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Small and large animal models in cardiac contraction research: Advantages and disadvantages

Pharmacology & therapeutics (Oxford), 2014-03, Vol.141 (3), p.235-249

2014

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In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice

Circulation research, 2017-09, Vol.121 (8), p.923-929

2017

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Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts

European heart journal, 2015-09, Vol.36 (35), p.2390-2401

2015

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Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1

The Journal of clinical investigation, 2021-02, Vol.131 (4), p.1-16

2021

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Memantine, an NMDA receptor antagonist, attenuates cardiac remodeling, lipid peroxidation and neutrophil recruitment in heart failure: A cardioprotective agent?

Biomedicine & pharmacotherapy, 2018-12, Vol.108, p.1237-1243

2018

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Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy

The Journal of clinical investigation, 2007-04, Vol.117 (4), p.889-901

2007

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Determinants of frequency-dependent contraction and relaxation of mammalian myocardium

Journal of molecular and cellular cardiology, 2007-11, Vol.43 (5), p.523-531

2007

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Optical Mapping-Validated Machine Learning Improves Atrial Fibrillation Driver Detection by Multi-Electrode Mapping

Circulation. Arrhythmia and electrophysiology, 2020-10, Vol.13 (10), p.e008249-e008249

2020

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Increased phosphorylation of tropomyosin, troponin I, and myosin light chain-2 after stretch in rabbit ventricular myocardium under physiological conditions

Journal of molecular and cellular cardiology, 2010-05, Vol.48 (5), p.1023-1028

2010

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Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart

Circulation. Arrhythmia and electrophysiology, 2015-10, Vol.8 (5), p.1219-1227

2015

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Atrial Glutathione Content, Calcium Current, and Contractility

The Journal of biological chemistry, 2007-09, Vol.282 (38), p.28063-28073

2007

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Integration of High-Resolution Optical Mapping and 3-Dimensional Micro-Computed Tomographic Imaging to Resolve the Structural Basis of Atrial Conduction in the Human Heart

Circulation. Arrhythmia and electrophysiology, 2015-12, Vol.8 (6), p.1514-1517

2015

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Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium

Journal of molecular and cellular cardiology, 2021-07, Vol.156, p.7-19

2021

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Influence of metabolic dysfunction on cardiac mechanics in decompensated hypertrophy and heart failure

Journal of molecular and cellular cardiology, 2016-05, Vol.94, p.162-175

2016

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POS-432 DELETION OF THE POLYCYSTIN-1 COILED-COIL MOTIF LEADS TO A SEVERE FUNCTIONAL HYPOMORPHIC ADPKD ALLELE IN MICE: INSIGHTS INTO INTRACELLULAR MECHANISMS

Kidney international reports, 2021-04, Vol.6 (4), p.S187-S188

2021

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Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation

Archives of biochemistry and biophysics, 2013-07, Vol.535 (1), p.30-38

2013

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Differential involvement of various sources of reactive oxygen species in thyroxin-induced hemodynamic changes and contractile dysfunction of the heart and diaphragm muscles

Free radical biology & medicine, 2015-06, Vol.83, p.252-261

2015

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Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature

The Journal of general physiology, 2013-01, Vol.141 (1), p.133-139

2013

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The Rates of Ca2+ Dissociation and Cross-bridge Detachment from Ventricular Myofibrils as Reported by a Fluorescent Cardiac Troponin C

The Journal of biological chemistry, 2012-08, Vol.287 (33), p.27930-27940

2012

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Notch1 haploinsufficiency causes ascending aortic aneurysms in mice

JCI insight, 2017-11, Vol.2 (21)

2017

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Cardiomyopathy in the dystrophin/utrophin-deficient mouse model of severe muscular dystrophy is characterized by dysregulation of matrix metalloproteinases

Neuromuscular disorders : NMD, 2012-11, Vol.22 (11), p.1006-1014

2012

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Altered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy

Cardiovascular pathology, 2017-01, Vol.26, p.12-20

2017

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Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium

Archives of biochemistry and biophysics, 2013-07, Vol.535 (1), p.22-29

2013

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Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy

ESC Heart Failure, 2020-12, Vol.7 (6), p.3983-3995

2020

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Myocardial relaxation in human heart failure: Why sarcomere kinetics should be centerstage

Archives of biochemistry and biophysics, 2018-11, Vol.661, p.145-148

Janssen, Paul M.L.

2018

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Small and large animal models in cardiac contraction research: Advantages and disadvantages

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice

Atrial fibrillation driven by micro-anatomic intramural re-entry revealed by simultaneous sub-epicardial and sub-endocardial optical mapping in explanted human hearts

Paracardial fat remodeling affects systemic metabolism through alcohol dehydrogenase 1

Memantine, an NMDA receptor antagonist, attenuates cardiac remodeling, lipid peroxidation and neutrophil recruitment in heart failure: A cardioprotective agent?

Interplay of IKK/NF-κB signaling in macrophages and myofibers promotes muscle degeneration in Duchenne muscular dystrophy

Determinants of frequency-dependent contraction and relaxation of mammalian myocardium

Optical Mapping-Validated Machine Learning Improves Atrial Fibrillation Driver Detection by Multi-Electrode Mapping

Increased phosphorylation of tropomyosin, troponin I, and myosin light chain-2 after stretch in rabbit ventricular myocardium under physiological conditions

Molecular Mapping of Sinoatrial Node HCN Channel Expression in the Human Heart

Atrial Glutathione Content, Calcium Current, and Contractility

Integration of High-Resolution Optical Mapping and 3-Dimensional Micro-Computed Tomographic Imaging to Resolve the Structural Basis of Atrial Conduction in the Human Heart

Impact of etiology on force and kinetics of left ventricular end-stage failing human myocardium

Influence of metabolic dysfunction on cardiac mechanics in decompensated hypertrophy and heart failure

POS-432 DELETION OF THE POLYCYSTIN-1 COILED-COIL MOTIF LEADS TO A SEVERE FUNCTIONAL HYPOMORPHIC ADPKD ALLELE IN MICE: INSIGHTS INTO INTRACELLULAR MECHANISMS

Tropomyosin Ser-283 pseudo-phosphorylation slows myofibril relaxation

Differential involvement of various sources of reactive oxygen species in thyroxin-induced hemodynamic changes and contractile dysfunction of the heart and diaphragm muscles

Effect of muscle length on cross-bridge kinetics in intact cardiac trabeculae at body temperature

The Rates of Ca2+ Dissociation and Cross-bridge Detachment from Ventricular Myofibrils as Reported by a Fluorescent Cardiac Troponin C

Notch1 haploinsufficiency causes ascending aortic aneurysms in mice

Cardiomyopathy in the dystrophin/utrophin-deficient mouse model of severe muscular dystrophy is characterized by dysregulation of matrix metalloproteinases

Altered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy

Post-translational modifications of myofilament proteins involved in length-dependent prolongation of relaxation in rabbit right ventricular myocardium

Mineralocorticoid receptor antagonism by finerenone is sufficient to improve function in preclinical muscular dystrophy

Myocardial relaxation in human heart failure: Why sarcomere kinetics should be centerstage

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