UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 156

Sortiert nach

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

Cancer research (Chicago, Ill.), 2010-02, Vol.70 (4), p.1544-1554

2010

Volltextzugriff (PDF)

Discovery and Development of Spleen Tyrosine Kinase (SYK) Inhibitors

Journal of medicinal chemistry, 2012-04, Vol.55 (8), p.3614-3643

2012

Volltextzugriff (PDF)

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

The Journal of pharmacology and experimental therapeutics, 2006-12, Vol.319 (3), p.998

2006

Volltextzugriff (PDF)

Developing structure–activity relationships from an HTS hit for inhibition of the Cks1–Skp2 protein–protein interaction

Bioorganic & medicinal chemistry letters, 2015-11, Vol.25 (22), p.5199-5202

2015

Volltextzugriff (PDF)

Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth

Molecular biology of the cell, 2005-12, Vol.16 (12), p.5621-5629

2005

Volltextzugriff (PDF)

JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice

The Journal of immunology (1950), 2009-08, Vol.183 (3), p.2183-2192

2009

Volltextzugriff (PDF)

Multiple roles for the receptor tyrosine kinase axl in tumor formation

Cancer research (Chicago, Ill.), 2005-10, Vol.65 (20), p.9294-9303

2005

Volltextzugriff (PDF)

The current status and the future of JAK2 inhibitors for the treatment of myeloproliferative diseases

International journal of hematology, 2010-03, Vol.91 (2), p.189-200

2010

Volltextzugriff (PDF)

Substrate Modification with Lysine 63-linked Ubiquitin Chains through the UBC13-UEV1A Ubiquitin-conjugating Enzyme

The Journal of biological chemistry, 2007-10, Vol.282 (41), p.29936-29945

2007

Volltextzugriff (PDF)

Noninvasive imaging of in vivo MuRF1 expression during muscle atrophy

PloS one, 2014-04, Vol.9 (4), p.e94032-e94032

2014

Volltextzugriff (PDF)

R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm

Blood, 2011-06, Vol.117 (25), p.6866-6875

2011

Volltextzugriff (PDF)

Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators

Journal of medicinal chemistry, 2023-12, Vol.66 (24), p.17086-17104

2023

Volltextzugriff (PDF)

Activation of the PKB/AKT Pathway by ICAM-2

Immunity (Cambridge, Mass.), 2002, Vol.16 (1), p.51-65

2002

Volltextzugriff (PDF)

Bicyclic pyrimidine compounds as potent IRAK4 inhibitors

Bioorganic & medicinal chemistry letters, 2022-10, Vol.73, p.128900-128900, Article 128900

2022

Volltextzugriff (PDF)

Discovery of 5‑Aryl-2,4-diaminopyrimidine Compounds as Potent and Selective IRAK4 Inhibitors

ACS medicinal chemistry letters, 2022-04, Vol.13 (4), p.714-719

2022

Volltextzugriff (PDF)

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419

Bioorganic & medicinal chemistry, 2022-10, Vol.71, p.116951-116951, Article 116951

2022

Volltextzugriff (PDF)

The Poxvirus p28 Virulence Factor Is an E3 Ubiquitin Ligase

The Journal of biological chemistry, 2004-12, Vol.279 (52), p.54110-54116

2004

Volltextzugriff (PDF)

Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate

ACS medicinal chemistry letters, 2022-11, Vol.13 (11), p.1805-1811

2022

Volltextzugriff (PDF)

Retrovirally Delivered Random Cyclic Peptide Libraries Yield Inhibitors of Interleukin-4 Signaling in Human B Cells

The Journal of biological chemistry, 2002-10, Vol.277 (40), p.37512-37518

2002

Volltextzugriff (PDF)

Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor

Clinical Immunology, 2007-09, Vol.124 (3), p.244-257

2007

Volltextzugriff (PDF)

Discovering patterns to extract protein–protein interactions from full texts

Bioinformatics, 2004-12, Vol.20 (18), p.3604-3612

2004

Volltextzugriff (PDF)

Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (11), p.2617-2621

2017

Volltextzugriff (PDF)

