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Metabolism and antiviral activity of ribavirin

Virus research, 2005-02, Vol.107 (2), p.165-171

Parker, William B.

2005

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Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors

Annals of oncology, 2015-07, Vol.26 (7), p.1481-1487

2015

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Thiarabine, 1-(4-Thio-β-D-arabinofuranosyl)cytosine. A Deoxycytidine Analog With Excellent Anticancer Activity

Current medicinal chemistry, 2015-01, Vol.22 (34), p.3881-3896

2015

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In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells

Gene therapy, 2000-10, Vol.7 (20), p.1738-1743

2000

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Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells

Biochemical pharmacology, 1998-05, Vol.55 (10), p.1673-1681

1998

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Metabolism and mechanism of action of 5-fluorouracil

Pharmacology & therapeutics (Oxford), 1990, Vol.48 (3), p.381-395

1990

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Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase

Cancer gene therapy, 2011-06, Vol.18 (6), p.390-398

2011

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Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene

Cancer gene therapy, 2010-09, Vol.17 (9), p.614-623

2010

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Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene

Cancer research (Chicago, Ill.), 1995-08, Vol.55 (15), p.3339-3345

1995

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Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase

The Journal of biological chemistry, 2003-11, Vol.278 (47), p.47110-47118

2003

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Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol

Blood, 1998-01, Vol.91 (2), p.458-465

1998

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Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs

The Journal of biological chemistry, 1991-01, Vol.266 (3), p.1754-1762

1991

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Effects of 2-chloro-9-(3-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate

Cancer research (Chicago, Ill.), 1991-05, Vol.51 (9), p.2386-2394

1991

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Metabolism of carbovir, a potent inhibitor of human immunodeficiency virus type 1, and its effects on cellular metabolism

Antimicrobial Agents and Chemotherapy, 1993-05, Vol.37 (5), p.1004-1009

1993

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Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase

Molecular pharmacology, 1988-10, Vol.34 (4), p.485-491

1988

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CO2 Lasers and Temperature Changes of Titanium Implants

Journal of periodontology (1970), 1995-12, Vol.66 (12), p.1017-1024

1995

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SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-FLUORO ADENINE AND 6-METHYL PURINE NUCLEOSIDE ANALOGS AS PRODRUGS FOR SUICIDE GENE THERAPY OF CANCER

Nucleosides, nucleotides & nucleic acids, 2005-01, Vol.24 (5-7), p.881-885

2005

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Identification and Characterization of a Unique Adenosine Kinase from Mycobacterium tuberculosis

Journal of Bacteriology, 2003-11, Vol.185 (22), p.6548-6555

2003

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Dominant mutations causing alterations in acetyl-coenzyme A carboxylase confer tolerance to cyclohexanedione and aryloxyphenoxypropionate herbicides in maize

Proceedings of the National Academy of Sciences - PNAS, 1990-09, Vol.87 (18), p.7175-7179

1990

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Antimycobacterial activity of 2-methyl-adenosine

Journal of antimicrobial chemotherapy, 2003-11, Vol.52 (5), p.801-808

2003

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Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase

Cancer gene therapy, 2003-01, Vol.10 (1), p.23-29

2003

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Detectable Inhibition of Heparin-Binding Growth Factor Activity in Sera From Patients Treated With Pentosan Polysulfate

JNCI : Journal of the National Cancer Institute, 1993-07, Vol.85 (13), p.1068-1073

1993

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Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: Substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase

Antimicrobial agents and chemotherapy, 1998-05, Vol.42 (5), p.1045-1051

1998

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Placental transfer and fetal disposition of 2',3'-dideoxycytidine and 2',3'-dideoxyinosine in the rhesus monkey

Drug metabolism and disposition, 1995-08, Vol.23 (8), p.881

1995

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Interaction of Deoxyguanosine Nucleotide Analogs with Human Telomerase

Molecular pharmacology, 2000-04, Vol.57 (4), p.695-699

2000

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Metabolism and antiviral activity of ribavirin

Phase I dose-escalating trial of Escherichia coli purine nucleoside phosphorylase and fludarabine gene therapy for advanced solid tumors

Thiarabine, 1-(4-Thio-β-D-arabinofuranosyl)cytosine. A Deoxycytidine Analog With Excellent Anticancer Activity

In vivo sensitization of ovarian tumors to chemotherapy by expression of E. coli purine nucleoside phosphorylase in a small fraction of cells

Metabolism and Metabolic Actions of 6-Methylpurine and 2-Fluoroadenine in Human Cells

Metabolism and mechanism of action of 5-fluorouracil

Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase

Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene

Bystander killing of melanoma cells using the human tyrosinase promoter to express the Escherichia coli purine nucleoside phosphorylase gene

Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase

Early induction of apoptosis in hematopoietic cell lines after exposure to flavopiridol

Effects of 2-chloro-9-(3-deoxy-2-fluoro-β-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate

Metabolism of carbovir, a potent inhibitor of human immunodeficiency virus type 1, and its effects on cellular metabolism

Interaction of 2-halogenated dATP analogs (F, Cl, and Br) with human DNA polymerases, DNA primase, and ribonucleotide reductase

CO2 Lasers and Temperature Changes of Titanium Implants

SYNTHESIS AND BIOLOGICAL ACTIVITY OF 2-FLUORO ADENINE AND 6-METHYL PURINE NUCLEOSIDE ANALOGS AS PRODRUGS FOR SUICIDE GENE THERAPY OF CANCER

Identification and Characterization of a Unique Adenosine Kinase from Mycobacterium tuberculosis

Dominant mutations causing alterations in acetyl-coenzyme A carboxylase confer tolerance to cyclohexanedione and aryloxyphenoxypropionate herbicides in maize

Antimycobacterial activity of 2-methyl-adenosine

Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase

Detectable Inhibition of Heparin-Binding Growth Factor Activity in Sera From Patients Treated With Pentosan Polysulfate

Metabolism in human cells of the D and L enantiomers of the carbocyclic analog of 2'-deoxyguanosine: Substrate activity with deoxycytidine kinase, mitochondrial deoxyguanosine kinase, and 5'-nucleotidase

Placental transfer and fetal disposition of 2',3'-dideoxycytidine and 2',3'-dideoxyinosine in the rhesus monkey

Interaction of Deoxyguanosine Nucleotide Analogs with Human Telomerase

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