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Efficient rational modification of non-ribosomal peptides by adenylation domain substitution

Nature communications, 2020-09, Vol.11 (1), p.4554-4554, Article 4554

2020

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Structural, functional and evolutionary perspectives on effective re-engineering of non-ribosomal peptide synthetase assembly lines

Natural product reports, 2018-11, Vol.35 (11), p.121-1228

2018

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Uncovering the biosynthetic potential of rare metagenomic DNA using co-occurrence network analysis of targeted sequences

Nature communications, 2019-08, Vol.10 (1), p.3848-9, Article 3848

2019

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Chemical-biogeographic survey of secondary metabolism in soil

Proceedings of the National Academy of Sciences - PNAS, 2014-03, Vol.111 (10), p.3757-3762

2014

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Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (29), p.11797-11802

2013

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Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (14), p.4221-4226

2015

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Biosynthesis of novel Pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa

Applied and Environmental Microbiology, 2014-09, Vol.80 (18), p.5723-5731

2014

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Generating Functional Recombinant NRPS Enzymes in the Laboratory Setting via Peptidyl Carrier Protein Engineering

Cell chemical biology, 2016-11, Vol.23 (11), p.1395-1406

2016

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Global biogeographic sampling of bacterial secondary metabolism

eLife, 2015-01, Vol.4, p.e05048-e05048

2015

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Targeted Isolation of Rubrolides from the New Zealand Marine Tunicate Synoicum kuranui

Marine drugs, 2020-06, Vol.18 (7), p.337

2020

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Characterization of pyoverdine and achromobactin in Pseudomonas syringae pv. phaseolicola 1448a

BMC microbiology, 2011-10, Vol.11 (1), p.218-218

2011

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Rapid and flexible biochemical assays for evaluating 4'-phosphopantetheinyl transferase activity

Biochemical journal, 2011-06, Vol.436 (3), p.709-717

2011

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Secondary metabolism in the lichen symbiosis

Chemical Society reviews, 2018-03, Vol.47 (5), p.173-176

2018

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Inhibition of Indigoidine Synthesis as a High-Throughput Colourimetric Screen for Antibiotics Targeting the Essential Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT

Pharmaceutics, 2021-07, Vol.13 (7), p.1066

2021

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A Genomic Survey of the Natural Product Biosynthetic Potential of Actinomycetes Isolated from New Zealand Lichens

mSystems, 2023-04, Vol.8 (2), p.e0103022-e0103022

2023

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Calcium-Dependent Lipopeptide Antibiotics against Drug-Resistant Pathogens Discovered via Host-Dependent Heterologous Expression of a Cloned Biosynthetic Gene Cluster

Angewandte Chemie International Edition, 2024-08, p.e202410286

2024

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Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens

Nature microbiology, 2018-04, Vol.3 (4), p.415-422

2018

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Skyllamycins D and E, Non-Ribosomal Cyclic Depsipeptides from Lichen-Sourced Streptomyces anulatus

Journal of natural products (Washington, D.C.), 2021-09, Vol.84 (9), p.2536-2543

2021

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Directed Evolution of the BpsA Carrier Protein Domain for Recognition by Non-cognate 4'-Phosphopantetheinyl Transferases to Enable Inhibitor Screening

Methods in molecular biology (Clifton, N.J.), 2023, Vol.2670, p.145

2023

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Stictamycin, an Aromatic Polyketide Antibiotic Isolated from a New Zealand Lichen-Sourced Streptomyces Species

Journal of natural products (Washington, D.C.), 2023-03, Vol.86 (3), p.526-532

2023

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Preparation of Soil Metagenome Libraries and Screening for Gene-Specific Amplicons

Methods in molecular biology (Clifton, N.J.), 2022, Vol.2397, p.3

2022

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Metagenomic Exploration of the Marine Sponge Mycale hentscheli Uncovers Multiple Polyketide-Producing Bacterial Symbionts

mBio, 2020-03, Vol.11 (2)

2020

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Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides

Nature chemical biology, 2024-02, Vol.20 (2), p.251-260

2024

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Metagenome Driven Discovery of Nonribosomal Peptides

ACS chemical biology, 2019-10, Vol.14 (10), p.2115-2126, Article acschembio.9b00618

2019

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Marine Invertebrate Natural Products that Target Microtubules

Journal of natural products (Washington, D.C.), 2018-03, Vol.81 (3), p.691-702

2018

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Efficient rational modification of non-ribosomal peptides by adenylation domain substitution

Structural, functional and evolutionary perspectives on effective re-engineering of non-ribosomal peptide synthetase assembly lines

Uncovering the biosynthetic potential of rare metagenomic DNA using co-occurrence network analysis of targeted sequences

Chemical-biogeographic survey of secondary metabolism in soil

Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products

Multiplexed metagenome mining using short DNA sequence tags facilitates targeted discovery of epoxyketone proteasome inhibitors

Biosynthesis of novel Pyoverdines by domain substitution in a nonribosomal peptide synthetase of Pseudomonas aeruginosa

Generating Functional Recombinant NRPS Enzymes in the Laboratory Setting via Peptidyl Carrier Protein Engineering

Global biogeographic sampling of bacterial secondary metabolism

Targeted Isolation of Rubrolides from the New Zealand Marine Tunicate Synoicum kuranui

Characterization of pyoverdine and achromobactin in Pseudomonas syringae pv. phaseolicola 1448a

Rapid and flexible biochemical assays for evaluating 4'-phosphopantetheinyl transferase activity

Secondary metabolism in the lichen symbiosis

Inhibition of Indigoidine Synthesis as a High-Throughput Colourimetric Screen for Antibiotics Targeting the Essential Mycobacterium tuberculosis Phosphopantetheinyl Transferase PptT

A Genomic Survey of the Natural Product Biosynthetic Potential of Actinomycetes Isolated from New Zealand Lichens

Calcium-Dependent Lipopeptide Antibiotics against Drug-Resistant Pathogens Discovered via Host-Dependent Heterologous Expression of a Cloned Biosynthetic Gene Cluster

Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens

Skyllamycins D and E, Non-Ribosomal Cyclic Depsipeptides from Lichen-Sourced Streptomyces anulatus

Directed Evolution of the BpsA Carrier Protein Domain for Recognition by Non-cognate 4'-Phosphopantetheinyl Transferases to Enable Inhibitor Screening

Stictamycin, an Aromatic Polyketide Antibiotic Isolated from a New Zealand Lichen-Sourced Streptomyces Species

Preparation of Soil Metagenome Libraries and Screening for Gene-Specific Amplicons

Metagenomic Exploration of the Marine Sponge Mycale hentscheli Uncovers Multiple Polyketide-Producing Bacterial Symbionts

Metagenomic domain substitution for the high-throughput modification of nonribosomal peptides

Metagenome Driven Discovery of Nonribosomal Peptides

Marine Invertebrate Natural Products that Target Microtubules

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