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Distribution of FcRn Across Species and Tissues

The journal of histochemistry and cytochemistry, 2017-06, Vol.65 (6), p.321-333

2017

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Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies

PloS one, 2018-10, Vol.13 (10), p.e0205435-e0205435

2018

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Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

Journal of pharmaceutical sciences, 2017-09, Vol.106 (9), p.2853-2859

2017

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Quantification of IgG monoclonal antibody clearance in tissues

mAbs, 2017-08, Vol.9 (6), p.1007-1015

2017

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Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration

Frontiers in pharmacology, 2022-08, Vol.13, p.958543-958543

2022

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Minipig and Human Metabolism of Aldehyde Oxidase Substrates: In Vitro–In Vivo Comparisons

The AAPS journal, 2017-07, Vol.19 (4), p.1163-1174

2017

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Interstitial IgG antibody pharmacokinetics assessed by combined in vivo‐ and physiologically‐based pharmacokinetic modelling approaches

The Journal of physiology, 2017-12, Vol.595 (24), p.7311-7330

2017

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Pharmacokinetics and Determination of Tumor Interstitial Distribution of a Therapeutic Monoclonal Antibody Using Large-Pore Microdialysis

Journal of pharmaceutical sciences, 2021-08, Vol.110 (8), p.3061-3068

2021

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Nonclinical Pharmacokinetics of Oseltamivir and Oseltamivir Carboxylate in the Central Nervous System

Antimicrobial Agents and Chemotherapy, 2009-11, Vol.53 (11), p.4753-4761

2009

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Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody Distribution

The AAPS journal, 2024-03, Vol.26 (2), p.33-33, Article 33

2024

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Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach

Pharmaceutical research, 2016-10, Vol.33 (10), p.2565-2579

2016

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In vivo Oxidative Metabolism of a Major Peroxidation-Derived DNA Adduct, M₁dG

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6665-6669

2006

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Radiolabeled IgG antibodies: Impact of various labels on neonatal Fc receptor binding

Journal of labelled compounds & radiopharmaceuticals, 2019-09, Vol.62 (11), p.751-757

2019

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High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths

Analytical chemistry (Washington), 2019-03, Vol.91 (5), p.3475-3483

2019

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Erratum to: Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach

Pharmaceutical research, 2016-11, Vol.33 (11), p.2844-2844

2016

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Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms

mAbs, 2017-07, Vol.9 (5), p.781-791

2017

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Role of the intestinal peptide transporter PEPT1 in oseltamivir absorption: in vitro and in vivo studies

Drug metabolism and disposition, 2012-08, Vol.40 (8), p.1556

2012

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Discovery of a factor Xa inhibitor (3 R,4 R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5313-5319

2010

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In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M 1 dG

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6665-6669

2006

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In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M sub(1)dG

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6665-6669

2006

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Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate

Bioorganic & medicinal chemistry letters, 2010-09, Vol.20 (17), p.5313-5319

2010

Volltextzugriff (PDF)

Quantification of IgG monoclonal antibody clearance in tissues

mAbs, 2017, Vol.9 (6), p.1007-1015

2017

Volltextzugriff (PDF)

Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms

mAbs, 2017, Vol.9 (5), p.781-791

2017

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Distribution of FcRn Across Species and Tissues

Nanotracing and cavity-ring down spectroscopy: A new ultrasensitive approach in large molecule drug disposition studies

Tissue Distribution of a Therapeutic Monoclonal Antibody Determined by Large Pore Microdialysis

Quantification of IgG monoclonal antibody clearance in tissues

Investigating brain uptake of a non-targeting monoclonal antibody after intravenous and intracerebroventricular administration

Minipig and Human Metabolism of Aldehyde Oxidase Substrates: In Vitro–In Vivo Comparisons

Interstitial IgG antibody pharmacokinetics assessed by combined in vivo‐ and physiologically‐based pharmacokinetic modelling approaches

Pharmacokinetics and Determination of Tumor Interstitial Distribution of a Therapeutic Monoclonal Antibody Using Large-Pore Microdialysis

Nonclinical Pharmacokinetics of Oseltamivir and Oseltamivir Carboxylate in the Central Nervous System

Biodistribution of Drug/ADA Complexes: The Impact of Immune Complex Formation on Antibody Distribution

Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach

In vivo Oxidative Metabolism of a Major Peroxidation-Derived DNA Adduct, M₁dG

Radiolabeled IgG antibodies: Impact of various labels on neonatal Fc receptor binding

High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths

Erratum to: Characterization of Pharmacokinetics in the Göttingen Minipig with Reference Human Drugs: An In Vitro and In Vivo Approach

Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms

Role of the intestinal peptide transporter PEPT1 in oseltamivir absorption: in vitro and in vivo studies

Discovery of a factor Xa inhibitor (3 R,4 R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-{[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide} as a clinical candidate

In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M 1 dG

In vivo oxidative metabolism of a major peroxidation-derived DNA adduct, M sub(1)dG

Discovery of a factor Xa inhibitor (3R,4R)-1-(2,2-difluoro-ethyl)-pyrrolidine-3,4-dicarboxylic acid 3-[(5-chloro-pyridin-2-yl)-amide] 4-[[2-fluoro-4-(2-oxo-2H-pyridin-1-yl)-phenyl]-amide] as a clinical candidate

Quantification of IgG monoclonal antibody clearance in tissues

Toward in vitro-to-in vivo translation of monoclonal antibody pharmacokinetics: Application of a neonatal Fc receptor-mediated transcytosis assay to understand the interplaying clearance mechanisms

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