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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

Immunity (Cambridge, Mass.), 2016-05, Vol.44 (5), p.1190-1203

2016

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

Cell reports (Cambridge), 2023-05, Vol.42 (5), p.112436-112436, Article 112436

2023

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Siah2 control of T-regulatory cells limits anti-tumor immunity

Nature communications, 2020-01, Vol.11 (1), p.99-99, Article 99

2020

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Striking a Balance-Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic Stimulation

Frontiers in immunology, 2019-07, Vol.10, p.1595-1595

2019

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

Immunity (Cambridge, Mass.), 2016-06, Vol.44 (6), p.1470-1470

2016

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PSGL-1: A New Player in the Immune Checkpoint Landscape

Trends in immunology, 2017-05, Vol.38 (5), p.323-335

2017

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T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival

PloS one, 2011-09, Vol.6 (9), p.e24972-e24972

2011

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CD19 Function in Early and Late B Cell Development: I. Maintenance of Follicular and Marginal Zone B Cells Requires CD19-Dependent Survival Signals

The Journal of immunology (1950), 2003-01, Vol.170 (1), p.73-83

2003

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IRF7-dependent IFN-β production in response to RANKL promotes medullary thymic epithelial cell development

The Journal of immunology (1950), 2013-04, Vol.190 (7), p.3289-3298

2013

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B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel

Blood, 2016-03, Vol.127 (10), p.1276-1286

2016

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MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8 + T Cell Responses

The Journal of immunology (1950), 2022-02, Vol.208 (3), p.603-617

2022

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Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers

The EMBO journal, 2004-10, Vol.23 (21), p.4202-4210

2004

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Alternative and Classical NF-κB Signaling Retain Autoreactive B Cells in the Splenic Marginal Zone and Result in Lupus-like Disease

Immunity (Cambridge, Mass.), 2006-09, Vol.25 (3), p.403-415

2006

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IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling

The Journal of immunology (1950), 2015-06, Vol.194 (11), p.5120-5128

2015

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Cutting Edge: Inherent and Acquired Resistance to Radiation-Induced Apoptosis in B Cells: A Pivotal Role for STAT3

The Journal of immunology (1950), 2006-11, Vol.177 (10), p.6593-6597

2006

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CD19 Function in Early and Late B Cell Development. II. CD19 Facilitates the Pro-B/Pre-B Transition

The Journal of immunology (1950), 2003-12, Vol.171 (11), p.5921-5930

2003

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CD19-dependent Activation of Akt Kinase in B-lymphocytes

The Journal of biological chemistry, 2001-01, Vol.276 (2), p.1474-1478

2001

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Dynamic interaction of PSGL-1 with the T cell receptor regulates the extent of T cell activation

The Journal of immunology (1950), 2019-05, Vol.202 (1_Supplement), p.187-187.36

2019

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CD19 function in central and peripheral B-cell development

Immunologic research, 2005-01, Vol.31 (2), p.119-132

2005

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PSGL-1 deficiency eradicates orthotopic pancreatic ductal adenocarcinoma tumors in combination with anti-PD-1 therapy and enhances T cell anti-tumor immunity

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.172-172.14

2023

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PSGL-1-directed regulation of calcium signaling modulates PD-1 expression following T cell activation

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.80-80.19

2020

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PSGL-1 deficiency re-wires T cell signaling to support development of stem cell like exhausted T cells that control PD-1 blockade resistant melanoma tumor growth

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.172-172.24

2023

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RNF5-deficiency inhibits CD8+ T cell exhaustion in chronic antigen stimulation

The Journal of immunology (1950), 2021-05, Vol.206 (1_Supplement), p.14-14.12

2021

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PSGL-1 regulates the extent of TCR-dependent activation in T cells and prevents their suppression by Tregs

The Journal of immunology (1950), 2018-05, Vol.200 (1_Supplement), p.47-47.25

2018

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Immunometabolism regulation by PSGL-1 signaling in tumor-specific CD8 T cells

The Journal of immunology (1950), 2020-05, Vol.204 (1_Supplement), p.240-240.1

2020

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

Siah2 control of T-regulatory cells limits anti-tumor immunity

Striking a Balance-Cellular and Molecular Drivers of Memory T Cell Development and Responses to Chronic Stimulation

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion

PSGL-1: A New Player in the Immune Checkpoint Landscape

T cell-intrinsic and -extrinsic contributions of the IFNAR/STAT1-axis to thymocyte survival

CD19 Function in Early and Late B Cell Development: I. Maintenance of Follicular and Marginal Zone B Cells Requires CD19-Dependent Survival Signals

IRF7-dependent IFN-β production in response to RANKL promotes medullary thymic epithelial cell development

B-cell survival and development controlled by the coordination of NF-κB family members RelB and cRel

MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8 + T Cell Responses

Activation of IKKα target genes depends on recognition of specific κB binding sites by RelB:p52 dimers

Alternative and Classical NF-κB Signaling Retain Autoreactive B Cells in the Splenic Marginal Zone and Result in Lupus-like Disease

IFN-β Selectively Inhibits IL-2 Production through CREM-Mediated Chromatin Remodeling

Cutting Edge: Inherent and Acquired Resistance to Radiation-Induced Apoptosis in B Cells: A Pivotal Role for STAT3

CD19 Function in Early and Late B Cell Development. II. CD19 Facilitates the Pro-B/Pre-B Transition

CD19-dependent Activation of Akt Kinase in B-lymphocytes

Dynamic interaction of PSGL-1 with the T cell receptor regulates the extent of T cell activation

CD19 function in central and peripheral B-cell development

PSGL-1 deficiency eradicates orthotopic pancreatic ductal adenocarcinoma tumors in combination with anti-PD-1 therapy and enhances T cell anti-tumor immunity

PSGL-1-directed regulation of calcium signaling modulates PD-1 expression following T cell activation

PSGL-1 deficiency re-wires T cell signaling to support development of stem cell like exhausted T cells that control PD-1 blockade resistant melanoma tumor growth

RNF5-deficiency inhibits CD8+ T cell exhaustion in chronic antigen stimulation

PSGL-1 regulates the extent of TCR-dependent activation in T cells and prevents their suppression by Tregs

Immunometabolism regulation by PSGL-1 signaling in tumor-specific CD8 T cells

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