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Hypoxia-driven epigenetic regulation in cancer progression: A focus on histone methylation and its modifying enzymes

Cancer letters, 2020-10, Vol.489, p.41-49

2020

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Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer

Nature communications, 2020-10, Vol.11 (1), p.5436-5436, Article 5436

2020

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Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense

Oncogene, 2018-09, Vol.37 (38), p.5191-5204

2018

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Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells

Communications biology, 2020-10, Vol.3 (1), p.638-638, Article 638

2020

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Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway

Nature communications, 2018-10, Vol.9 (1), p.4113-14, Article 4113

2018

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Loss of EGR3 is an independent risk factor for metastatic progression in prostate cancer

Oncogene, 2020-09, Vol.39 (36), p.5839-5854

2020

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SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non―Small Cell Lung Cancers to Cisplatin and Doxorubicin

Cancer research (Chicago, Ill.), 2014, Vol.74 (1), p.298-308

2014

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The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src

Oncogene, 2018-10, Vol.37 (41), p.5552-5568

2018

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Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells

Oncogene, 2019-05, Vol.38 (19), p.3651-3666

2019

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Development of a rectally administrable Dnase1 to treat septic shock by targeting NETs

Life sciences (1973), 2024-04, Vol.342, p.122526-122526, Article 122526

2024

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The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer

Experimental and Molecular Medicine, 2024, 56(0), , pp.220-234

2024

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Tumor regionalization after surgery: Roles of the tumor microenvironment and neutrophil extracellular traps

Experimental and Molecular Medicine, 2022, 54(0), , pp.720-729

2022

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Human Placenta‐Derived Mesenchymal Stem Cells Promote Hepatic Regeneration in CCl4‐Injured Rat Liver Model via Increased Autophagic Mechanism

Stem cells (Dayton, Ohio), 2013-08, Vol.31 (8), p.1584-1596

2013

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Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway

Oncogene, 2018-06, Vol.37 (23), p.3070-3087

2018

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Histone demethylase PHF2 activates CREB and promotes memory consolidation

EMBO reports, 2019-09, Vol.20 (9), p.e45907-n/a

2019

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Deficiency of H3K79 Histone Methyltransferase Dot1-like Protein (DOT1L) Inhibits Cell Proliferation

The Journal of biological chemistry, 2012-02, Vol.287 (8), p.5588-5599

2012

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Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1

Scientific reports, 2020-10, Vol.10 (1), p.18210-18210, Article 18210

2020

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IL-25 as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis

Journal of allergy and clinical immunology, 2015-06, Vol.135 (6), p.1476-1485.e7

2015

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FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes

Cancer research (Chicago, Ill.), 2018-03, Vol.78 (5), p.1184-1199

2018

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Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

Nature communications, 2023-10, Vol.14 (1), p.6370-6370, Article 6370

2023

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Bone morphogenetic protein-2 as a novel biomarker for refractory chronic rhinosinusitis with nasal polyps

Journal of allergy and clinical immunology, 2021-08, Vol.148 (2), p.461-472.e13

2021

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Nuclear FGFR2 negatively regulates hypoxia-induced cell invasion in prostate cancer by interacting with HIF-1 and HIF-2

Scientific reports, 2019-03, Vol.9 (1), p.3480-3480, Article 3480

2019

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A novel HIF1AN substrate KANK3 plays a tumor‐suppressive role in hepatocellular carcinoma

Cell biology international, 2018-03, Vol.42 (3), p.303-312

2018

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Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression

Scientific reports, 2018-04, Vol.8 (1), p.6201-12, Article 6201

2018

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Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development

Nature communications, 2023-04, Vol.14 (1), p.2363-2363, Article 2363

2023

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Hypoxia-driven epigenetic regulation in cancer progression: A focus on histone methylation and its modifying enzymes

Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer

Cervical cancer is addicted to SIRT1 disarming the AIM2 antiviral defense

Fatty-acid-induced FABP5/HIF-1 reprograms lipid metabolism and enhances the proliferation of liver cancer cells

Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway

Loss of EGR3 is an independent risk factor for metastatic progression in prostate cancer

SIRT1 and AMPK Mediate Hypoxia-Induced Resistance of Non―Small Cell Lung Cancers to Cisplatin and Doxorubicin

The E3 ligase C-CBL inhibits cancer cell migration by neddylating the proto-oncogene c-Src

Oxygen sensor FIH inhibits HACE1-dependent ubiquitination of Rac1 to enhance metastatic potential in breast cancer cells

Development of a rectally administrable Dnase1 to treat septic shock by targeting NETs

The polyol pathway and nuclear ketohexokinase A signaling drive hyperglycemia-induced metastasis of gastric cancer

Tumor regionalization after surgery: Roles of the tumor microenvironment and neutrophil extracellular traps

Human Placenta‐Derived Mesenchymal Stem Cells Promote Hepatic Regeneration in CCl4‐Injured Rat Liver Model via Increased Autophagic Mechanism

Astrocyte-derived CCL20 reinforces HIF-1-mediated hypoxic responses in glioblastoma by stimulating the CCR6-NF-κB signaling pathway

Histone demethylase PHF2 activates CREB and promotes memory consolidation

Deficiency of H3K79 Histone Methyltransferase Dot1-like Protein (DOT1L) Inhibits Cell Proliferation

Neddylation blockade induces HIF-1α driven cancer cell migration via upregulation of ZEB1

IL-25 as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis

FIH Is an Oxygen Sensor in Ovarian Cancer for G9a/GLP-Driven Epigenetic Regulation of Metastasis-Related Genes

Palmitoylation-driven PHF2 ubiquitination remodels lipid metabolism through the SREBP1c axis in hepatocellular carcinoma

Bone morphogenetic protein-2 as a novel biomarker for refractory chronic rhinosinusitis with nasal polyps

Nuclear FGFR2 negatively regulates hypoxia-induced cell invasion in prostate cancer by interacting with HIF-1 and HIF-2

A novel HIF1AN substrate KANK3 plays a tumor‐suppressive role in hepatocellular carcinoma

Wogonin attenuates nasal polyp formation by inducing eosinophil apoptosis through HIF-1α and survivin suppression

Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development

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