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Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments

PLoS computational biology, 2016-12, Vol.12 (12), p.e1005253

2016

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Impaired dihydrotestosterone catabolism in human prostate cancer : Critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling

Cancer research (Chicago, Ill.), 2007-02, Vol.67 (3), p.1361-1369

2007

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Role of the Liver in Interorgan Homeostasis of Glutathione and Cyst(e)ine

Seminars in liver disease, 1998, Vol.18 (4), p.313-329

1998

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Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells

American journal of physiology: Gastrointestinal and liver physiology, 2003-12, Vol.285 (6), p.G1335-G1344

2003

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Effect of Transgenic Extrahepatic Expression of Betaine-Homocysteine Methyltransferase on Alcohol or Homocysteine-Induced Fatty Liver

Alcoholism, clinical and experimental research, 2008-06, Vol.32 (6), p.1049-1058

2008

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Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol‐treated rats: Effect of membrane physical properties and S‐adenosyl‐L‐methionine

Hepatology (Baltimore, Md.), 1997-09, Vol.26 (3), p.699-708

1997

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3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism

The journal of clinical endocrinology and metabolism, 2008-04, Vol.93 (4), p.1298-1303

2008

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3α-Hydroxysteroid Dehydrogenase Type III Deficiency: A Novel Mechanism for Hirsutism

The journal of clinical endocrinology and metabolism, 2008-04, Vol.93 (4), p.1298-1303

2008

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Amiodarone-digoxin interaction: Clinical significance, time course of development, potential pharmacokinetic mechanisms and therapeutic implications

Journal of the American College of Cardiology, 1984-07, Vol.4 (1), p.111-116

1984

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Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells

American journal of physiology: Gastrointestinal and liver physiology, 2003-12, Vol.48 (6), p.G1335-G1344

2003

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Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats

The Journal of biological chemistry, 1992-01, Vol.267 (3), p.1667-1673

1992

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Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats : tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress

The Journal of clinical investigation, 1991-02, Vol.87 (2), p.397-405

1991

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Role of two recently cloned rat liver GSH transporters in the ubiquitous transport of GSH in mammalian cells

The Journal of clinical investigation, 1996-03, Vol.97 (6), p.1488-1496

1996

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Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat

The Journal of clinical investigation, 1990-06, Vol.85 (6), p.2009-2013

1990

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Hormonal regulation of glutathione efflux

The Journal of biological chemistry, 1990-09, Vol.265 (27), p.16088-16095

1990

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Radiation inactivation studies of hepatic sinusoidal reduced glutathione transport system

Biochimica et biophysica acta, 2000-04, Vol.1464 (2), p.207-218

2000

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Developmental changes in plasma thiol-disulfide turnover in rats: A multicompartmental approach

American journal of physiology. Regulatory, integrative and comparative physiology, 1994-08, Vol.36 (2), p.R415

1994

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Plasma Membrane and Mitochondrial Transport of Hepatic Reduced Glutathione

Seminars in liver disease, 1996-05, Vol.16 (2), p.147-158

1996

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Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles

The Journal of biological chemistry, 1993-05, Vol.268 (15), p.10836-10841

1993

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Effect of chronic ethanol feeding on rat hepatocytic glutathione. Compartmentation, efflux, and response to incubation with ethanol

The Journal of clinical investigation, 1987-07, Vol.80 (1), p.57-62

1987

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Novel properties of hepatic canalicular reduced glutathione transport revealed by radiation inactivation

American journal of physiology: Gastrointestinal and liver physiology, 1998-05, Vol.274 (5), p.G923-G930

1998

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Novel properties of hepatic canalicular reduced glutathione transport revealed by radiation inactivation

American journal of physiology: Gastrointestinal and liver physiology, 1998-05, Vol.37 (5), p.G923-G930

1998

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Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin: kinetics, sidedness, and molecular forms

The Journal of clinical investigation, 1988-08, Vol.82 (2), p.608-616

1988

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Evidence that interference with binding to hepatic cytosol binders can inhibit bile acid excretion in rats

Hepatology (Baltimore, Md.), 1996, Vol.23 (6), p.1642-1649

1996

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Changes in plasma glutathione concentrations, turnover, and disposal in developing rats

American journal of physiology. Regulatory, integrative and comparative physiology, 1994-03, Vol.35 (3), p.R979-R988

1994

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Competing Mechanistic Hypotheses of Acetaminophen-Induced Hepatotoxicity Challenged by Virtual Experiments

Impaired dihydrotestosterone catabolism in human prostate cancer : Critical role of AKR1C2 as a pre-receptor regulator of androgen receptor signaling

Role of the Liver in Interorgan Homeostasis of Glutathione and Cyst(e)ine

Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells

Effect of Transgenic Extrahepatic Expression of Betaine-Homocysteine Methyltransferase on Alcohol or Homocysteine-Induced Fatty Liver

Transport of reduced glutathione in hepatic mitochondria and mitoplasts from ethanol‐treated rats: Effect of membrane physical properties and S‐adenosyl‐L‐methionine

3alpha-Hydroxysteroid dehydrogenase type III deficiency: a novel mechanism for hirsutism

3α-Hydroxysteroid Dehydrogenase Type III Deficiency: A Novel Mechanism for Hirsutism

Amiodarone-digoxin interaction: Clinical significance, time course of development, potential pharmacokinetic mechanisms and therapeutic implications

Chelerythrine stimulates GSH transport by rat Mrp2 (Abcc2) expressed in canine kidney cells

Canalicular transport of reduced glutathione in normal and mutant Eisai hyperbilirubinemic rats

Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats : tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stress

Role of two recently cloned rat liver GSH transporters in the ubiquitous transport of GSH in mammalian cells

Evidence for carrier-mediated transport of glutathione across the blood-brain barrier in the rat

Hormonal regulation of glutathione efflux

Radiation inactivation studies of hepatic sinusoidal reduced glutathione transport system

Developmental changes in plasma thiol-disulfide turnover in rats: A multicompartmental approach

Plasma Membrane and Mitochondrial Transport of Hepatic Reduced Glutathione

Selective induction by phenobarbital of the electrogenic transport of glutathione and organic anions in rat liver canalicular membrane vesicles

Effect of chronic ethanol feeding on rat hepatocytic glutathione. Compartmentation, efflux, and response to incubation with ethanol

Novel properties of hepatic canalicular reduced glutathione transport revealed by radiation inactivation

Novel properties of hepatic canalicular reduced glutathione transport revealed by radiation inactivation

Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin: kinetics, sidedness, and molecular forms

Evidence that interference with binding to hepatic cytosol binders can inhibit bile acid excretion in rats

Changes in plasma glutathione concentrations, turnover, and disposal in developing rats

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