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New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.236-244

2015

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Identification of antiviral antihistamines for COVID-19 repurposing

Biochemical and biophysical research communications, 2021-01, Vol.538, p.173-179

2021

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The Elusive Coreceptors for the SARS-CoV-2 Spike Protein

Viruses, 2022-12, Vol.15 (1), p.67

2022

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Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection

PloS one, 2016-01, Vol.11 (1), p.e0147230-e0147230

2016

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Identification of drug-specific public TCR driving severe cutaneous adverse reactions

Nature communications, 2019-08, Vol.10 (1), p.3569-13, Article 3569

2019

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Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

Proceedings of the National Academy of Sciences - PNAS, 2012-06, Vol.109 (25), p.9959-9964

2012

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Taste Receptors Function as Nutrient Sensors in Pancreatic Islets: A Potential Therapeutic Target for Diabetes

Endocrine, metabolic & immune disorders drug targets, 2023-01, Vol.23 (9), p.1137-1150

2023

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Prediction of Off-Target Effects on Angiotensin-Converting Enzyme 2

Journal of biomolecular screening, 2011-09, Vol.16 (8), p.878-885

2011

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Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population

PloS one, 2023-01, Vol.18 (1), p.e0276700

2023

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Abacavir-reactive memory T cells are present in drug naïve individuals

PloS one, 2015-02, Vol.10 (2), p.e0117160-e0117160

2015

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Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements

International journal of molecular sciences, 2020-12, Vol.22 (1), p.80

2020

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Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics

International journal of molecular sciences, 2023-11, Vol.24 (21), p.15718

2023

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Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

International journal of oncology, 2017-11, Vol.51 (5), p.1370-1382

2017

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Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells

Journal of medicinal chemistry, 2013-02, Vol.56 (3), p.1276-1290

2013

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New approaches for predicting T cell–mediated drug reactions: A role for inducible and potentially preventable autoimmunity

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.252-257

2015

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HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping

Journal of allergy and clinical immunology, 2015-01, Vol.135 (1), p.253-259.e10

2015

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Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

Hypertension (Dallas, Tex. 1979), 2008-05, Vol.51 (5), p.1312-1317

2008

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Discovery of Novel DNA Gyrase Inhibitors by High-Throughput Virtual Screening

Antimicrobial Agents and Chemotherapy, 2007-10, Vol.51 (10), p.3688-3698

2007

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Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

Scientific reports, 2017-08, Vol.7 (1), p.8653-12, Article 8653

2017

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Structural Elements Recognized by Abacavir-Induced T Cells

International journal of molecular sciences, 2017-07, Vol.18 (7), p.1464

2017

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Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy

Journal of allergy and clinical immunology, 2015-08, Vol.136 (2), p.262-271.e2

2015

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Epitope Mapping of Pathogenic Autoantigens on Sjögren's Syndrome-Susceptible Human Leukocyte Antigens Using In Silico Techniques

Journal of clinical medicine, 2022-03, Vol.11 (6), p.1690

2022

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Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

Molecules (Basel, Switzerland), 2021-02, Vol.26 (4), p.983

2021

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Alpha-1 antitrypsin: A novel biomarker and potential therapeutic approach for metabolic diseases

Clinica chimica acta, 2022-09, Vol.534, p.71-76

2022

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The structural basis of HLA-associated drug hypersensitivity syndromes

Immunological reviews, 2012-11, Vol.250 (1), p.158-166

2012

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New genetic findings lead the way to a better understanding of fundamental mechanisms of drug hypersensitivity

Identification of antiviral antihistamines for COVID-19 repurposing

The Elusive Coreceptors for the SARS-CoV-2 Spike Protein

Identification of a Small Molecule Inhibitor of RAD52 by Structure-Based Selection

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire

Taste Receptors Function as Nutrient Sensors in Pancreatic Islets: A Potential Therapeutic Target for Diabetes

Prediction of Off-Target Effects on Angiotensin-Converting Enzyme 2

Ancestral origins are associated with SARS-CoV-2 susceptibility and protection in a Florida patient population

Abacavir-reactive memory T cells are present in drug naïve individuals

Multiple Recombination Events and Strong Purifying Selection at the Origin of SARS-CoV-2 Spike Glycoprotein Increased Correlated Dynamic Movements

Sigma Receptor Ligands Prevent COVID Mortality In Vivo: Implications for Future Therapeutics

Two novel atypical PKC inhibitors; ACPD and DNDA effectively mitigate cell proliferation and epithelial to mesenchymal transition of metastatic melanoma while inducing apoptosis

Potent Elastase Inhibitors from Cyanobacteria: Structural Basis and Mechanisms Mediating Cytoprotective and Anti-Inflammatory Effects in Bronchial Epithelial Cells

New approaches for predicting T cell–mediated drug reactions: A role for inducible and potentially preventable autoimmunity

HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping

Structure-Based Identification of Small-Molecule Angiotensin-Converting Enzyme 2 Activators as Novel Antihypertensive Agents

Discovery of Novel DNA Gyrase Inhibitors by High-Throughput Virtual Screening

Shared peptide binding of HLA Class I and II alleles associate with cutaneous nevirapine hypersensitivity and identify novel risk alleles

Structural Elements Recognized by Abacavir-Induced T Cells

Report from the National Institute of Allergy and Infectious Diseases workshop on drug allergy

Epitope Mapping of Pathogenic Autoantigens on Sjögren's Syndrome-Susceptible Human Leukocyte Antigens Using In Silico Techniques

Sweet-Tasting Ionic Conjugates of Local Anesthetics and Vasoconstrictors

Alpha-1 antitrypsin: A novel biomarker and potential therapeutic approach for metabolic diseases

The structural basis of HLA-associated drug hypersensitivity syndromes

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