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Receptor-isoform-selective insulin analogues give tissue-preferential effects

Biochemical journal, 2011-12, Vol.440 (3), p.301-308

2011

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802-P: Beneficial Effects of a Functionally Selective Insulin on Vascular Function and Liver Triglycerides

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome

Diabetes (New York, N.Y.), 2018-05, Vol.67 (5), p.946-959

2018

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Treatment of diabetic rats with insulin or a synthetic insulin receptor agonist peptide leads to divergent metabolic responses

Diabetes (New York, N.Y.), 2015-03, Vol.64 (3), p.1057-1066

2015

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AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle

American journal of physiology: endocrinology and metabolism, 2002-11, Vol.283 (5), p.E965-E970

2002

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Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: Overexpression of protein kinase Cε in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.584-592

2001

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Identification and Synthesis of a Novel Selective Partial PPARδ Agonist with Full Efficacy on Lipid Metabolism In Vitro and In Vivo

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1495-1503

2007

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Design of potent PPARα agonists

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3198-3202

2007

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Insulin Signaling Is Inhibited by Micromolar Concentrations of H2O2

The Journal of biological chemistry, 1999-08, Vol.274 (35), p.25078-25084

1999

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Cellular Mechanism of Nutritionally Induced Insulin Resistance in Psammomys Obesus

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.584-592

2001

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A-769662 activates AMPK β 1 -containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

American Journal of Physiology: Cell Physiology, 2009-10, Vol.297 (4), p.C1041-C1052

2009

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A-769662 activates AMPK {beta}1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

American Journal of Physiology: Cell Physiology, 2009-10, Vol.297 (4), p.C1041

2009

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A-769662 activates AMPK [beta]^sub 1^-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

American Journal of Physiology: Cell Physiology, 2009-10, Vol.297 (4), p.C1041

2009

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A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

American Journal of Physiology: Cell Physiology, 2009, Vol.66 (4)

2009

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AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle

American journal of physiology: endocrinology and metabolism, 2002-11, Vol.46 (5), p.E965-E970

2002

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Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo

Journal of medicinal chemistry, 2007-04, Vol.50 (7), p.1495-1503

2007

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Design of potent PPARalpha agonists

Bioorganic & medicinal chemistry letters, 2007-06, Vol.17 (11), p.3198-3202

2007

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A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

American Journal of Physiology: Cell Physiology, 2009-10, Vol.297 (4), p.C1041-C1052

2009

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Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: Overexpression of protein kinase C(epsilon) in skeletal muscle precedes the onset of

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.584

2001

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Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of Protein Kinase C[[epsilon] in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

Diabetes (New York, N.Y.), 2001-03, Vol.50 (3), p.584

2001

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Achilles Tendon Tissue Turnover Before and Immediately After an Acute Rupture

The American journal of sports medicine, 2023-07, Vol.51 (9), p.2396-2403

2023

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Effects of Postdischarge High-Protein Oral Nutritional Supplements and Resistance Training in Malnourished Surgical Patients: A Pilot Randomized Controlled Trial

Nutrients, 2022-06, Vol.14 (13), p.2599

2022

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Free fatty acid-induced PP2A hyperactivity selectively impairs hepatic insulin action on glucose metabolism

PloS one, 2011-11, Vol.6 (11), p.e27424-e27424

2011

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Correlates of Pancreatic Enzyme Replacement Therapy Intake in Adults with Cystic Fibrosis: Results of a Cross-Sectional Study

Nutrients, 2022-03, Vol.14 (7), p.1330

2022

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Receptor-isoform-selective insulin analogues give tissue-preferential effects

802-P: Beneficial Effects of a Functionally Selective Insulin on Vascular Function and Liver Triglycerides

A Novel Strategy to Prevent Advanced Atherosclerosis and Lower Blood Glucose in a Mouse Model of Metabolic Syndrome

Preclinical exploration of combined glucagon inhibition and liver-preferential insulin for treatment of diabetes using in vitro assays and rat and mouse models

Treatment of diabetic rats with insulin or a synthetic insulin receptor agonist peptide leads to divergent metabolic responses

AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: Overexpression of protein kinase Cε in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

Identification and Synthesis of a Novel Selective Partial PPARδ Agonist with Full Efficacy on Lipid Metabolism In Vitro and In Vivo

Design of potent PPARα agonists

Insulin Signaling Is Inhibited by Micromolar Concentrations of H2O2

Cellular Mechanism of Nutritionally Induced Insulin Resistance in Psammomys Obesus

A-769662 activates AMPK β 1 -containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

A-769662 activates AMPK {beta}1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

A-769662 activates AMPK [beta]^sub 1^-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

A-769662 activates AMPK β1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

AMP kinase activation ameliorates insulin resistance induced by free fatty acids in rat skeletal muscle

Identification and synthesis of a novel selective partial PPARdelta agonist with full efficacy on lipid metabolism in vitro and in vivo

Design of potent PPARalpha agonists

A-769662 activates AMPK beta1-containing complexes but induces glucose uptake through a PI3-kinase-dependent pathway in mouse skeletal muscle

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: Overexpression of protein kinase C(epsilon) in skeletal muscle precedes the onset of

Cellular mechanism of nutritionally induced insulin resistance in Psammomys obesus: overexpression of Protein Kinase C[[epsilon] in skeletal muscle precedes the onset of hyperinsulinemia and hyperglycemia

Achilles Tendon Tissue Turnover Before and Immediately After an Acute Rupture

Effects of Postdischarge High-Protein Oral Nutritional Supplements and Resistance Training in Malnourished Surgical Patients: A Pilot Randomized Controlled Trial

Free fatty acid-induced PP2A hyperactivity selectively impairs hepatic insulin action on glucose metabolism

Correlates of Pancreatic Enzyme Replacement Therapy Intake in Adults with Cystic Fibrosis: Results of a Cross-Sectional Study

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