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A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer’s mouse model via an HSF1-mediated mechanism

Molecular psychiatry, 2017-07, Vol.22 (7), p.990-1001

2017

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Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region

Molecular psychiatry, 2017-07, Vol.22 (7), p.935-935

2017

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Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling

Cellular and molecular neurobiology, 2003-06, Vol.23 (3), p.305-314

2003

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Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase

The Journal of biological chemistry, 2001-11, Vol.276 (45), p.42063-42069

2001

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The M2-muscarinic receptor inhibits the development of streptozotocin-induced neuropathy in mouse urinary bladder

The Journal of pharmacology and experimental therapeutics, 2010-10, Vol.335 (1), p.239

2010

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Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP

American Journal of Physiology: Cell Physiology, 2001-08, Vol.281 (2), p.C524-C531

2001

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Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s)

The Journal of pharmacology and experimental therapeutics, 2000-08, Vol.294 (2), p.407

2000

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Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder

Naunyn-Schmiedeberg's archives of pharmacology, 2010-05, Vol.381 (5), p.441-454

2010

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Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.11735-11739

2000

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Hypertonic Stress Increases T Cell Interleukin-2 Expression through a Mechanism That Involves ATP Release, P2 Receptor, and p38 MAPK Activation

The Journal of biological chemistry, 2003-02, Vol.278 (7), p.4590-4596

2003

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Caveolar Microdomains of the Sarcolemma: Compartmentation of Signaling Molecules Comes of Age

Circulation research, 1999-05, Vol.84 (9), p.1110-1112

1999

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Selective enhancement of beta-adrenergic receptor signaling by overexpression of adenylyl cyclase type 6: colocalization of receptor and adenylyl cyclase in caveolae of cardiac myocytes

Molecular pharmacology, 2000-05, Vol.57 (5), p.1075-1079

2000

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Biochemical methods for detection and measurement of cyclic AMP and adenylyl cyclase activity

Methods in molecular biology (Clifton, N.J.), 2000, Vol.126, p.363

2000

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SUBTYPES OF THE MUSCARINIC RECEPTOR IN SMOOTH MUSCLE

Life sciences (1973), 1997, Vol.61 (18), p.1729-1740

1997

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The evolving role of lipid rafts and caveolae in G protein‐coupled receptor signaling: implications for molecular pharmacology

British journal of pharmacology, 2004-09, Vol.143 (2), p.235-245

2004

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P2Y receptors of MDCK cells: epithelial cell regulation by extracellular nucleotides

Clinical and experimental pharmacology & physiology, 2001-04, Vol.28 (4), p.351-354

2001

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RGS-PX1, a GAP for Gαs and sorting nexin in vesicular trafficking

Science (American Association for the Advancement of Science), 2001-11, Vol.294 (5548), p.1939-1942

2001

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A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer%apos;s mouse model via an HSF1-mediated mechanism

Molecular psychiatry, 2017-07, Vol.22 (7), p.990

2017

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C64 HAVING A BLAST WITH FIBROBLASTS: Pge2 Up-Regulates Pde4 Enzyme Activity To Induce A Pge2-Selective Desensitization Of Camp Accumulation In Lung Fibroblasts

American journal of respiratory and critical care medicine, 2015-01, Vol.191, p.1

2015

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The M 2 -Muscarinic Receptor Inhibits the Development of Streptozotocin-Induced Neuropathy in Mouse Urinary Bladder

The Journal of pharmacology and experimental therapeutics, 2010-10, Vol.335 (1), p.239-248

2010

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Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor

The Journal of pharmacology and experimental therapeutics, 2013-11, Vol.347 (2), p.276-287

2013

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New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains

Molecular pharmacology, 2002-03, Vol.61 (3), p.473-476

Ostrom, Rennolds S

2002

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cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts

American Journal of Physiology: Cell Physiology, 2004-05, Vol.286 (5), p.C1089-C1099

2004

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Caveolae and Lipid Rafts: G Protein-Coupled Receptor Signaling Microdomains in Cardiac Myocytes

Annals of the New York Academy of Sciences, 2005-06, Vol.1047 (1), p.166-172

2005

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Nitric Oxide Inhibition of Adenylyl Cyclase Type 6 Activity Is Dependent upon Lipid Rafts and Caveolin Signaling Complexes

The Journal of biological chemistry, 2004-05, Vol.279 (19), p.19846-19853

2004

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A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer’s mouse model via an HSF1-mediated mechanism

Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region

Forskolin as a tool for examining adenylyl cyclase expression, regulation, and G protein signaling

Receptor Number and Caveolar Co-localization Determine Receptor Coupling Efficiency to Adenylyl Cyclase

The M2-muscarinic receptor inhibits the development of streptozotocin-induced neuropathy in mouse urinary bladder

Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP

Stoichiometry and compartmentation in G protein-coupled receptor signaling: implications for therapeutic interventions involving G(s)

Impaired M3 and enhanced M2 muscarinic receptor contractile function in a streptozotocin model of mouse diabetic urinary bladder

Cellular Release of and Response to ATP as Key Determinants of the Set-Point of Signal Transduction Pathways

Hypertonic Stress Increases T Cell Interleukin-2 Expression through a Mechanism That Involves ATP Release, P2 Receptor, and p38 MAPK Activation

Caveolar Microdomains of the Sarcolemma: Compartmentation of Signaling Molecules Comes of Age

Selective enhancement of beta-adrenergic receptor signaling by overexpression of adenylyl cyclase type 6: colocalization of receptor and adenylyl cyclase in caveolae of cardiac myocytes

Biochemical methods for detection and measurement of cyclic AMP and adenylyl cyclase activity

SUBTYPES OF THE MUSCARINIC RECEPTOR IN SMOOTH MUSCLE

The evolving role of lipid rafts and caveolae in G protein‐coupled receptor signaling: implications for molecular pharmacology

P2Y receptors of MDCK cells: epithelial cell regulation by extracellular nucleotides

RGS-PX1, a GAP for Gαs and sorting nexin in vesicular trafficking

A CNS-permeable Hsp90 inhibitor rescues synaptic dysfunction and memory loss in APP-overexpressing Alzheimer%apos;s mouse model via an HSF1-mediated mechanism

C64 HAVING A BLAST WITH FIBROBLASTS: Pge2 Up-Regulates Pde4 Enzyme Activity To Induce A Pge2-Selective Desensitization Of Camp Accumulation In Lung Fibroblasts

The M 2 -Muscarinic Receptor Inhibits the Development of Streptozotocin-Induced Neuropathy in Mouse Urinary Bladder

Development of a high-throughput screening paradigm for the discovery of small-molecule modulators of adenylyl cyclase: identification of an adenylyl cyclase 2 inhibitor

New determinants of receptor-effector coupling: trafficking and compartmentation in membrane microdomains

cAMP-elevating agents and adenylyl cyclase overexpression promote an antifibrotic phenotype in pulmonary fibroblasts

Caveolae and Lipid Rafts: G Protein-Coupled Receptor Signaling Microdomains in Cardiac Myocytes

Nitric Oxide Inhibition of Adenylyl Cyclase Type 6 Activity Is Dependent upon Lipid Rafts and Caveolin Signaling Complexes

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