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Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

Pharmacology & therapeutics (Oxford), 1997, Vol.73 (2), p.147-171

1997

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Absorption, metabolism, and excretion of [14C]imidafenacin, a new compound for treatment of overactive bladder, after oral administration to healthy male subjects

Drug metabolism and disposition, 2007-09, Vol.35 (9), p.1624-1633

2007

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Development and validation of bioanalytical methods for Imidafenacin (KRP-197/ONO-8025) and its metabolites in human plasma by liquid chromatography–tandem mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007-06, Vol.853 (1-2), p.70-79

2007

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Development and validation of bioanalytical methods for imidafenacin (KRP-197/ONO-8025) and its metabolites in human urine by using liquid chromatography-tandem mass spectrometry

Biomedical chromatography, 2007-09, Vol.21 (9), p.940-948

2007

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Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics

The Journal of pharmacology and experimental therapeutics, 1997-10, Vol.283 (1), p.293

1997

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PREDICTION OF IN VIVO DRUG DISPOSITION FROM IN VITRO DATA BASED ON PHYSIOLOGICAL PHARMACOKINETICS

Biopharmaceutics & drug disposition, 1996-05, Vol.17 (4), p.273-310

1996

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Quantitative brain microdialysis study on the mechanism of quinolones distribution in the central nervous system

Drug metabolism and disposition, 1997-07, Vol.25 (7), p.784

1997

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Distributed model analysis of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine distribution in brain tissue and cerebrospinal fluid

The Journal of pharmacology and experimental therapeutics, 1997-09, Vol.282 (3), p.1509

1997

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臨床薬物動態学薬物治療の適正化のために, 第2版, 緒方宏泰編著, 増原慶壮,松本宜明,木島慎一,高橋晴美著, 丸善, B5, 224頁, 5,040円

ファルマシア, 2008/01/01, Vol.44(1), pp.66

大家, 毅

2008

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Comparative distribution of quinolone antibiotics in cerebrospinal fluid and brain in rats and dogs

The Journal of pharmacology and experimental therapeutics, 1996-08, Vol.278 (2), p.590

1996

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Characterization of the transport properties of a quinolone antibiotic, fleroxacin, in rat choroid plexus

Pharmaceutical research, 1996-04, Vol.13 (4), p.523-527

1996

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Kinetics of quinolone antibiotics in rats : Efflux from cerebrospinal fluid to the circulation

Pharmaceutical research, 1996-07, Vol.13 (7), p.1065-1068

1996

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Disposition of Amorolfine Hydrochloride in Rats. Percutaneous Absorption, Distribution and Excretion after Single Dermal Application

Yakubutsu dōtai = Xenobiotic metabolism and disposition, 1994, Vol.9 (4), p.499-509

1994

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High-performance liquid chromatographic determination of 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid and its metabolites in laboratory animals

Journal of chromatography, 1986, Vol.381 (1), p.137-148

1986

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Kinetic analysis of the distribution of quinolone antibiotics in the central nervous system: Role of active efflux transport from the brain

Yakubutsu dōtai = Xenobiotic metabolism and disposition, 1996-09, Vol.11 (supplement), p.5112-5113

1996

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Kinetic analysis of the transport of the quinolone antibiotics across the blood-brain barrier and blood-CSF barrier

Yakubutsu dōtai = Xenobiotic metabolism and disposition, 1993-10, Vol.8 (supplement), p.755-758

1993

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A physical model of tsunami inundation and wave pressures for an idealized coastal industrial site

Coastal engineering (Amsterdam), 2021-10, Vol.169, p.103970, Article 103970

2021

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Observational study of the effects of dabigatran on gastrointestinal symptoms in patients with non-valvular atrial fibrillation

Journal of arrhythmia, 2014-12, Vol.30 (6), p.478-484

2014

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Prediction of in vivo drug metabolism in the human liver from in vitro metabolism data

Absorption, metabolism, and excretion of [14C]imidafenacin, a new compound for treatment of overactive bladder, after oral administration to healthy male subjects

Development and validation of bioanalytical methods for Imidafenacin (KRP-197/ONO-8025) and its metabolites in human plasma by liquid chromatography–tandem mass spectrometry

Development and validation of bioanalytical methods for imidafenacin (KRP-197/ONO-8025) and its metabolites in human urine by using liquid chromatography-tandem mass spectrometry

Kinetic evidence for active efflux transport across the blood-brain barrier of quinolone antibiotics

PREDICTION OF IN VIVO DRUG DISPOSITION FROM IN VITRO DATA BASED ON PHYSIOLOGICAL PHARMACOKINETICS

Quantitative brain microdialysis study on the mechanism of quinolones distribution in the central nervous system

Distributed model analysis of 3'-azido-3'-deoxythymidine and 2',3'-dideoxyinosine distribution in brain tissue and cerebrospinal fluid

臨床薬物動態学薬物治療の適正化のために, 第2版, 緒方宏泰編著, 増原慶壮,松本宜明,木島慎一,高橋晴美著, 丸善, B5, 224頁, 5,040円

Comparative distribution of quinolone antibiotics in cerebrospinal fluid and brain in rats and dogs

Characterization of the transport properties of a quinolone antibiotic, fleroxacin, in rat choroid plexus

Kinetics of quinolone antibiotics in rats : Efflux from cerebrospinal fluid to the circulation

Disposition of Amorolfine Hydrochloride in Rats. Percutaneous Absorption, Distribution and Excretion after Single Dermal Application

High-performance liquid chromatographic determination of 6,8-difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid and its metabolites in laboratory animals

Kinetic analysis of the distribution of quinolone antibiotics in the central nervous system: Role of active efflux transport from the brain

Kinetic analysis of the transport of the quinolone antibiotics across the blood-brain barrier and blood-CSF barrier

A physical model of tsunami inundation and wave pressures for an idealized coastal industrial site

Observational study of the effects of dabigatran on gastrointestinal symptoms in patients with non-valvular atrial fibrillation

Validation of tsunami numerical simulation models for an idealized coastal industrial site

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