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Understanding MCL1: from cellular function and regulation to pharmacological inhibition

The FEBS journal, 2022-10, Vol.289 (20), p.6209-6234

2022

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Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

Cell death & disease, 2021-12, Vol.12 (12), p.1155-1155, Article 1155

2021

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The past, present, and future of breast cancer models for nanomedicine development

Advanced drug delivery reviews, 2021-06, Vol.173, p.306-330

2021

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Real‐Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Angewandte Chemie International Edition, 2020-08, Vol.59 (35), p.15152-15156

International ed. in English, 2020

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Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

Cell death & disease, 2018-03, Vol.9 (3), p.365-12, Article 365

2018

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Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation

Analytical biochemistry, 2022-02, Vol.638, p.114510-114510, Article 114510

2022

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Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice

Pharmacological research, 2022-09, Vol.183, p.106356-106356, Article 106356

2022

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The chemistry of senescence

Nature reviews. Chemistry, 2019-07, Vol.3 (7), p.426-441

2019

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Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release

ACS applied materials & interfaces, 2018-08, Vol.10 (33), p.27644-27656

2018

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Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic

Journal of controlled release, 2020-07, Vol.323, p.624-634

2020

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MUC1 Aptamer‐Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple‐Negative Breast Cancer

Chemistry : a European journal, 2020-12, Vol.26 (69), p.16318-16327

2020

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Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

International journal of nanomedicine, 2022-01, Vol.17, p.409-422

2022

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Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

Journal of controlled release, 2021-09, Vol.337, p.14-26

2021

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A renal clearable fluorogenic probe for in vivo β-galactosidase activity detection during aging and senolysis

Nature communications, 2024-01, Vol.15 (1), p.775-16, Article 775

2024

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Janus Gold Nanostars–Mesoporous Silica Nanoparticles for NIR‐Light‐Triggered Drug Delivery

Chemistry : a European journal, 2019-06, Vol.25 (36), p.8471-8478

2019

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Identification of NLRP3PYD Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

International journal of molecular sciences, 2022-01, Vol.23 (3), p.1651

2022

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Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (45), p.27980-27988

2020

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Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

ACS applied materials & interfaces, 2018-08, Vol.10 (31), p.26494-26500

2018

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Targeted Delivery of The Pan-Inflammasome Inhibitor MM01 as An Alternative Approach to Acute Lung Injury Therapy

Advanced healthcare materials, 2023-11, Vol.12 (28), p.e2301577-e2301577

2023

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Phenotyping of cancer-associated somatic mutations in the BCL2 transmembrane domain

Oncogenesis (New York, NY), 2024-04, Vol.13 (1), p.14-14, Article 14

2024

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Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

Chemical communications (Cambridge, England), 2014-01, Vol.50 (24), p.3184-3186

2014

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Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes

Proceedings of the National Academy of Sciences - PNAS, 2017-01, Vol.114 (2), p.310-315

2017

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In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models

Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.11866-11871

2011

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BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Molecular & cellular oncology, 2021-01, Vol.8 (1), p.1859918-1859918

2021

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Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety

Chemistry : a European journal, 2015-09, Vol.21 (40), p.14122-14128

2015

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Understanding MCL1: from cellular function and regulation to pharmacological inhibition

Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases

The past, present, and future of breast cancer models for nanomedicine development

Real‐Time In Vivo Detection of Cellular Senescence through the Controlled Release of the NIR Fluorescent Dye Nile Blue

Cytochrome c speeds up caspase cascade activation by blocking 14-3-3ε-dependent Apaf-1 inhibition

Split-luciferase complementary assay of NLRP3 PYD-PYD interaction indicates inflammasome formation during inflammation

Pharmacological senolysis reduces doxorubicin-induced cardiotoxicity and improves cardiac function in mice

The chemistry of senescence

Gold Nanostars Coated with Mesoporous Silica Are Effective and Nontoxic Photothermal Agents Capable of Gate Keeping and Laser-Induced Drug Release

Preclinical antitumor efficacy of senescence-inducing chemotherapy combined with a nanoSenolytic

MUC1 Aptamer‐Capped Mesoporous Silica Nanoparticles for Navitoclax Resistance Overcoming in Triple‐Negative Breast Cancer

Horseradish Peroxidase-Functionalized Gold Nanoconjugates for Breast Cancer Treatment Based on Enzyme Prodrug Therapy

Targeted-lung delivery of dexamethasone using gated mesoporous silica nanoparticles. A new therapeutic approach for acute lung injury treatment

A renal clearable fluorogenic probe for in vivo β-galactosidase activity detection during aging and senolysis

Janus Gold Nanostars–Mesoporous Silica Nanoparticles for NIR‐Light‐Triggered Drug Delivery

Identification of NLRP3PYD Homo-Oligomerization Inhibitors with Anti-Inflammatory Activity

Mcl-1 and Bok transmembrane domains: Unexpected players in the modulation of apoptosis

Hybrid Mesoporous Nanocarriers Act by Processing Logic Tasks: Toward the Design of Nanobots Capable of Reading Information from the Environment

Targeted Delivery of The Pan-Inflammasome Inhibitor MM01 as An Alternative Approach to Acute Lung Injury Therapy

Phenotyping of cancer-associated somatic mutations in the BCL2 transmembrane domain

Temperature-controlled release by changes in the secondary structure of peptides anchored onto mesoporous silica supports

Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes

In vivo discovery of a peptide that prevents CUG-RNA hairpin formation and reverses RNA toxicity in myotonic dystrophy models

BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Efficient Synthesis of Conformationally Restricted Apoptosis Inhibitors Bearing a Triazole Moiety

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