-04, Vol.47 (4), p.598-605

1998

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Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells

Diabetologia, 2001-04, Vol.44 (4), p.453-463

2001

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Linkage of type 2 diabetes to the glucokinase gene

The Lancet (British edition), 1992-05, Vol.339 (8805), p.1307-1310

1992

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Glucose transporter protein content and glucose transport capacity in rat skeletal muscles

American journal of physiology: endocrinology and metabolism, 1990-10, Vol.259 (4), p.E593-E598

1990

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A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.681-685

2001

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Pooling Analysis of Genetic Data: The Association of Leptin Receptor (LEPR) Polymorphisms With Variables Related to Human Adiposity

Genetics (Austin), 2001-11, Vol.159 (3), p.1163-1178

2001

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Mice conditionally lacking the Wolfram gene in pancreatic islet beta cells exhibit diabetes as a result of enhanced endoplasmic reticulum stress and apoptosis

Conditional ablation of Gsk-3β in islet beta cells results in expanded mass and resistance to fat feeding-induced diabetes in mice

Islet beta cell expression of constitutively active Akt1/PKB alpha induces striking hypertrophy, hyperplasia, and hyperinsulinemia

AATF mediates an antiapoptotic effect of the unfolded protein response through transcriptional regulation of AKT1

Missense mutations in the pancreatic islet beta cell inwardly rectifying K+ channel gene (KIR6.2/BIR) a A meta-analysis suggests a role in the polygenic basis of Type II diabetes mellitus in Caucasians

Adenosine Diphosphate as an Intracellular Regulator of Insulin Secretion

A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome)

Candidate gene studies reveal that the WFS1 gene joins the expanding list of novel type 2 diabetes genes

Familial Hyperinsulinism Caused by an Activating Glucokinase Mutation

Dysregulation of Insulin Secretion in Children With Congenital Hyperinsulinism due to Sulfonylurea Receptor Mutations

Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation

Functional analyses of novel mutations in the sulfonylurea receptor 1 associated with persistent hyperinsulinemic hypoglycemia of infancy

Genetic epidemiology of diabetes

Mice with beta cell overexpression of glycogen synthase kinase-3β have reduced beta cell mass and proliferation

An expression profile of human pancreatic islet mRNAs by Serial Analysis of Gene expression (SAGE)

Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus

Genetic Heterogeneity in Familial Hyperinsulinism

Glucokinase as pancreatic β cell glucose sensor and diabetes gene

Clinical Characteristics of Subjects with a Missense Mutation in Glucokinase

Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene

Glucose and other insulin secretagogues induce, rather than inhibit, expression of Id-1 and Id-3 in pancreatic islet beta cells

Linkage of type 2 diabetes to the glucokinase gene

Glucose transporter protein content and glucose transport capacity in rat skeletal muscles

A Genome Scan for Type 2 Diabetes Susceptibility Loci in a Genetically Isolated Population

Pooling Analysis of Genetic Data: The Association of Leptin Receptor (LEPR) Polymorphisms With Variables Related to Human Adiposity

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