Janus kinase inhibition prevents cancer- and myocardial infarction-mediated diaphragm muscle weakness in mice

American journal of physiology. Regulatory, integrative and comparative physiology, 2016-04, Vol.310 (8), p.R707-R710

2016

Volltextzugriff (PDF)

The JAK-STAT pathway is critical in ventilator-induced diaphragm dysfunction

Molecular medicine (Cambridge, Mass.), 2015-02, Vol.20 (1), p.579-589

2015

Volltextzugriff (PDF)

1 – 25 von 156

Suche als RSS-Feed

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Geprüft (Peer-Review)
(143)
Mit Volltextzugriff
(143)

Publikationsform

Sprache

Englisch
(156)
Japanisch
(27)

Erscheinungsjahr

n.n

Thema

Science & Technology
(102)
Life Sciences & Biomedicine
(94)
Humans
(72)
Animals
(64)
Biochemistry & Molecular Biology
(39)
Biological And Medical Sciences
(38)
Mice
(29)
Molecular Sequence Data
(26)
Amino Acid Sequence
(25)
Medical Sciences
(22)
Fundamental And Applied Biological Sciences. Psychology
(19)
Rats
(19)
Pharmacology & Pharmacy
(18)
Cell Line
(16)
Immunology
(15)
Cell Biology
(13)
Cells, Cultured
(13)
Female
(13)
Base Sequence
(12)
Gene Expression
(12)

15 weitere anzeigen...

Weniger anzeigen...

Menü

Weitere Dienste

Einstellungen

R428, a Selective Small Molecule Inhibitor of Axl Kinase, Blocks Tumor Spread and Prolongs Survival in Models of Metastatic Breast Cancer

Discovery and Development of Spleen Tyrosine Kinase (SYK) Inhibitors

R406, an orally available spleen tyrosine kinase inhibitor blocks fc receptor signaling and reduces immune complex-mediated inflammation

Developing structure–activity relationships from an HTS hit for inhibition of the Cks1–Skp2 protein–protein interaction

AMPK activation through mitochondrial regulation results in increased substrate oxidation and improved metabolic parameters in models of diabetes

Critical role of the ubiquitin ligase activity of UHRF1, a nuclear RING finger protein, in tumor cell growth

JAK3 Inhibition Significantly Attenuates Psoriasiform Skin Inflammation in CD18 Mutant PL/J Mice

Multiple roles for the receptor tyrosine kinase axl in tumor formation

The current status and the future of JAK2 inhibitors for the treatment of myeloproliferative diseases

Substrate Modification with Lysine 63-linked Ubiquitin Chains through the UBC13-UEV1A Ubiquitin-conjugating Enzyme

Noninvasive imaging of in vivo MuRF1 expression during muscle atrophy

R723, a selective JAK2 inhibitor, effectively treats JAK2V617F-induced murine myeloproliferative neoplasm

Optimization of Pharmacokinetic and In Vitro Safety Profile of a Series of Pyridine Diamide Indirect AMPK Activators

Activation of the PKB/AKT Pathway by ICAM-2

Bicyclic pyrimidine compounds as potent IRAK4 inhibitors

Discovery of 5‑Aryl-2,4-diaminopyrimidine Compounds as Potent and Selective IRAK4 Inhibitors

Structure activity relationships leading to the identification of the indirect activator of AMPK, R419

The Poxvirus p28 Virulence Factor Is an E3 Ubiquitin Ligase

Optimization of Pyrimidine Compounds as Potent JAK1 Inhibitors and the Discovery of R507 as a Clinical Candidate

Retrovirally Delivered Random Cyclic Peptide Libraries Yield Inhibitors of Interleukin-4 Signaling in Human B Cells

Inflammation and bone erosion are suppressed in models of rheumatoid arthritis following treatment with a novel Syk inhibitor

Discovering patterns to extract protein–protein interactions from full texts

Developing DYRK inhibitors derived from the meridianins as a means of increasing levels of NFAT in the nucleus

Janus kinase inhibition prevents cancer- and myocardial infarction-mediated diaphragm muscle weakness in mice

The JAK-STAT pathway is critical in ventilator-induced diaphragm dysfunction

Suchergebnisse filtern