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ATP-Binding Cassette Cholesterol Transporters and Cardiovascular Disease

Circulation research, 2006-11, Vol.99 (10), p.1031-1043

2006

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The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor

The Journal of biological chemistry, 2009-11, Vol.284 (47), p.32336-32343

2009

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ABCG1 Redistributes Cell Cholesterol to Domains Removable by High Density Lipoprotein but Not by Lipid-depleted Apolipoproteins

The Journal of biological chemistry, 2005-08, Vol.280 (34), p.30150-30157

2005

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Myeloperoxidase: An Oxidative Pathway for Generating Dysfunctional High-Density Lipoprotein

Chemical research in toxicology, 2010-03, Vol.23 (3), p.447-454

2010

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Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

The Journal of clinical investigation, 2007-03, Vol.117 (3), p.746-756

2007

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Apolipoprotein A-I attenuates palmitate-mediated NF-κB activation by reducing Toll-like receptor-4 recruitment into lipid rafts

PloS one, 2012-03, Vol.7 (3), p.e33917-e33917

2012

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Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C δ pathway

Journal of lipid research, 2007-05, Vol.48 (5), p.1062-1068

2007

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Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux

Journal of lipid research, 2009-02, Vol.50 (2), p.275-284

2009

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ABCA1. The gatekeeper for eliminating excess tissue cholesterol

Journal of lipid research, 2001-08, Vol.42 (8), p.1173-1179

2001

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The Myeloperoxidase Product Hypochlorous Acid Oxidizes HDL in the Human Artery Wall and Impairs ABCA1-Dependent Cholesterol Transport

Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (35), p.13032-13037

2004

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Unsaturated Fatty Acids Inhibit Cholesterol Efflux from Macrophages by Increasing Degradation of ATP-binding Cassette Transporter A1

The Journal of biological chemistry, 2002-02, Vol.277 (7), p.5692-5697

2002

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Myeloperoxidase Impairs ABCA1-dependent Cholesterol Efflux through Methionine Oxidation and Site-specific Tyrosine Chlorination of Apolipoprotein A-I

The Journal of biological chemistry, 2006-04, Vol.281 (14), p.9001-9004

2006

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ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

Journal of lipid research, 2003-07, Vol.44 (7), p.1373-1380

2003

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Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport

The Journal of biological chemistry, 2005-02, Vol.280 (7), p.5983-5993

2005

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ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation

Journal of lipid research, 2009-02, Vol.50 (2), p.285-292

2009

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ATP-binding cassette transporter A1 and cholesterol trafficking

Current opinion in lipidology, 2002-08, Vol.13 (4), p.373-381

Oram, John F

2002

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Unsaturated Fatty Acids Phosphorylate and Destabilize ABCA1 through a Phospholipase D2 Pathway

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.35896-35903

2005

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Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species

The Journal of biological chemistry, 2004-10, Vol.279 (41), p.42977-42983

2004

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A Macrophage Sterol-Responsive Network Linked to Atherogenesis

Cell metabolism, 2010-02, Vol.11 (2), p.125-135

2010

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LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1

Journal of lipid research, 2004-05, Vol.45 (5), p.972-980

2004

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Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells

The Journal of biological chemistry, 2003-12, Vol.278 (52), p.52379-52385

2003

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ATP-Binding Cassette Transporter A1: A Cell Cholesterol Exporter That Protects Against Cardiovascular Disease

Physiological reviews, 2005-10, Vol.85 (4), p.1343-1372

2005

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The cell cholesterol exporter ABCA1 as a protector from cardiovascular disease and diabetes

Biochimica et biophysica acta, 2009-07, Vol.1791 (7), p.563-572

2009

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Janus Kinase 2 Modulates the Apolipoprotein Interactions with ABCA1 Required for Removing Cellular Cholesterol

The Journal of biological chemistry, 2004-02, Vol.279 (9), p.7622-7628

2004

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An Amphipathic Helical Region of the N-terminal Barrel of Phospholipid Transfer Protein Is Critical for ABCA1-dependent Cholesterol Efflux

The Journal of biological chemistry, 2008-04, Vol.283 (17), p.11541-11549

2008

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ATP-Binding Cassette Cholesterol Transporters and Cardiovascular Disease

The Macrophage Cholesterol Exporter ABCA1 Functions as an Anti-inflammatory Receptor

ABCG1 Redistributes Cell Cholesterol to Domains Removable by High Density Lipoprotein but Not by Lipid-depleted Apolipoproteins

Myeloperoxidase: An Oxidative Pathway for Generating Dysfunctional High-Density Lipoprotein

Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL

Apolipoprotein A-I attenuates palmitate-mediated NF-κB activation by reducing Toll-like receptor-4 recruitment into lipid rafts

Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C δ pathway

Effects of acceptor composition and mechanism of ABCG1-mediated cellular free cholesterol efflux

ABCA1. The gatekeeper for eliminating excess tissue cholesterol

The Myeloperoxidase Product Hypochlorous Acid Oxidizes HDL in the Human Artery Wall and Impairs ABCA1-Dependent Cholesterol Transport

Unsaturated Fatty Acids Inhibit Cholesterol Efflux from Macrophages by Increasing Degradation of ATP-binding Cassette Transporter A1

Myeloperoxidase Impairs ABCA1-dependent Cholesterol Efflux through Methionine Oxidation and Site-specific Tyrosine Chlorination of Apolipoprotein A-I

ABCA1 redistributes membrane cholesterol independent of apolipoprotein interactions

Tyrosine 192 in Apolipoprotein A-I Is the Major Site of Nitration and Chlorination by Myeloperoxidase, but Only Chlorination Markedly Impairs ABCA1-dependent Cholesterol Transport

ABCA1 mutants reveal an interdependency between lipid export function, apoA-I binding activity, and Janus kinase 2 activation

ATP-binding cassette transporter A1 and cholesterol trafficking

Unsaturated Fatty Acids Phosphorylate and Destabilize ABCA1 through a Phospholipase D2 Pathway

Human Atherosclerotic Intima and Blood of Patients with Established Coronary Artery Disease Contain High Density Lipoprotein Damaged by Reactive Nitrogen Species

A Macrophage Sterol-Responsive Network Linked to Atherogenesis

LXR-mediated activation of macrophage stearoyl-CoA desaturase generates unsaturated fatty acids that destabilize ABCA1

Phospholipid Transfer Protein Interacts with and Stabilizes ATP-binding Cassette Transporter A1 and Enhances Cholesterol Efflux from Cells

ATP-Binding Cassette Transporter A1: A Cell Cholesterol Exporter That Protects Against Cardiovascular Disease

The cell cholesterol exporter ABCA1 as a protector from cardiovascular disease and diabetes

Janus Kinase 2 Modulates the Apolipoprotein Interactions with ABCA1 Required for Removing Cellular Cholesterol

An Amphipathic Helical Region of the N-terminal Barrel of Phospholipid Transfer Protein Is Critical for ABCA1-dependent Cholesterol Efflux

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