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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

Immunity (Cambridge, Mass.), 2020-06, Vol.52 (6), p.978-993.e6

2020

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OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice

Nature communications, 2021-10, Vol.12 (1), p.5912-5912, Article 5912

2021

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RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

Nature (London), 2016-12, Vol.540 (7631), p.124-128

2016

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Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

Nature communications, 2020-04, Vol.11 (1), p.1747-1747, Article 1747

2020

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Connecting immune deficiency and inflammation

Science (American Association for the Advancement of Science), 2018-08, Vol.361 (6404), p.756-757

2018

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Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

Nature (London), 2019-11, Vol.575 (7784), p.683-687

2019

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The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts

Nature communications, 2018-02, Vol.9 (1), p.618-12, Article 618

2018

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RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

Nature (London), 2014-09, Vol.513 (7516), p.90-94

2014

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A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

Nature cell biology, 2019-06, Vol.21 (6), p.731-742

2019

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RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

Science (American Association for the Advancement of Science), 2016-08, Vol.353 (6299), p.603-608

2016

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MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

Molecular cell, 2017-06, Vol.66 (5), p.698-710.e5

2017

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ADAR1 averts fatal type I interferon induction by ZBP1

Nature (London), 2022-07, Vol.607 (7920), p.776-783

2022

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Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

eLife, 2014-12, Vol.3

2014

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Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

Immunity (Cambridge, Mass.), 2019-08, Vol.51 (2), p.367-380.e4

2019

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Synchronized renal tubular cell death involves ferroptosis

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16836-16841

2014

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Necroptosis and its role in inflammation

Nature (London), 2015-01, Vol.517 (7534), p.311-320

2015

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Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition

Nature communications, 2019-02, Vol.10 (1), p.688-688, Article 688

2019

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Regulation of tissue homeostasis by NF-[kappa]B signalling: implications for inflammatory diseases

Nature reviews. Immunology, 2009-11, Vol.9 (11), p.778

Pasparakis, Manolis

2009

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Epidermal p65/NF‐κB signalling is essential for skin carcinogenesis

EMBO molecular medicine, 2014-07, Vol.6 (7), p.970-983

2014

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CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice

Journal of cerebral blood flow and metabolism, 2020-12, Vol.40 (1_suppl), p.S98-S116

2020

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CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

Blood, 2012-07, Vol.120 (3), p.613-625

2012

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RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4

Immunity (Cambridge, Mass.), 2016-07, Vol.45 (1), p.46-59

2016

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IKKε and TBK1 prevent RIPK1 dependent and independent inflammation

Nature communications, 2024-01, Vol.15 (1), p.130-18, Article 130

2024

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Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

The Journal of immunology (1950), 2014-08, Vol.193 (4), p.1539-1543

2014

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Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes

PloS one, 2018-03, Vol.13 (3), p.e0194048-e0194048

2018

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FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells

OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice

RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation

Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation

Connecting immune deficiency and inflammation

Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts

RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis

A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain

RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS

MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death

ADAR1 averts fatal type I interferon induction by ZBP1

Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis

Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment

Synchronized renal tubular cell death involves ferroptosis

Necroptosis and its role in inflammation

Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition

Regulation of tissue homeostasis by NF-[kappa]B signalling: implications for inflammatory diseases

Epidermal p65/NF‐κB signalling is essential for skin carcinogenesis

CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice

CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4

IKKε and TBK1 prevent RIPK1 dependent and independent inflammation

Cutting edge: RIPK1 Kinase inactive mice are viable and protected from TNF-induced necroptosis in vivo

Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes

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