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Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans

Toxicological sciences, 2020-01, Vol.173 (1), p.86-99

2020

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Toward a Comprehensive Molecular Design Framework for Reduced Hazard

Chemical reviews, 2010-10, Vol.110 (10), p.5845-5882

2010

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Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse

Toxicological sciences, 2019-04, Vol.168 (2), p.572-596

2019

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Perspectives on interpretation of Rivera-González et al., (2021)

Chemosphere (Oxford), 2022-02, Vol.288 (Pt 2), p.132599-132599, Article 132599

2022

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Evaluation of the utility of the lifetime mouse bioassay in the identification of cancer hazards for humans

Food and chemical toxicology, 2013-10, Vol.60, p.550-562

2013

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Assess flame retardants with care

Science (American Association for the Advancement of Science), 2019-09, Vol.365 (6457), p.992-993

2019

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Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk

Critical reviews in toxicology, 2009-07, Vol.39 (6), p.501-511

2009

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Evaluation of potential toxicity of smoke from controlled burns of furnished rooms - effect of flame retardancy

Journal of Toxicology and Environmental Health, Part A, 2022-10, Vol.85 (19), p.783-797

2022

Volltextzugriff (PDF)

Comment on “Concentrations of Brominated Flame Retardants in Indoor Air and Dust from Ireland Reveal Elevated Exposure to Decabromodiphenyl Ethane”

Environmental science & technology, 2020-09, Vol.54 (18), p.11631-11633

2020

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An Evaluation of the Human Relevance of the Liver Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action

Toxicological sciences, 2020-05, Vol.175 (1), p.50-63

2020

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Subchronic toxicology of tetrabromobisphenol A in rats

Human & experimental toxicology, 2016-11, Vol.35 (11), p.1214-1226

2016

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Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations

Xenobiotica, 2019-04, Vol.49 (4), p.388-396

2019

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Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance

Toxicology (Amsterdam), 2020-06, Vol.439, p.152465, Article 152465

2020

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Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes

Xenobiotica, 2019-05, Vol.49 (5), p.521-527

2019

Volltextzugriff (PDF)

Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation

Toxicological sciences, 2019-06, Vol.169 (2), p.365-379

2019

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An Evaluation of the Human Relevance of the Lung Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action

Toxicological sciences, 2017-06, Vol.157 (2), p.465-486

2017

Volltextzugriff (PDF)

Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes

Xenobiotica, 2020-12, Vol.50 (12), p.1434-1442

2020

Volltextzugriff (PDF)

Mode of action analysis for pesticide-induced rodent liver tumours involving activation of the constitutive androstane receptor: relevance to human cancer risk

Pest management science, 2015-06, Vol.71 (6), p.829-834

2015

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Safety assessment of the use of Bacillus-based cleaning products

Food and chemical toxicology, 2018-06, Vol.116 (Pt A), p.42-52

2018

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Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

Drug metabolism and disposition, 2017-05, Vol.45 (5), p.468-475

2017

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Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids

Toxicological sciences, 2020-08, Vol.176 (2), p.460-469

2020

Volltextzugriff (PDF)

Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes

Toxicology (Amsterdam), 2008-01, Vol.243 (1), p.84-95

2008

Volltextzugriff (PDF)

Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats

Toxicology (Amsterdam), 2020-10, Vol.443, p.152563, Article 152563

2020

Volltextzugriff (PDF)

A mode of action for induction of liver tumors by Pyrethrins in the rat

Toxicology and applied pharmacology, 2007-01, Vol.218 (2), p.186-195

2007

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Polyester monomers lack ability to bind and activate both androgenic and estrogenic receptors as determined by In Vitro and In Silico methods

Food and chemical toxicology, 2015-01, Vol.75, p.128-138

2015

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Development and Application of a Life-Stage Physiologically Based Pharmacokinetic (PBPK) Model to the Assessment of Internal Dose of Pyrethroids in Humans

Toward a Comprehensive Molecular Design Framework for Reduced Hazard

Involvement of Peroxisome Proliferator-Activated Receptor-Alpha in Liver Tumor Production by Permethrin in the Female Mouse

Perspectives on interpretation of Rivera-González et al., (2021)

Evaluation of the utility of the lifetime mouse bioassay in the identification of cancer hazards for humans

Assess flame retardants with care

Mode-of-action analysis for induction of rat liver tumors by pyrethrins: relevance to human cancer risk

Evaluation of potential toxicity of smoke from controlled burns of furnished rooms - effect of flame retardancy

Comment on “Concentrations of Brominated Flame Retardants in Indoor Air and Dust from Ireland Reveal Elevated Exposure to Decabromodiphenyl Ethane”

An Evaluation of the Human Relevance of the Liver Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action

Subchronic toxicology of tetrabromobisphenol A in rats

Metabolism of deltamethrin and cis- and trans-permethrin by rat and human liver microsomes, liver cytosol and plasma preparations

Piperonyl butoxide: Mode of action analysis for mouse liver tumour formation and human relevance

Metabolism of deltamethrin and cis- and trans-permethrin by human expressed cytochrome P450 and carboxylesterase enzymes

Evaluation of Age-Related Pyrethroid Pharmacokinetic Differences in Rats: Physiologically-Based Pharmacokinetic Model Development Using In Vitro Data and In Vitro to In Vivo Extrapolation

An Evaluation of the Human Relevance of the Lung Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action

Metabolism of bifenthrin, β-cyfluthrin, λ-cyhalothrin, cyphenothrin and esfenvalerate by rat and human cytochrome P450 and carboxylesterase enzymes

Mode of action analysis for pesticide-induced rodent liver tumours involving activation of the constitutive androstane receptor: relevance to human cancer risk

Safety assessment of the use of Bacillus-based cleaning products

Determination of Human Hepatic CYP2C8 and CYP1A2 Age-Dependent Expression to Support Human Health Risk Assessment for Early Ages

Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids

Effect of Pyrethrins on cytochrome P450 forms in cultured rat and human hepatocytes

Differential lymphatic versus portal vein uptake of the synthetic pyrethroids deltamethrin and cis-permethrin in rats

A mode of action for induction of liver tumors by Pyrethrins in the rat

Polyester monomers lack ability to bind and activate both androgenic and estrogenic receptors as determined by In Vitro and In Silico methods

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