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Trojan horses and guided missiles: targeted therapies in the war on arthritis

Nature reviews. Rheumatology, 2015-06, Vol.11 (6), p.328-337

2015

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Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

Nature medicine, 2017-12, Vol.23 (12), p.1416-1423

2017

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Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis

Drug discovery today, 2016-01, Vol.21 (1), p.172-179

2016

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Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

Journal of virology, 2021-09, Vol.95 (19), p.e0068521-e0068521

2021

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Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction

Scientific reports, 2021-11, Vol.11 (1), p.21902-21902, Article 21902

2021

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Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation

Arthritis & rheumatology (Hoboken, N.J.), 2015-10, Vol.67 (10), p.2661-2672

2015

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Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

Frontiers in immunology, 2021-02, Vol.12, p.640070-640070

2021

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Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

mAbs, 2021-01, Vol.13 (1), p.1864084-1864084

2021

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Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

Nature communications, 2024-02, Vol.15 (1), p.1583-1583, Article 1583

2024

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A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

Scientific reports, 2020-11, Vol.10 (1), p.19168-19168, Article 19168

2020

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Knotted Fusion Proteins Reveal Unexpected Possibilities in Protein Folding

Molecular cell, 2008-06, Vol.30 (5), p.642-648

2008

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Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

Journal for immunotherapy of cancer, 2023-06, Vol.11 (6), p.e006699

2023

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Optimised Method for the Production and Titration of Lentiviral Vectors Pseudotyped with the SARS-CoV-2 Spike

Bio-protocol, 2021-08, Vol.11 (16), p.e4194-e4194

2021

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Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

Nature medicine, 2019-09, Vol.25 (9), p.1408-1414

2019

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An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma

Blood, 2018-02, Vol.131 (7), p.746-758

2018

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A Rapamycin-Activated Caspase 9-Based Suicide Gene

Molecular therapy, 2018-05, Vol.26 (5), p.1266-1276

2018

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Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Molecular therapy, 2023-07, Vol.31 (7), p.2089-2104

2023

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Anti-CD21 Chimeric Antigen Receptor (CAR)-T Cells for T Cell Acute Lymphoblastic Leukaemia (T-ALL)

Blood, 2021-11, Vol.138 (Supplement 1), p.902-902

2021

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Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction

ACS chemical biology, 2024-02, Vol.19 (2), p.308-324

2024

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A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

Antiviral research, 2021-10, Vol.194, p.105147-105147, Article 105147

2021

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Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Molecular therapy, 2024-02, Vol.32 (2), p.556-558

2024

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Abstract 2183: Targeting TRBC1 and 2 for the treatment of T cell lymphomas

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.2183-2183

2020

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Abstract 1070: AUTO7: Anti-PSMA humanized CAR T-cell with improved persistence and resistance to tumor microenvironment for metastatic castration resistant prostate cancer (mCRPC)

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.1070-1070

2020

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AIRE-Deficient Patients Harbor Unique High-Affinity Disease-Ameliorating Autoantibodies

Trojan horses and guided missiles: targeted therapies in the war on arthritis

Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia: a phase 1 trial

Going with the flow: harnessing the power of the vasculature for targeted therapy in rheumatoid arthritis

Characterization of a Novel ACE2-Based Therapeutic with Enhanced Rather than Reduced Activity against SARS-CoV-2 Variants

Tunable control of CAR T cell activity through tetracycline mediated disruption of protein–protein interaction

Rational Design of Antirheumatic Prodrugs Specific for Sites of Inflammation

Novel Bispecific Antibody for Synovial-Specific Target Delivery of Anti-TNF Therapy in Rheumatoid Arthritis

Combining phage display with SMRTbell next-generation sequencing for the rapid discovery of functional scFv fragments

Structure-guided engineering of immunotherapies targeting TRBC1 and TRBC2 in T cell malignancies

A primer set for the rapid isolation of scFv fragments against cell surface antigens from immunised rats

Knotted Fusion Proteins Reveal Unexpected Possibilities in Protein Folding

Limited efficacy of APRIL CAR in patients with multiple myeloma indicate challenges in the use of natural ligands for CAR T-cell therapy

Optimised Method for the Production and Titration of Lentiviral Vectors Pseudotyped with the SARS-CoV-2 Spike

Enhanced CAR T cell expansion and prolonged persistence in pediatric patients with ALL treated with a low-affinity CD19 CAR

An APRIL-based chimeric antigen receptor for dual targeting of BCMA and TACI in multiple myeloma

A Rapamycin-Activated Caspase 9-Based Suicide Gene

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Anti-CD21 Chimeric Antigen Receptor (CAR)-T Cells for T Cell Acute Lymphoblastic Leukaemia (T-ALL)

Designer Small-Molecule Control System Based on Minocycline-Induced Disruption of Protein–Protein Interaction

A tetrameric ACE2 protein broadly neutralizes SARS-CoV-2 spike variants of concern with elevated potency

Dual targeting of CD19 and CD22 against B-ALL using a novel high-sensitivity aCD22 CAR

Abstract 2183: Targeting TRBC1 and 2 for the treatment of T cell lymphomas

Abstract 1070: AUTO7: Anti-PSMA humanized CAR T-cell with improved persistence and resistance to tumor microenvironment for metastatic castration resistant prostate cancer (mCRPC)

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