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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies

Scientific reports, 2015-07, Vol.5 (1), p.12007-12007, Article 12007

2015

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PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription

Biochemical Society transactions, 2007-12, Vol.35 (Pt 6), p.1405-1408

Palvimo, J J

2007

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Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Nucleic acids research, 2024-01, Vol.52 (2), p.625-642

2024

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Steroid up-regulation of FKBP51 and its role in hormone signaling

Current opinion in pharmacology, 2011-08, Vol.11 (4), p.326-331

2011

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RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

Nature cell biology, 2008-05, Vol.10 (5), p.538-546

2008

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SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

Nucleic acids research, 2021-02, Vol.49 (4), p.1951-1971

2021

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PDSM, a Motif for Phosphorylation-Dependent SUMO Modification

Proceedings of the National Academy of Sciences - PNAS, 2006-01, Vol.103 (1), p.45-50

2006

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Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

Nature communications, 2019-02, Vol.10 (1), p.777-777, Article 777

2019

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SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner

Nucleic acids research, 2014-07, Vol.42 (13), p.8310-8319

2014

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PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases

Molecular and Cellular Biology, 2002-07, Vol.22 (14), p.5222-5234

2002

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The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation

EMBO reports, 2021-12, Vol.22 (12), p.e52764-n/a

2021

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Circadian Clock Control by SUMOylation of BMAL1

Science (American Association for the Advancement of Science), 2005-08, Vol.309 (5739), p.1390-1394

2005

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Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Molecular & cellular proteomics, 2017-08, Vol.16 (8), p.1462-1474

2017

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Covalent Modification of the Androgen Receptor by Small Ubiquitin-Like Modifier 1 (SUMO-1)

Proceedings of the National Academy of Sciences - PNAS, 2000-12, Vol.97 (26), p.14145-14150

2000

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Glucocorticoid Receptor Activates Poised FKBP51 Locus through Long-Distance Interactions

Molecular endocrinology (Baltimore, Md.), 2010-03, Vol.24 (3), p.511-525

2010

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Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

Scientific reports, 2016-09, Vol.6 (1), p.32819-32819, Article 32819

2016

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Phosphorylation of Serine 303 Is a Prerequisite for the Stress-Inducible SUMO Modification of Heat Shock Factor 1

Molecular and Cellular Biology, 2003-04, Vol.23 (8), p.2953-2968

2003

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A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

EMBO molecular medicine, 2024-09, Vol.16 (10), p.2485-2515

2024

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Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

Molecular and Cellular Biology, 2003-12, Vol.23 (23), p.8563-8575

2003

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Coregulator Recruitment and Histone Modifications in Transcriptional Regulation by the Androgen Receptor

Molecular endocrinology (Baltimore, Md.), 2004-11, Vol.18 (11), p.2633-2648

2004

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Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein

American journal of human genetics, 2000-02, Vol.66 (2), p.378-392

2000

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IRF2BP2 modulates the crosstalk between glucocorticoid and TNF signaling

The Journal of steroid biochemistry and molecular biology, 2019-09, Vol.192, p.105382-105382, Article 105382

2019

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Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Scientific reports, 2016-09, Vol.6 (1), p.33510-33510, Article 33510

2016

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Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex

The Journal of biological chemistry, 2002-12, Vol.277 (50), p.48366-48371

2002

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Genome-wide crosstalk between steroid receptors in breast and prostate cancers

Endocrine-related cancer, 2021-09, Vol.28 (9), p.R231-R250

2021

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Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies

PIAS proteins as regulators of small ubiquitin-related modifier (SUMO) modifications and transcription

Chromatin accessibility and pioneer factor FOXA1 restrict glucocorticoid receptor action in prostate cancer

Steroid up-regulation of FKBP51 and its role in hormone signaling

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites

PDSM, a Motif for Phosphorylation-Dependent SUMO Modification

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction

SUMOylation modulates the transcriptional activity of androgen receptor in a target gene and pathway selective manner

PIAS Proteins Modulate Transcription Factors by Functioning as SUMO-1 Ligases

The androgen receptor depends on ligand-binding domain dimerization for transcriptional activation

Circadian Clock Control by SUMOylation of BMAL1

Agonist-specific Protein Interactomes of Glucocorticoid and Androgen Receptor as Revealed by Proximity Mapping

Covalent Modification of the Androgen Receptor by Small Ubiquitin-Like Modifier 1 (SUMO-1)

Glucocorticoid Receptor Activates Poised FKBP51 Locus through Long-Distance Interactions

Complete androgen insensitivity syndrome caused by a deep intronic pseudoexon-activating mutation in the androgen receptor gene

Phosphorylation of Serine 303 Is a Prerequisite for the Stress-Inducible SUMO Modification of Heat Shock Factor 1

A critical role for HNF4α in polymicrobial sepsis-associated metabolic reprogramming and death

Acetylation of Androgen Receptor Enhances Coactivator Binding and Promotes Prostate Cancer Cell Growth

Coregulator Recruitment and Histone Modifications in Transcriptional Regulation by the Androgen Receptor

Mutations in the AIRE Gene: Effects on Subcellular Location and Transactivation Function of the Autoimmune Polyendocrinopathy-Candidiasis–Ectodermal Dystrophy Protein

IRF2BP2 modulates the crosstalk between glucocorticoid and TNF signaling

Global analysis of transcription in castration-resistant prostate cancer cells uncovers active enhancers and direct androgen receptor targets

Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex

Genome-wide crosstalk between steroid receptors in breast and prostate cancers

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