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Optimal T-cell receptor affinity for inducing autoimmunity

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.17248-17253

2014

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Massive immune response against IVIg interferes with response against other antigens in mice: A new mode of action?

PloS one, 2017-10, Vol.12 (10), p.e0186046-e0186046

2017

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Signaling Life and Death in the Thymus: Timing Is Everything

Science (American Association for the Advancement of Science), 2003-03, Vol.299 (5614), p.1859-1863

2003

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Lck Regulates the Threshold of Activation in Primary T Cells, While both Lck and Fyn Contribute to the Magnitude of the Extracellular Signal-Related Kinase Response

Molecular and Cellular Biology, 2006-11, Vol.26 (22), p.8655-8665

2006

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Small molecule inhibition of Csk alters affinity recognition by T cells

eLife, 2015-08, Vol.4

2015

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Negative selection - clearing out the bad apples from the T-cell repertoire

Nature reviews. Immunology, 2003-05, Vol.3 (5), p.383-391

Palmer, Ed

2003

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Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla

PloS one, 2012-12, Vol.7 (12), p.e52591-e52591

2012

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Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper

Nature reviews. Immunology, 2009-03, Vol.9 (3), p.207-213

2009

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Trials in pandemics: here we go again?

British journal of anaesthesia : BJA, 2021-01, Vol.126 (1), p.e42-e44

2021

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Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

The Journal of immunology (1950), 2000-08, Vol.165 (4), p.2068-2076

2000

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Opposing effects of actin signaling and LFA‐1 on establishing the affinity threshold for inducing effector T‐cell responses in mice

European journal of immunology, 2016-08, Vol.46 (8), p.1887-1901

2016

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What is the role of autoimmunity in type 1 diabetes? A clinical perspective

Diabetologia, 2014-04, Vol.57 (4), p.653-655

2014

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T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

Immunity (Cambridge, Mass.), 2012-10, Vol.37 (4), p.709-720

2012

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The T-cell receptor signalosome: a dynamic structure with expanding complexity

Current Opinion in Immunology, 2002-06, Vol.14 (3), p.299-305

2002

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TCR signaling requirements for activating T cells and for generating memory

Cellular and molecular life sciences : CMLS, 2012-05, Vol.69 (10), p.1565-1575

2012

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Affinity for self antigen selects Treg cells with distinct functional properties

Nature immunology, 2016-09, Vol.17 (9), p.1093-1101

2016

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Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance

Cell, 2014-10, Vol.159 (2), p.333-345

2014

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Allograft Rejection in a New Allospecific CD4+ TCR Transgenic Mouse

American journal of transplantation, 2003-04, Vol.3 (4), p.381-389

2003

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The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8αα+ Intraepithelial Lymphocyte Development

Immunity (Cambridge, Mass.), 2014-08, Vol.41 (2), p.230-243

2014

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Effects of self-rated health on sick leave, disability pension, hospital admissions and mortality. A population-based longitudinal study of nearly 15,000 observations among Swedish women and men

BMC public health, 2012-12, Vol.12 (1), p.1103-1103, Article 1103

2012

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The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8 alpha alpha + Intraepithelial Lymphocyte Development

Immunity (Cambridge, Mass.), 2014-08, Vol.41 (2), p.230-243

2014

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Signaling in thymic selection

Current opinion in immunology, 2011-04, Vol.23 (2), p.207-212

2011

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Inability to Induce Tolerance Through Direct Antigen Presentation

American journal of transplantation, 2002-07, Vol.2 (6), p.510-519

2002

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Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Nature, 2006-12, Vol.444 (7120), p.724-729

2006

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Different T Cell Receptor Signals Determine CD8⁺ Memory Versus Effector Development

Science (American Association for the Advancement of Science), 2009-01, Vol.323 (5913), p.502-505

2009

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Optimal T-cell receptor affinity for inducing autoimmunity

Massive immune response against IVIg interferes with response against other antigens in mice: A new mode of action?

Signaling Life and Death in the Thymus: Timing Is Everything

Lck Regulates the Threshold of Activation in Primary T Cells, While both Lck and Fyn Contribute to the Magnitude of the Extracellular Signal-Related Kinase Response

Small molecule inhibition of Csk alters affinity recognition by T cells

Negative selection - clearing out the bad apples from the T-cell repertoire

Antigen recognition by autoreactive CD4⁺ thymocytes drives homeostasis of the thymic medulla

Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper

Trials in pandemics: here we go again?

Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function

Opposing effects of actin signaling and LFA‐1 on establishing the affinity threshold for inducing effector T‐cell responses in mice

What is the role of autoimmunity in type 1 diabetes? A clinical perspective

T Cell Affinity Regulates Asymmetric Division, Effector Cell Differentiation, and Tissue Pathology

The T-cell receptor signalosome: a dynamic structure with expanding complexity

TCR signaling requirements for activating T cells and for generating memory

Affinity for self antigen selects Treg cells with distinct functional properties

Coreceptor Scanning by the T Cell Receptor Provides a Mechanism for T Cell Tolerance

Allograft Rejection in a New Allospecific CD4+ TCR Transgenic Mouse

The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8αα+ Intraepithelial Lymphocyte Development

Effects of self-rated health on sick leave, disability pension, hospital admissions and mortality. A population-based longitudinal study of nearly 15,000 observations among Swedish women and men

The Transcription Factor T-bet Is Induced by IL-15 and Thymic Agonist Selection and Controls CD8 alpha alpha + Intraepithelial Lymphocyte Development

Signaling in thymic selection

Inability to Induce Tolerance Through Direct Antigen Presentation

Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling

Different T Cell Receptor Signals Determine CD8⁺ Memory Versus Effector Development

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