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Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.71-81

2000

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Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation

ACS chemical biology, 2017-10, Vol.12 (10), p.2619-2630

2017

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Selective inhibition of human type 1 11β-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

FEBS letters, 1998-12, Vol.441 (1), p.25-28

1998

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Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

PloS one, 2016-02, Vol.11 (2), p.e0148762-e0148762

2016

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Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases

Molecular and cellular endocrinology, 2001-01, Vol.171 (1), p.99-101

2001

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Heterogeneity of 11β-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11β-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.63-69

2000

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Lack of quinone reductase activity suggests that amyloid-β peptide/ERAB induced lipid peroxidation is not directly related to production of reactive oxygen species by redoxcycling

Toxicology (Amsterdam), 2000-04, Vol.144 (1), p.163-168

2000

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The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins

Journal of structural and functional genomics, 2007-09, Vol.8 (2-3), p.107-119

2007

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Forms and functions of human SDR enzymes

Chemico-biological interactions, 2001-01, Vol.130 (1-3), p.699-705

2001

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Active Site Directed Mutagenesis of 3β/17β-Hydroxysteroid Dehydrogenase Establishes Differential Effects on Short-Chain Dehydrogenase/Reductase Reactions

Biochemistry (Easton), 1997-01, Vol.36 (1), p.34-40

1997

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Carbonyl reduction of an anti-insect agent imidazole analogue of metyrapone in soil bacteria, invertebrate and vertebrate species

Chemico-biological interactions, 1998-07, Vol.114 (3), p.211-224

1998

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Type 1 11β-Hydroxysteroid Dehydrogenase Mediates Glucocorticoid Activation and Insulin Release in Pancreatic Islets

The Journal of biological chemistry, 2000-11, Vol.275 (45), p.34841-34844

2000

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Structure of Bacterial 3β/17β-Hydroxysteroid Dehydrogenase at 1.2 Å Resolution: A Model for Multiple Steroid Recognition

Biochemistry (Easton), 2002-12, Vol.41 (50), p.14659-14668

2002

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Binding of amyloid β-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer’s disease

FEBS letters, 1999-05, Vol.451 (3), p.238-242

1999

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The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

European journal of biochemistry, 1997-10, Vol.249 (2), p.365-369

1997

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Antibiotic resistance and enhanced insecticide catabolism as consequences of steroid induction in the Gram-negative bacterium Comamonas testosteroni

The Journal of steroid biochemistry and molecular biology, 1996-05, Vol.58 (2), p.217-223

1996

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The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

European journal of biochemistry, 1997-10, Vol.249 (2), p.355-360

1997

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In vitro methods in toxicology

Toxicology (Amsterdam), 1993-11, Vol.84 (1-3), p.233-234

Oppermann, Udo C.T.

1993

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Characterization of a 3α‐Hydroxysteroid Dehydrogenase/Carbonyl Reductase from the Gram‐Negative Bacterium Comamonas testosteroni

European journal of biochemistry, 1996-11, Vol.241 (3), p.744-749

1996

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Human type 10 17β-hydroxysteroid dehydrogenase: molecular modelling and substrate docking

Journal of molecular graphics & modelling, 2001-01, Vol.19 (6), p.514-520

2001

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Structure-function relationships of SDR hydroxysteroid dehydrogenases

Advances in experimental medicine and biology, 1997, Vol.414, p.403

1997

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Isolation and structure of repressor‐like proteins from the archaeon Sulfolobus solfataricus

FEBS letters, 1998-08, Vol.432 (3), p.141-144

1998

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An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli: structural and enzymatic relationships to the eukaryotic protein forms

European journal of biochemistry, 1999-07, Vol.263 (2), p.305-311

1999

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Cloning and Primary Structure of Murine 11β‐Hydroxysteroid Dehydrogenase/Microsomal Carbonyl Reductase

European journal of biochemistry, 1995-01, Vol.227 (1‐2), p.202-208

1995

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Molecular and structural aspects of xenobiotic carbonyl metabolizing enzymes. Role of reductases and dehydrogenases in xenobiotic phase I reactions

Selective Targeting of Bromodomains of the Bromodomain-PHD Fingers Family Impairs Osteoclast Differentiation

Selective inhibition of human type 1 11β-hydroxysteroid dehydrogenase by synthetic steroids and xenobiotics

Structures of Two Melanoma-Associated Antigens Suggest Allosteric Regulation of Effector Binding

GGPS1 Mutations Cause Muscular Dystrophy/Hearing Loss/Ovarian Insufficiency Syndrome

Subcellular targeting analysis of SDR-type hydroxysteroid dehydrogenases

Heterogeneity of 11β-hydroxysteroid dehydrogenase type 1/microsomal carbonyl reductase (11β-HSD/CR) in guinea pig tissues. Purification of the liver form suggests modification in the cosubstrate binding site

Lack of quinone reductase activity suggests that amyloid-β peptide/ERAB induced lipid peroxidation is not directly related to production of reactive oxygen species by redoxcycling

The scientific impact of the Structural Genomics Consortium: a protein family and ligand-centered approach to medically-relevant human proteins

Forms and functions of human SDR enzymes

Active Site Directed Mutagenesis of 3β/17β-Hydroxysteroid Dehydrogenase Establishes Differential Effects on Short-Chain Dehydrogenase/Reductase Reactions

Carbonyl reduction of an anti-insect agent imidazole analogue of metyrapone in soil bacteria, invertebrate and vertebrate species

Type 1 11β-Hydroxysteroid Dehydrogenase Mediates Glucocorticoid Activation and Insulin Release in Pancreatic Islets

Structure of Bacterial 3β/17β-Hydroxysteroid Dehydrogenase at 1.2 Å Resolution: A Model for Multiple Steroid Recognition

Binding of amyloid β-peptide to mitochondrial hydroxyacyl-CoA dehydrogenase (ERAB): regulation of an SDR enzyme activity with implications for apoptosis in Alzheimer’s disease

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

Antibiotic resistance and enhanced insecticide catabolism as consequences of steroid induction in the Gram-negative bacterium Comamonas testosteroni

The 11β‐Hydroxysteroid Dehydrogenase System, A Determinant of Glucocorticoid and Mineralocorticoid Action

In vitro methods in toxicology

Characterization of a 3α‐Hydroxysteroid Dehydrogenase/Carbonyl Reductase from the Gram‐Negative Bacterium Comamonas testosteroni

Human type 10 17β-hydroxysteroid dehydrogenase: molecular modelling and substrate docking

Structure-function relationships of SDR hydroxysteroid dehydrogenases

Isolation and structure of repressor‐like proteins from the archaeon Sulfolobus solfataricus

An ethanol-inducible MDR ethanol dehydrogenase/acetaldehyde reductase in Escherichia coli: structural and enzymatic relationships to the eukaryotic protein forms

Cloning and Primary Structure of Murine 11β‐Hydroxysteroid Dehydrogenase/Microsomal Carbonyl Reductase

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