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FXR in liver physiology: Multiple faces to regulate liver metabolism

Biochimica et biophysica acta. Molecular basis of disease, 2021-07, Vol.1867 (7), p.166133, Article 166133

2021

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Meta‐analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions

Hepatology communications, 2021-10, Vol.5 (10), p.1721-1736

2021

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Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy

Biochimica et biophysica acta. Molecular basis of disease, 2021-02, Vol.1867 (2), p.166017-166017, Article 166017

2021

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Recent advances on FXR-targeting therapeutics

Molecular and cellular endocrinology, 2022-07, Vol.552, p.111678-111678, Article 111678

2022

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Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention

Expert opinion on therapeutic targets, 2019-03, Vol.23 (3), p.177-186

2019

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MicroRNA-182-5p regulates hedgehog signaling pathway and chemosensitivity of cisplatin-resistant lung adenocarcinoma cells via targeting GLI2

Cancer letters, 2020-01, Vol.469, p.266-276

2020

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FXR binding and transcription in the liver is signficantly altered in obese patients with NAFLD

Journal of hepatology, 2022-07, Vol.77, p.S696-S697

2022

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FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis

Journal of hepatology, 2020-06, Vol.72 (6), p.1122-1131

2020

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Obeticholic acid may increase the risk of gallstone formation in susceptible patients

Journal of hepatology, 2019-11, Vol.71 (5), p.986-991

2019

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Targeting organ-specific mitochondrial dysfunction to improve biological aging

Pharmacology & therapeutics (Oxford), 2024-10, Vol.262, p.108710, Article 108710

2024

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Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA

Gastroenterology (New York, N.Y. 1943), 2007, Vol.132 (1), p.330-342

2007

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Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor

Laboratory investigation, 2021-10, Vol.101 (10), p.1394-1402

2021

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Hepatic farnesoid X receptor is necessary to facilitate ductular reaction and expression of heme biosynthetic genes

Hepatology communications, 2023-10, Vol.7 (10)

2023

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Metabolomic Profiling Reveals Potential Markers and Bioprocesses Altered in Bladder Cancer Progression

Cancer research (Chicago, Ill.), 2011-12, Vol.71 (24), p.7376-7386

2011

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RF03 | PMON288 Determining Mechanisms of Farnesoid×Receptor Regulation of Heme Biosynthesis and Ductular Reaction

Journal of the Endocrine Society, 2022-11, Vol.6 (Supplement_1), p.A730-A731

2022

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Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1 PR 2, ERK and SF ‐1

Liver international, 2019-11, Vol.39 (11), p.2112-2123

2019

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Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF‐1

Liver international, 2019-11, Vol.39 (11), p.2112-2123

2019

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Liver receptor homolog‐1 is a critical determinant of methyl‐pool metabolism

Hepatology (Baltimore, Md.), 2016-01, Vol.63 (1), p.95-106

2016

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Metabolomic Profiling Identifies Biochemical Pathways Associated with Castration-Resistant Prostate Cancer

Journal of proteome research, 2014-02, Vol.13 (2), p.1088-1100

2014

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Investigating the Role of Farnesoid X Receptor in Heme Biosynthesis and Ductular Reaction

Journal of the Endocrine Society, 2021-05, Vol.5 (Supplement_1), p.A810-A811

2021

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Patients with coronary heart disease, dilated cardiomyopathy and idiopathic ventricular tachycardia share overlapping patterns of pathogenic variation in cardiac risk genes

PeerJ (San Francisco, CA), 2021-01, Vol.9, p.e10711-e10711, Article e10711

2021

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LRH-1 is a critical determinant of methyl-pool metabolism

Hepatology (Baltimore, Md.), 2015-10, Vol.63 (1), p.95-106

2015

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Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor

Laboratory investigation, 2021-10, Vol.101 (10), p.1394

2021

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Abstract 1056: Inhibition of hexose monophosphate pathway promotes castration resistant prostate cancer

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.1056-1056

2016

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FXR in liver physiology: Multiple faces to regulate liver metabolism

Inhibition of the hexosamine biosynthetic pathway promotes castration-resistant prostate cancer

Meta‐analysis and Consolidation of Farnesoid X Receptor Chromatin Immunoprecipitation Sequencing Data Across Different Species and Conditions

Regulation of autophagy by bile acids and in cholestasis - CholestoPHAGY or CholeSTOPagy

Recent advances on FXR-targeting therapeutics

Involvement of long non-coding RNA HULC (highly up-regulated in liver cancer) in pathogenesis and implications for therapeutic intervention

MicroRNA-182-5p regulates hedgehog signaling pathway and chemosensitivity of cisplatin-resistant lung adenocarcinoma cells via targeting GLI2

FXR binding and transcription in the liver is signficantly altered in obese patients with NAFLD

FXR-dependent Rubicon induction impairs autophagy in models of human cholestasis

Obeticholic acid may increase the risk of gallstone formation in susceptible patients

Targeting organ-specific mitochondrial dysfunction to improve biological aging

Characterization of HULC, a Novel Gene With Striking Up-Regulation in Hepatocellular Carcinoma, as Noncoding RNA

Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor

Hepatic farnesoid X receptor is necessary to facilitate ductular reaction and expression of heme biosynthetic genes

Metabolomic Profiling Reveals Potential Markers and Bioprocesses Altered in Bladder Cancer Progression

RF03 | PMON288 Determining Mechanisms of Farnesoid×Receptor Regulation of Heme Biosynthesis and Ductular Reaction

Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1 PR 2, ERK and SF ‐1

Bile acids increase steroidogenesis in cholemic mice and induce cortisol secretion in adrenocortical H295R cells via S1PR2, ERK and SF‐1

Liver receptor homolog‐1 is a critical determinant of methyl‐pool metabolism

Metabolomic Profiling Identifies Biochemical Pathways Associated with Castration-Resistant Prostate Cancer

Investigating the Role of Farnesoid X Receptor in Heme Biosynthesis and Ductular Reaction

Patients with coronary heart disease, dilated cardiomyopathy and idiopathic ventricular tachycardia share overlapping patterns of pathogenic variation in cardiac risk genes

LRH-1 is a critical determinant of methyl-pool metabolism

Bile acid-induced tissue factor activity in hepatocytes correlates with activation of farnesoid X receptor

Abstract 1056: Inhibition of hexose monophosphate pathway promotes castration resistant prostate cancer

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