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Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function

Science (American Association for the Advancement of Science), 1999-04, Vol.284 (5413), p.455-461

1999

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Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5289), p.948-953

1996

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Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

Science (American Association for the Advancement of Science), 1996-11, Vol.274 (5289), p.1001-1005

1996

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Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade

Science (American Association for the Advancement of Science), 1999-11, Vol.286 (5443), p.1321-1326

1999

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Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

Genes & development, 1999-03, Vol.13 (6), p.666-674

1999

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Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

Nature (London), 1995-07, Vol.376 (6538), p.313-320

1995

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The Cell Cycle and Cancer

Proceedings of the National Academy of Sciences - PNAS, 1997-04, Vol.94 (7), p.2776-2778

1997

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Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

Nature (London), 1998-02, Vol.391 (6670), p.859-865

1998

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A structural basis for mutational inactivation of the tumour suppressor Smad4

Nature (London), 1997-07, Vol.388 (6637), p.87-93

1997

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Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

Science (American Association for the Advancement of Science), 1993-09, Vol.261 (5129), p.1701-1707

1993

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Zinc finger-DNA recognition : crystal structure of a Zif268-DNA complex at 2.1 Å

Science (American Association for the Advancement of Science), 1991-05, Vol.252 (5007), p.809-817

1991

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Crystal Structure of the Tetramerization Domain of the p53 Tumor Suppressor at 1.7 Angstroms

Science (American Association for the Advancement of Science), 1995-03, Vol.267 (5203), p.1498-1502

1995

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Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

Journal of molecular biology, 1999-04, Vol.287 (5), p.821-828

Pavletich, N P

1999

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Structure of a c-Cbl–UbcH7 Complex: RING Domain Function in Ubiquitin-Protein Ligases

Cell, 2000-08, Vol.102 (4), p.533-539

2000

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Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling

Science (American Association for the Advancement of Science), 2002-06, Vol.296 (5574), p.1886-1889

2002

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BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure

Science (American Association for the Advancement of Science), 2002-09, Vol.297 (5588), p.1837-1848

2002

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Nature (London), 1999-09, Vol.401 (6749), p.188-193

1999

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Structure of the histone deacetylase SIRT2

Nature structural & molecular biology, 2001-07, Vol.8 (7), p.621-625

2001

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Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association

Cell, 1999-10, Vol.99 (3), p.323-334

1999

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Role of the F-box Protein Skp2 in Lymphomagenesis

Proceedings of the National Academy of Sciences - PNAS, 2001-02, Vol.98 (5), p.2515-2520

2001

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Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

Cell, 1997-04, Vol.89 (2), p.239-250

1997

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In vivo Function of Hsp90 Is Dependent on ATP Binding and ATP Hydrolysis

The Journal of cell biology, 1998-11, Vol.143 (4), p.901-910

1998

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Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors

Genes & development, 2000-12, Vol.14 (24), p.3115-3125

2000

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Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Science (American Association for the Advancement of Science), 1994-07, Vol.265 (5170), p.346-355

1994

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Crystal Structure of a Smad MH1 Domain Bound to DNA: Insights on DNA Binding in TGF-β Signaling

Cell, 1998-09, Vol.94 (5), p.585-594

1998

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Structure of the VHL-ElonginC-ElonginB Complex: Implications for VHL Tumor Suppressor Function

Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain

Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

Structure of an E6AP-UbcH7 Complex: Insights into Ubiquitination by the E2- E3 Enzyme Cascade

Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

Mechanism of CDK activation revealed by the structure of a cyclinA-CDK2 complex

The Cell Cycle and Cancer

Structure of the retinoblastoma tumour-suppressor pocket domain bound to a peptide from HPV E7

A structural basis for mutational inactivation of the tumour suppressor Smad4

Crystal Structure of a Five-Finger GLI-DNA Complex: New Perspectives on Zinc Fingers

Zinc finger-DNA recognition : crystal structure of a Zif268-DNA complex at 2.1 Å

Crystal Structure of the Tetramerization Domain of the p53 Tumor Suppressor at 1.7 Angstroms

Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors

Structure of a c-Cbl–UbcH7 Complex: RING Domain Function in Ubiquitin-Protein Ligases

Structure of an HIF-1α-pVHL Complex: Hydroxyproline Recognition in Signaling

BRCA2 Function in DNA Binding and Recombination from a BRCA2-DSS1-ssDNA Structure

Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Structure of the histone deacetylase SIRT2

Crystal Structure of the PTEN Tumor Suppressor: Implications for Its Phosphoinositide Phosphatase Activity and Membrane Association

Role of the F-box Protein Skp2 in Lymphomagenesis

Crystal Structure of an Hsp90–Geldanamycin Complex: Targeting of a Protein Chaperone by an Antitumor Agent

In vivo Function of Hsp90 Is Dependent on ATP Binding and ATP Hydrolysis

Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors

Crystal Structure of a p53 Tumor Suppressor-DNA Complex: Understanding Tumorigenic Mutations

Crystal Structure of a Smad MH1 Domain Bound to DNA: Insights on DNA Binding in TGF-β Signaling

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