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Tracking the Dynamic Folding and Unfolding of RNA G‐Quadruplexes in Live Cells

Angewandte Chemie (International ed.), 2018-04, Vol.57 (17), p.4702-4706

International ed. in English, 2018

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Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid⁻Protein Interaction

Molecules (Basel, Switzerland), 2019-01, Vol.24 (3), p.396

2019

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Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole

Nucleic acids research, 2017-02, Vol.45 (4), p.1606

2017

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Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c‑MYC Transcription Inhibitor Specifically Targeting the Promoter G‑Quadruplex

Journal of medicinal chemistry, 2018-03, Vol.61 (6), p.2447-2459

2018

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Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer

Nucleic acids research, 2022-02, Vol.50 (4), p.1829

2022

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G-Quadruplexes: Targets in Anticancer Drug Design

ChemMedChem, 2008-05, Vol.3 (5), p.690-713

2008

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Conformation Selective Antibody Enables Genome Profiling and Leads to Discovery of Parallel G-Quadruplex in Human Telomeres

Cell chemical biology, 2016-10, Vol.23 (10), p.1261-1270

2016

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Discovery of Novel 11-Triazole Substituted Benzofuro[3,2‑b]quinolone Derivatives as c‑myc G‑Quadruplex Specific Stabilizers via Click Chemistry

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5407-5423

2017

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Syntheses and evaluation of new acridone derivatives for selective binding of oncogene c-myc promoter i-motifs in gene transcriptional regulation

Chemical communications (Cambridge, England), 2018, Vol.54 (16), p.2036-2039

2018

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New Disubstituted Quindoline Derivatives Inhibiting Burkitt’s Lymphoma Cell Proliferation by Impeding c‑MYC Transcription

Journal of medicinal chemistry, 2017-07, Vol.60 (13), p.5438-5454

2017

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Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c‑MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.6924-6941

2017

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Design, Synthesis, and Evaluation of Novel p‑(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G‑Quadruplex

Journal of medicinal chemistry, 2018-08, Vol.61 (15), p.6629-6646

2018

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Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes

Chemical communications (Cambridge, England), 2014-01, Vol.50 (81), p.12173-12176

2014

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Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

Chemical communications (Cambridge, England), 2014-01, Vol.50 (52), p.6927-6930

2014

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Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G‑Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Journal of medicinal chemistry, 2015-05, Vol.58 (9), p.3875-3891

2015

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Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: Implications for epigenetic regulation

Biochemical and biophysical research communications, 2013-04, Vol.433 (4), p.368-373

2013

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Synthesis and evaluation of 7-substituted-5,6-dihydrobenzo[c]acridine derivatives as new c-KIT promoter G-quadruplex binding ligands

European journal of medicinal chemistry, 2017-04, Vol.130, p.458-471

2017

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RNA G-Quadruplex: The New Potential Targets for Therapy

Current topics in medicinal chemistry, 2015-01, Vol.15 (19), p.1947

2015

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Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives

Biochimica et biophysica acta, 2014-09, Vol.1840 (9), p.2970-2977

2014

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Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach

Chemical communications (Cambridge, England), 2015-01, Vol.51 (1), p.198-201

2015

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Role of Hairpin-Quadruplex DNA Secondary Structural Conversion in the Promoter of hnRNP K in Gene Transcriptional Regulation

Organic letters, 2015-09, Vol.17 (18), p.4584-4587

2015

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Development of a Universal Colorimetric Indicator for G‑Quadruplex Structures by the Fusion of Thiazole Orange and Isaindigotone Skeleton

Analytical chemistry (Washington), 2012-08, Vol.84 (15), p.6288-6292

2012

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Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

Bioorganic & medicinal chemistry letters, 2009-07, Vol.19 (13), p.3414-3417

2009

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Stabilization of G-Quadruplex DNA and Down-Regulation of Oncogene c-myc by Quindoline Derivatives

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1465-1474

2007

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Facile syntheses of disubstituted bis(vinylquinolinium)benzene derivatives as G-quadruplex DNA binders

Tetrahedron, 2013-06, Vol.69 (24), p.4922-4932

2013

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Tracking the Dynamic Folding and Unfolding of RNA G‐Quadruplexes in Live Cells

Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid⁻Protein Interaction

Specific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole

Discovery of a New Four-Leaf Clover-Like Ligand as a Potent c‑MYC Transcription Inhibitor Specifically Targeting the Promoter G‑Quadruplex

Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer

G-Quadruplexes: Targets in Anticancer Drug Design

Conformation Selective Antibody Enables Genome Profiling and Leads to Discovery of Parallel G-Quadruplex in Human Telomeres

Discovery of Novel 11-Triazole Substituted Benzofuro[3,2‑b]quinolone Derivatives as c‑myc G‑Quadruplex Specific Stabilizers via Click Chemistry

Syntheses and evaluation of new acridone derivatives for selective binding of oncogene c-myc promoter i-motifs in gene transcriptional regulation

New Disubstituted Quindoline Derivatives Inhibiting Burkitt’s Lymphoma Cell Proliferation by Impeding c‑MYC Transcription

Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c‑MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction

Design, Synthesis, and Evaluation of Novel p‑(Methylthio)styryl Substituted Quindoline Derivatives as Neuroblastoma RAS (NRAS) Repressors via Specific Stabilizing the RNA G‑Quadruplex

Discovery of a new fluorescent light-up probe specific to parallel G-quadruplexes

Development of a new colorimetric and red-emitting fluorescent dual probe for G-quadruplex nucleic acids

Discovery of Small Molecules for Up-Regulating the Translation of Antiamyloidogenic Secretase, a Disintegrin and Metalloproteinase 10 (ADAM10), by Binding to the G‑Quadruplex-Forming Sequence in the 5′ Untranslated Region (UTR) of Its mRNA

Stabilization of G-quadruplex DNA by C-5-methyl-cytosine in bcl-2 promoter: Implications for epigenetic regulation

Synthesis and evaluation of 7-substituted-5,6-dihydrobenzo[c]acridine derivatives as new c-KIT promoter G-quadruplex binding ligands

RNA G-Quadruplex: The New Potential Targets for Therapy

Stabilization of VEGF G-quadruplex and inhibition of angiogenesis by quindoline derivatives

Identification of a selective G-quadruplex DNA binder using a multistep virtual screening approach

Role of Hairpin-Quadruplex DNA Secondary Structural Conversion in the Promoter of hnRNP K in Gene Transcriptional Regulation

Development of a Universal Colorimetric Indicator for G‑Quadruplex Structures by the Fusion of Thiazole Orange and Isaindigotone Skeleton

Synthesis and evaluation of 9-O-substituted berberine derivatives containing aza-aromatic terminal group as highly selective telomeric G-quadruplex stabilizing ligands

Stabilization of G-Quadruplex DNA and Down-Regulation of Oncogene c-myc by Quindoline Derivatives

Facile syntheses of disubstituted bis(vinylquinolinium)benzene derivatives as G-quadruplex DNA binders

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