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FDA Approval Summary: Pralsetinib for the Treatment of Lung and Thyroid Cancers With RET Gene Mutations or Fusions

Clinical cancer research, 2021-10, Vol.27 (20), p.5452-5456

2021

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FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC

Clinical cancer research, 2022-06, Vol.28 (11), p.2221-2228

2022

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Expansion Cohorts in First-in-Human Solid Tumor Oncology Trials

Clinical cancer research, 2015-10, Vol.21 (20), p.4545-4551

2015

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Treatment of advanced solid tumors with immunotoxin LMB-1: An antibody linked to Pseudomonas exotoxin

Nature medicine, 1996-03, Vol.2 (3), p.350-353

1996

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Hepatotoxicity in Cancer Patients Receiving erb-38, a Recombinant Immunotoxin That Targets the erbB2 Receptor

Clinical cancer research, 1999-09, Vol.5 (9), p.2311-2315

1999

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Immunotoxin therapy for cancer

JAMA : the journal of the American Medical Association, 1993-01, Vol.269 (1), p.78

1993

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Antitumor activity and pharmacokinetics in mice of a recombinant immunotoxin containing a disulfide-stabilized Fv fragment

Cancer research (Chicago, Ill.), 1994-05, Vol.54 (10), p.2714-2718

1994

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Monoclonal antibody MRK16 reverses the multidrug resistance of multidrug-resistant transgenic mice

Cancer research (Chicago, Ill.), 1992-08, Vol.52 (16), p.4427-4432

1992

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Inhibition of antibody response to Pseudomonas exotoxin and an immunotoxin containing Pseudomonas exotoxin by 15-deoxyspergualin in mice

Cancer research (Chicago, Ill.), 1990-12, Vol.50 (24), p.7750-7753

1990

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Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer

Journal of clinical oncology, 1991-12, Vol.9 (12), p.2095-2103

1991

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FDA subset analysis of the safety of nivolumab in elderly patients with advanced cancers

Journal of clinical oncology, 2016-05, Vol.34 (15_suppl), p.10010-10010

2016

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Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys

Cancer research (Chicago, Ill.), 1992-06, Vol.52 (11), p.3189

1992

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Alteration of a Protease-Sensitive Region of Pseudomonas Exotoxin Prolongs its Survival in the Circulation of Mice

Proceedings of the National Academy of Sciences - PNAS, 1992-04, Vol.89 (7), p.3065-3069

1992

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B3(Fv)-PE38KDEL, A Single-Chain Immunotoxin that Causes Complete Regression of a Human Carcinoma in Mice

Proceedings of the National Academy of Sciences - PNAS, 1991-10, Vol.88 (19), p.8616-8620

1991

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Transforming growth factor-β1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer

Clinical cancer research, 1995, Vol.1 (1), p.129-136

1995

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Evaluation of the Serum Stability and In Vivo Biodistribution of CHX-DTPA and Other Ligands for Yttrium Labeling of Monoclonal Antibodies

The Journal of nuclear medicine (1978), 1994-05, Vol.35 (5), p.882-889

1994

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Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome

Clinical cancer research, 1995-12, Vol.1 (12), p.1589-1594

1995

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Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma

The American journal of surgical pathology, 1992-03, Vol.16 (3), p.259-268

1992

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Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium

Cancer research (Chicago, Ill.), 1992, Vol.52 (1), p.181-186

1992

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Administration of disulfide‐stabilized Fv‐immunotoxins B1(dsFv)‐PE38 and B3(dsFv)‐PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice

International journal of cancer, 1995-07, Vol.62 (3), p.351-355

1995

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Identification of epitopes on a mutant form of Pseudomonas exotoxin using serum from humans treated with Pseudomonas exotoxin containing immunotoxins

European journal of immunology, 1997-06, Vol.27 (6), p.1459-1468

1997

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Recombinant Toxins: New Therapeutic Agents for Cancer

Annals of the New York Academy of Sciences, 1995-06, Vol.758 (1), p.345-354

1995

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Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells

Journal of neurosurgery, 1993-10, Vol.79 (4), p.569

1993

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Anti-Tumor Activities of Immunotoxins Made of Monoclonal Antibody B3 and Various Forms of Pseudomonas Exotoxin

Proceedings of the National Academy of Sciences - PNAS, 1991-04, Vol.88 (8), p.3358-3362

1991

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Intrathecal Administration of Single-Chain Immunotoxin, LMB-7 [B3(Fv)- PE38], Produces Cures of Carcinomatous Meningitis in a Rat Model

Proceedings of the National Academy of Sciences - PNAS, 1995-03, Vol.92 (7), p.2765-2769

1995

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FDA Approval Summary: Pralsetinib for the Treatment of Lung and Thyroid Cancers With RET Gene Mutations or Fusions

FDA Approval Summary: Pembrolizumab, Atezolizumab, and Cemiplimab-rwlc as Single Agents for First-Line Treatment of Advanced/Metastatic PD-L1-High NSCLC

Expansion Cohorts in First-in-Human Solid Tumor Oncology Trials

Treatment of advanced solid tumors with immunotoxin LMB-1: An antibody linked to Pseudomonas exotoxin

Hepatotoxicity in Cancer Patients Receiving erb-38, a Recombinant Immunotoxin That Targets the erbB2 Receptor

Immunotoxin therapy for cancer

Antitumor activity and pharmacokinetics in mice of a recombinant immunotoxin containing a disulfide-stabilized Fv fragment

Monoclonal antibody MRK16 reverses the multidrug resistance of multidrug-resistant transgenic mice

Inhibition of antibody response to Pseudomonas exotoxin and an immunotoxin containing Pseudomonas exotoxin by 15-deoxyspergualin in mice

Clinical evaluation of intraperitoneal Pseudomonas exotoxin immunoconjugate OVB3-PE in patients with ovarian cancer

FDA subset analysis of the safety of nivolumab in elderly patients with advanced cancers

Antitumor effects of B3-PE and B3-LysPE40 in a nude mouse model of human breast cancer and the evaluation of B3-PE toxicity in monkeys

Alteration of a Protease-Sensitive Region of Pseudomonas Exotoxin Prolongs its Survival in the Circulation of Mice

B3(Fv)-PE38KDEL, A Single-Chain Immunotoxin that Causes Complete Regression of a Human Carcinoma in Mice

Transforming growth factor-β1 circulates in normal human plasma and is unchanged in advanced metastatic breast cancer

Evaluation of the Serum Stability and In Vivo Biodistribution of CHX-DTPA and Other Ligands for Yttrium Labeling of Monoclonal Antibodies

Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome

Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma

Characterization of the antigen (CAK1) recognized by monoclonal antibody K1 present on ovarian cancers and normal mesothelium

Administration of disulfide‐stabilized Fv‐immunotoxins B1(dsFv)‐PE38 and B3(dsFv)‐PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice

Identification of epitopes on a mutant form of Pseudomonas exotoxin using serum from humans treated with Pseudomonas exotoxin containing immunotoxins

Recombinant Toxins: New Therapeutic Agents for Cancer

Cytotoxicity and antitumor effects of growth factor-toxin fusion proteins on human glioblastoma multiforme cells

Anti-Tumor Activities of Immunotoxins Made of Monoclonal Antibody B3 and Various Forms of Pseudomonas Exotoxin

Intrathecal Administration of Single-Chain Immunotoxin, LMB-7 [B3(Fv)- PE38], Produces Cures of Carcinomatous Meningitis in a Rat Model

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