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The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and Pharmacokinetics

Journal of pharmaceutical sciences, 2008-09, Vol.97 (9), p.3942-3956

2008

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Mechanism of alkene epoxidation by iron, chromium, and manganese higher valent oxo-metalloporphyrins

Accounts of chemical research, 1992-07, Vol.25 (7), p.314-320

1992

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Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 5. Epoxidation of alkenes catalyzed by a sterically hindered (meso-tetrakis(2,6-dibromophenyl)porphinato)iron(III) chloride

Journal of the American Chemical Society, 1989-08, Vol.111 (17), p.6511-6517

1989

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A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents

Pharmaceutical research, 2009-10, Vol.26 (10), p.2303-2313

2009

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Design and characterization of a surfactant-enriched tablet formulation for oral delivery of a poorly water-soluble immunosuppressive agent

International journal of pharmaceutics, 1999-05, Vol.182 (2), p.173-186

1999

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Is a linear relationship between the free energies of activation and one-electron oxidation potential evidence for one-electron transfer being rate determining? Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 4. Epoxidation of a series of alkenes by oxo(meso-tetrakis(2,6-dibromophenyl)porphinato)chromium(V)

Journal of the American Chemical Society, 1989-06, Vol.111 (13), p.4960-4966

1989

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Kinetics and Mechanism of the Hydrolytic Degradation of Indinavir: Intramolecular Catalysis

Journal of pharmaceutical sciences, 2008-09, Vol.97 (9), p.3810-3819

2008

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Structure sensitivity of the Marcus .lambda. for hydride transfer between NAD+ analogs

Journal of the American Chemical Society, 1988, Vol.110 (2), p.524-530

1988

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L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Journal of medicinal chemistry, 1994-10, Vol.37 (21), p.3443-3451

1994

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Isotope effects on hydride transfer between NAD+ analogs

Journal of the American Chemical Society, 1983-12, Vol.105 (26), p.7629-7631

1983

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Assessing aggregation of peptide conjugate of doxorubicin using quasi-elastic light scattering and 600 MHz NMR

International journal of pharmaceutics, 2004-03, Vol.271 (1), p.181-187

2004

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Marcus theory of hydride transfer from an anionic reduced deazaflavin to NAD+ analogs

Journal of the American Chemical Society, 1988-06, Vol.110 (12), p.3989-3993

1988

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Phenomenological manifestations of large-curvature tunneling in hydride-transfer reactions

Journal of physical chemistry (1952), 1986-07, Vol.90 (16), p.3766-3774

1986

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Solid-state nuclear magnetic resonance determination of the physical form of BHA on common pharmaceutical excipients

Pharmaceutical research, 2004-01, Vol.21 (1), p.185-188

2004

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Kinetics and mechanism of oxygen transfer in the reaction of p-cyano-N,N-dimethylaniline N-oxide with metalloporphyrin salts. 5. The influence of imidazole ligation of (meso-tetrakis(2,6-dimethylphenyl)porphinato)manganese(III) chloride on the rates of oxygen transfer from N-oxide to metalloporphyrin salt and the efficiency of oxidations by the intermediate higher valent manganese-oxo species

Journal of the American Chemical Society, 1987-05, Vol.109 (11), p.3428-3436

1987

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Design of an IV Formulation of an Unstable Prodrug Candidate for Prostate Cancer Treatment: Solution Chemistry of N-(glutaryl-hyp-ala-ser-cyclohexylglycyl-gln-ser-leu)-doxorubicin

Drug development and industrial pharmacy, 2006-01, Vol.32 (3), p.327-334

2006

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Hydride transfer and oxyanion addition equilibria of NAD+ analogs

Journal of organic chemistry, 1985-11, Vol.50 (22), p.4206-4211

1985

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Identification of oxidative degradates of the thrombin inhibitor, 3-(2-phenethylamino)-6-methyl-1-(2-amino-6-methyl-5-methylenecarboxamidomethylpyridinyl)pyrazinone, using liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 1999-07, Vol.20 (3), p.471-485

1999

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Development of Subcutaneous and Intramuscular Formulations of Calcium Alendronate Salts

Drug development and industrial pharmacy, 1995, Vol.21 (10), p.1157-1169

1995

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Regiospecific intestinal absorption of the HIV protease inhibitor L-735,524 in beagle dogs

Pharmaceutical research, 1995-06, Vol.12 (6), p.884-888

1995

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HYDRIDE TRANSFER BETWEEN NAD('+) ANALOGUES (MARCUS THEORY, ISOTOPE EFFECTS)

