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Vaccines against tuberculosis: where are we and where do we need to go?

PLoS pathogens, 2012-05, Vol.8 (5), p.e1002607-e1002607

2012

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Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

PLoS pathogens, 2016-06, Vol.12 (6), p.e1005687-e1005687

2016

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Prevention of tuberculosis infection and disease by local BCG in repeatedly exposed rhesus macaques

Nature medicine, 2019-02, Vol.25 (2), p.255-262

2019

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A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis -specific T-cell responses in human

Vaccine, 2014-12, Vol.32 (52), p.7098-7107

2014

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Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction

PLoS pathogens, 2019-04, Vol.15 (4), p.e1007724-e1007724

2019

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Host‐directed therapy to combat mycobacterial infections

Immunological reviews, 2021-05, Vol.301 (1), p.62-83

2021

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IgA and IgG against Mycobacterium tuberculosis Rv2031 discriminate between pulmonary tuberculosis patients, Mycobacterium tuberculosis-infected and non-infected individuals

PloS one, 2018-01, Vol.13 (1), p.e0190989-e0190989

2018

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Ebola virus–like particles reprogram cellular metabolism

Journal of molecular medicine (Berlin, Germany), 2023-05, Vol.101 (5), p.557-568

2023

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Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis

The European respiratory journal, 2016-12, Vol.48 (6), p.1751-1763

2016

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New pathways of protective and pathological host defense to mycobacteria

Trends in microbiology (Regular ed.), 2012-09, Vol.20 (9), p.419-428

Ottenhoff, Tom H.M

2012

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A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis

PloS one, 2013-09, Vol.8 (9), p.e73230-e73230

2013

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Composition of the type VII secretion system membrane complex

Molecular microbiology, 2012-10, Vol.86 (2), p.472-484

2012

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Pro- and anti-inflammatory cytokines against Rv2031 are elevated during latent tuberculosis: a study in cohorts of tuberculosis patients, household contacts and community controls in an endemic setting

PloS one, 2015-04, Vol.10 (4), p.e0124134-e0124134

2015

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Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

Journal of Immunology Research, 2016-01, Vol.2016 (2016), p.1-11

2016

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Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

Vaccine, 2010-04, Vol.28 (20), p.3571-3581

2010

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Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

PLoS medicine, 2013-10, Vol.10 (10), p.e1001538-e1001538

2013

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Antigen presentation by MHC-E: a putative target for vaccination?

Trends in immunology, 2022-05, Vol.43 (5), p.355-365

2022

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Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

Proceedings of the National Academy of Sciences - PNAS, 2010-10, Vol.107 (41), p.17686-17691

2010

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Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts

PloS one, 2019-12, Vol.14 (12), p.e0226137-e0226137

2019

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Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection

PloS one, 2009-05, Vol.4 (5), p.e5590-e5590

2009

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Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease

Respirology (Carlton, Vic.), 2018-05, Vol.23 (5), p.455-466

2018

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BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination

Nature communications, 2024-01, Vol.15 (1), p.114-15, Article 114

2024

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Tuberculosis Biomarkers: From Diagnosis to Protection

Infectious disease reports, 2016-06, Vol.8 (2), p.6568

2016

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Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1

Nature, 2007-11, Vol.450 (7170), p.725-730

2007

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Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis

PLoS genetics, 2008-10, Vol.4 (10), p.e1000218-e1000218

2008

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Vaccines against tuberculosis: where are we and where do we need to go?

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment

Prevention of tuberculosis infection and disease by local BCG in repeatedly exposed rhesus macaques

A novel liposomal adjuvant system, CAF01, promotes long-lived Mycobacterium tuberculosis -specific T-cell responses in human

Oxidized low-density lipoprotein (oxLDL) supports Mycobacterium tuberculosis survival in macrophages by inducing lysosomal dysfunction

Host‐directed therapy to combat mycobacterial infections

IgA and IgG against Mycobacterium tuberculosis Rv2031 discriminate between pulmonary tuberculosis patients, Mycobacterium tuberculosis-infected and non-infected individuals

Ebola virus–like particles reprogram cellular metabolism

Correlates of tuberculosis risk: predictive biomarkers for progression to active tuberculosis

New pathways of protective and pathological host defense to mycobacteria

A helicopter perspective on TB biomarkers: pathway and process based analysis of gene expression data provides new insight into TB pathogenesis

Composition of the type VII secretion system membrane complex

Pro- and anti-inflammatory cytokines against Rv2031 are elevated during latent tuberculosis: a study in cohorts of tuberculosis patients, household contacts and community controls in an endemic setting

Characteristics of HLA-E Restricted T-Cell Responses and Their Role in Infectious Diseases

Ag85B–ESAT-6 adjuvanted with IC31® promotes strong and long-lived Mycobacterium tuberculosis specific T cell responses in naïve human volunteers

Detection of tuberculosis in HIV-infected and -uninfected African adults using whole blood RNA expression signatures: a case-control study

Antigen presentation by MHC-E: a putative target for vaccination?

Induction of regulatory T cells by macrophages is dependent on production of reactive oxygen species

Gene expression profiles classifying clinical stages of tuberculosis and monitoring treatment responses in Ethiopian HIV-negative and HIV-positive cohorts

Identification of T-cell antigens specific for latent mycobacterium tuberculosis infection

Update on tuberculosis biomarkers: From correlates of risk, to correlates of active disease and of cure from disease

BCG vaccination-induced acquired control of mycobacterial growth differs from growth control preexisting to BCG vaccination

Tuberculosis Biomarkers: From Diagnosis to Protection

Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1

Genetic association and expression studies indicate a role of toll-like receptor 8 in pulmonary tuberculosis

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