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Exploiting the unusual effects of fluorine in methodology

Chemical communications (Cambridge, England), 2017-06, Vol.53 (53), p.7168-7181

2017

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Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of gem-Difluoroalkenes

Journal of organic chemistry, 2020-08, Vol.85 (16), p.10451-10465

2020

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Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition

Chemical science (Cambridge), 2015-01, Vol.6 (2), p.1212-1218

2015

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Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α-Difluoroalkylthioethers

Journal of organic chemistry, 2021-02, Vol.86 (3), p.2297-2311

2021

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Base Catalysis Enables Access to α,α-Difluoroalkylthioethers

Organic letters, 2017-04, Vol.19 (7), p.1570-1573

2017

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Organocatalytic strategy for hydrophenolation of gem-difluoroalkenes

Tetrahedron, 2019-08, Vol.75 (32), p.4325-4336

2019

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Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Angewandte Chemie (International ed.), 2015-02, Vol.54 (8), p.2361-2365

2015

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Correction to “Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α-Difluoroalkylthioethers”

Journal of organic chemistry, 2021-03, Vol.86 (5), p.4374-4374

2021

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Cu(II)-Catalyzed Unsymmetrical Dioxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-phenoxyketones

Journal of organic chemistry, 2022-08, Vol.87 (16), p.10710-10725

2022

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Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.14394-14413

2024

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Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069

Journal of medicinal chemistry, 2022-11, Vol.65 (21), p.14843-14863

2022

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Discovery of a potent M5 antagonist with improved clearance profile. Part 2: Pyrrolidine amide-based antagonists

Bioorganic & medicinal chemistry letters, 2022-12, Vol.78, p.129021-129021, Article 129021

2022

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Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

Journal of medicinal chemistry, 2023-01, Vol.66 (1), p.1082-1082

2023

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Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists

Bioorganic & medicinal chemistry, 2023-01, Vol.78, p.117130-117130, Article 117130

2023

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BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale

Organic process research & development, 2019-08, Vol.23 (8), p.1695-1702

2019

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Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Angewandte Chemie, 2015-02, Vol.127 (8), p.2391-2395

2015

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Cu(II)-Catalyzed Unsymmetrical Di-oxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-Phenoxyketones

Journal of organic chemistry, 2022-08, Vol.87 (16), p.10710-10725

2022

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Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M 5 Muscarinic Acetylcholine Receptor

Journal of medicinal chemistry, 2024-08, Vol.67 (16), p.14394-14413

2024

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Discovery of a potent M5 antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonists

Bioorganic & medicinal chemistry letters, 2022-11, Vol.76, p.128988-128988, Article 128988

2022

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Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access [alpha],[alpha]-Difluoroketones

Angewandte Chemie International Edition, 2015-02, Vol.54 (8), p.2361

International ed. in English, 2015

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Fluorination Enables a Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Angewandte Chemie International Edition, 2015-01, Vol.54 (8), p.2361-2365

2015

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Discovery of a potent M 5 antagonist with improved clearance profile. Part 2: Pyrrolidine amide-based antagonists

Bioorganic & medicinal chemistry letters, 2022-12, Vol.78, p.129021

2022

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Discovery of a potent M 5 antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonists

Bioorganic & medicinal chemistry letters, 2022-11, Vol.76, p.128988

2022

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Exploiting the unusual effects of fluorine in methodology

Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of gem-Difluoroalkenes

Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition

Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α-Difluoroalkylthioethers

Base Catalysis Enables Access to α,α-Difluoroalkylthioethers

Organocatalytic strategy for hydrophenolation of gem-difluoroalkenes

Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Correction to “Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α-Difluoroalkylthioethers”

Cu(II)-Catalyzed Unsymmetrical Dioxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-phenoxyketones

Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M5 Muscarinic Acetylcholine Receptor

Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069

Discovery of a potent M5 antagonist with improved clearance profile. Part 2: Pyrrolidine amide-based antagonists

Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists

BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale

Development of VU6019650 : A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M 5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder

Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Cu(II)-Catalyzed Unsymmetrical Di-oxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-Phenoxyketones

Development of VU6036864: A Triazolopyridine-Based High-Quality Antagonist Tool Compound of the M 5 Muscarinic Acetylcholine Receptor

Discovery of a potent M5 antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonists

Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access [alpha],[alpha]-Difluoroketones

Fluorination Enables a Ligand-Controlled Regiodivergent Palladium-Catalyzed Decarboxylative Allylation Reaction to Access α,α-Difluoroketones

Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder

Discovery of a potent M 5 antagonist with improved clearance profile. Part 2: Pyrrolidine amide-based antagonists

Discovery of a potent M 5 antagonist with improved clearance profile. Part 1: Piperidine amide-based antagonists

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