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Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

Molecular cell, 2015-10, Vol.60 (1), p.177-188

2015

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FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Nature structural & molecular biology, 2020-03, Vol.27 (3), p.240

2020

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Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Nature (London), 2012-08, Vol.489 (7417), p.571-575

2012

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

Nature (London), 2011-07, Vol.475 (7354), p.53-58

2011

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The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

Molecular cell, 2014-06, Vol.54 (5), p.858-869

2014

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TRAIP is a master regulator of DNA interstrand crosslink repair

Nature (London), 2019-03, Vol.567 (7747), p.267-272

2019

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Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

Molecular cell, 2015-01, Vol.57 (1), p.150-164

2015

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Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

Nature (London), 2020-03, Vol.579 (7800), p.603-608

2020

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Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

Science (American Association for the Advancement of Science), 2010-07, Vol.329 (5988), p.219-223

2010

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Increased formate overflow is a hallmark of oxidative cancer

Nature communications, 2018-04, Vol.9 (1), p.1368-12, Article 1368

2018

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Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

Molecular cell, 2014-05, Vol.54 (3), p.472-484

2014

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Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome

Molecular cell, 2014-09, Vol.55 (6), p.807-817

2014

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Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

Nature genetics, 2011-02, Vol.43 (2), p.147-152

2011

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Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair

Molecular cell, 2007-12, Vol.28 (5), p.798-809

2007

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The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair

PloS one, 2012-05, Vol.7 (5), p.e36970-e36970

2012

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The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair

Nucleic acids research, 2009-07, Vol.37 (13), p.4360

2009

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Do Mutational Dynamics in Stem Cells Explain the Origin of Common Cancers?

Cell stem cell, 2015-02, Vol.16 (2), p.111-112

2015

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UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination

Molecular and Cellular Biology, 2007-12, Vol.27 (24), p.8421-8430

2007

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Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Nature (London), 2012-09, Vol.489 (7417), p.571

2012

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Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

Nature (London), 2018-01, Vol.553 (7687), p.171-177

2018

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The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

Nature structural & molecular biology, 2005-09, Vol.12 (9), p.763-771

2005

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Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Nature (London), 2017-08, Vol.548 (7669), p.549-554

2017

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Aldehydes and Fanconi anaemia: the enemy within

M.S. Médecine sciences, 2013-04, Vol.29 (4), p.361

2013

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A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells

Chemical science (Cambridge), 2017-05, Vol.8 (5), p.4073-4081

2017

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Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen

FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

The Genetic and Biochemical Basis of FANCD2 Monoubiquitination

TRAIP is a master regulator of DNA interstrand crosslink repair

Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

Alcohol-derived DNA crosslinks are repaired by two distinct mechanisms

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

Increased formate overflow is a hallmark of oxidative cancer

Mouse SLX4 Is a Tumor Suppressor that Stimulates the Activity of the Nuclease XPF-ERCC1 in DNA Crosslink Repair

Maternal Aldehyde Elimination during Pregnancy Preserves the Fetal Genome

Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia

Deubiquitination of FANCD2 Is Required for DNA Crosslink Repair

The Fanconi anaemia components UBE2T and FANCM are functionally linked to nucleotide excision repair

The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair

Do Mutational Dynamics in Stem Cells Explain the Origin of Common Cancers?

UBE2T, the Fanconi Anemia Core Complex, and FANCD2 Are Recruited Independently to Chromatin: a Basis for the Regulation of FANCD2 Monoubiquitination

Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function

Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells

The vertebrate Hef ortholog is a component of the Fanconi anemia tumor-suppressor pathway

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism

Aldehydes and Fanconi anaemia: the enemy within

A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells

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