OSTOVIC, DRAZEN

1985

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A new hydroxyethylamine class of HIV-1 protease inhibitors with high antiviral potency and oral bioavailability

Bioorganic & medicinal chemistry letters, 1994-10, Vol.4 (19), p.2273-2278

1994

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Transition state geometry in epoxidation by iron-oxo porphyrin at the compound I oxidation level. Epoxidation of alkenes catalyzed by a sterically hindered meso-tetrakis(2,6-dibromophenyl)porphinato iron(III) chloride

Journal of the American Chemical Society, 1988-09, Vol.110 (20), p.6906-6908

1988

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A rapid bioassay for the determination of non-nucleoside HIV-1 reverse transcriptase inhibitor plasma levels

Life sciences (1973), 1993, Vol.52 (3), p.243-249

1993

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Transition-state geometry in epoxidation by Iron-oxo porphyrin at the compound I oxidation level. Epoxidation of alkenes catalyzed by a sterically hindered (meso-tetrakis(2,6-dibromophenyl)porphinato)iron(III) chloride

Journal of the American Chemical Society, 1988-09, Vol.110 (20), p.6906-6908

1988

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The Co‐Crystal Approach to Improve the Exposure of a Water‐Insoluble Compound: AMG 517 Sorbic Acid Co‐Crystal Characterization and Pharmacokinetics

Mechanism of alkene epoxidation by iron, chromium, and manganese higher valent oxo-metalloporphyrins

Intermediates in the epoxidation of alkenes by cytochrome P-450 models. 5. Epoxidation of alkenes catalyzed by a sterically hindered (meso-tetrakis(2,6-dibromophenyl)porphinato)iron(III) chloride

A Quantitative Kinetic Study of Polysorbate Autoxidation: The Role of Unsaturated Fatty Acid Ester Substituents

Design and characterization of a surfactant-enriched tablet formulation for oral delivery of a poorly water-soluble immunosuppressive agent

Kinetics and Mechanism of the Hydrolytic Degradation of Indinavir: Intramolecular Catalysis

Structure sensitivity of the Marcus .lambda. for hydride transfer between NAD+ analogs

L-735,524: The Design of a Potent and Orally Bioavailable HIV Protease Inhibitor

Isotope effects on hydride transfer between NAD+ analogs

Assessing aggregation of peptide conjugate of doxorubicin using quasi-elastic light scattering and 600 MHz NMR

Marcus theory of hydride transfer from an anionic reduced deazaflavin to NAD+ analogs

Phenomenological manifestations of large-curvature tunneling in hydride-transfer reactions

Solid-state nuclear magnetic resonance determination of the physical form of BHA on common pharmaceutical excipients

Design of an IV Formulation of an Unstable Prodrug Candidate for Prostate Cancer Treatment: Solution Chemistry of N-(glutaryl-hyp-ala-ser-cyclohexylglycyl-gln-ser-leu)-doxorubicin

Hydride transfer and oxyanion addition equilibria of NAD+ analogs

Identification of oxidative degradates of the thrombin inhibitor, 3-(2-phenethylamino)-6-methyl-1-(2-amino-6-methyl-5-methylenecarboxamidomethylpyridinyl)pyrazinone, using liquid chromatography/mass spectrometry and liquid chromatography/tandem mass spectrometry

Development of Subcutaneous and Intramuscular Formulations of Calcium Alendronate Salts

Regiospecific intestinal absorption of the HIV protease inhibitor L-735,524 in beagle dogs

HYDRIDE TRANSFER BETWEEN NAD('+) ANALOGUES (MARCUS THEORY, ISOTOPE EFFECTS)

A new hydroxyethylamine class of HIV-1 protease inhibitors with high antiviral potency and oral bioavailability

Transition state geometry in epoxidation by iron-oxo porphyrin at the compound I oxidation level. Epoxidation of alkenes catalyzed by a sterically hindered meso-tetrakis(2,6-dibromophenyl)porphinato iron(III) chloride

A rapid bioassay for the determination of non-nucleoside HIV-1 reverse transcriptase inhibitor plasma levels

Transition-state geometry in epoxidation by Iron-oxo porphyrin at the compound I oxidation level. Epoxidation of alkenes catalyzed by a sterically hindered (meso-tetrakis(2,6-dibromophenyl)porphinato)iron(III) chloride

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