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Screening of Biomarkers in Rat Urine Using LC/Electrospray Ionization-MS and Two-Way Data Analysis

Analytical chemistry (Washington), 2003-09, Vol.75 (18), p.4784-4792

2003

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Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data

Rapid communications in mass spectrometry, 2004-01, Vol.18 (9), p.944-954

2004

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Metabolic fingerprinting of rat urine by LC/MS. Part 2. Data pretreatment methods for handling of complex data

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-12, Vol.828 (1-2), p.14-20

2005

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Improved identification of host cell proteins in a protein biopharmaceutical by LC–MS/MS using the ProteoMiner™ Enrichment Kit

Journal of pharmaceutical and biomedical analysis, 2020-06, Vol.185, p.113256-113256, Article 113256

2020

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Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction

Rapid communications in mass spectrometry, 2005-01, Vol.19 (12), p.1637-1643

2005

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Determination of Dissociation Constants for Protein−Ligand Complexes by Electrospray Ionization Mass Spectrometry

Analytical chemistry (Washington), 2004-08, Vol.76 (15), p.4325-4331

2004

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Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry

Journal of mass spectrometry., 2004-09, Vol.39 (9), p.1059-1067

2004

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A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2010-09, Vol.878 (26), p.2427-2432

2010

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Robust LC–MS/MS methods for analysis of heparan sulfate levels in CSF and brain for application in studies of MPS IIIA

Bioanalysis, 2019-08, Vol.11 (15), p.1389-1403

2019

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Metabolic fingerprinting of rat urine by LC/MS. Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005-12, Vol.828 (1-2), p.9-13

2005

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Digestion of Enolase and Carbonic Anhydrase as Model Proteins for Therapeutic Proteins in Blood Plasma with Immobilized Thermolysin and Quantification of Some of the Peptides by LC/LC–MS/MS

Chromatographia, 2014, Vol.77 (1-2), p.59-74

2014

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On-line microdialysis for enhanced resolution and sensitivity during electrospray mass spectrometry of non-covalent complexes and competitive binding studies

Rapid communications in mass spectrometry, 2002-01, Vol.16 (21), p.2054-2059

2002

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Development of a two-dimensional liquid chromatography system for isolation of drug metabolites

Journal of pharmaceutical and biomedical analysis, 2010-02, Vol.51 (3), p.649-657

2010

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Bioanalytical Method for Quantification of Thioredoxins in Bacillus anthracis by Digestion with Immobilized Pepsin and LC–MS/MS and On-line LC/LC–MS/MS

Chromatographia, 2016, Vol.79 (7-8), p.383-393

2016

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Introduction to early in vitro identification of metabolites of new chemical entities in drug discovery and development

Pharmacological reports, 2006-05, Vol.58 (3), p.341

2006

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Determination of corticosteroids in tissue samples by liquid chromatography–tandem mass spectrometry

Journal of pharmaceutical and biomedical analysis, 2005-02, Vol.37 (2), p.341-350

2005

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Metabolism of 2-substituted quinolines with antileishmanial activity studied in vitro with liver microsomes, hepatocytes and recombinantly expressed enzymes analyzed by LC/MS

Toxicology (Amsterdam), 2007-06, Vol.235 (1), p.27-38

2007

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Sonic spray ionization interface for liquid chromatography–mass spectrometry

Analytica chimica acta, 2002-09, Vol.468 (2), p.263-274

2002

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Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP

Journal of biomolecular screening, 2003-06, Vol.8 (3), p.247-256

2003

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1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans

Drug metabolism and disposition, 1998-11, Vol.26 (11), p.1096

1998

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Detection of anionic polymers by postcolumn ligand exchange with fluorescent cerous ions via a cation-exchange membrane

Analytical chemistry (Washington), 1991-12, Vol.63 (24), p.2888-2891

1991

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Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes

Journal of pharmaceutical and biomedical analysis, 2004-03, Vol.34 (5), p.1079-1090

2004

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Determination of water-soluble vitamins in blood and plasma by coupled-column liquid chromatography

Journal of Chromatography A, 1990-05, Vol.506, p.471-479

1990

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Characterization of the cytochrome P450 enzymes and enzyme kinetic parameters for metabolism of BVT.2938 using different in vitro systems

Journal of pharmaceutical and biomedical analysis, 2006-03, Vol.40 (5), p.1121-1130

2006

Volltextzugriff (PDF)

Metabolic fingerprinting of rat urine by LC/MS

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Vol.828 (1), p.14-20

2005

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Screening of Biomarkers in Rat Urine Using LC/Electrospray Ionization-MS and Two-Way Data Analysis

Multivariate approaches for efficient detection of potential metabolites from liquid chromatography/mass spectrometry data

Metabolic fingerprinting of rat urine by LC/MS. Part 2. Data pretreatment methods for handling of complex data

Improved identification of host cell proteins in a protein biopharmaceutical by LC–MS/MS using the ProteoMiner™ Enrichment Kit

Electrospray ionization mass spectrometry as a tool for determination of drug binding sites to human serum albumin by noncovalent interaction

Determination of Dissociation Constants for Protein−Ligand Complexes by Electrospray Ionization Mass Spectrometry

Influence of droplet size, capillary-cone distance and selected instrumental parameters for the analysis of noncovalent protein-ligand complexes by nano-electrospray ionization mass spectrometry

A novel assay of cellular stearoyl-CoA desaturase activity of primary rat hepatocytes by HPLC

Robust LC–MS/MS methods for analysis of heparan sulfate levels in CSF and brain for application in studies of MPS IIIA

Metabolic fingerprinting of rat urine by LC/MS. Part 1. Analysis by hydrophilic interaction liquid chromatography-electrospray ionization mass spectrometry

Digestion of Enolase and Carbonic Anhydrase as Model Proteins for Therapeutic Proteins in Blood Plasma with Immobilized Thermolysin and Quantification of Some of the Peptides by LC/LC–MS/MS

On-line microdialysis for enhanced resolution and sensitivity during electrospray mass spectrometry of non-covalent complexes and competitive binding studies

Development of a two-dimensional liquid chromatography system for isolation of drug metabolites

Bioanalytical Method for Quantification of Thioredoxins in Bacillus anthracis by Digestion with Immobilized Pepsin and LC–MS/MS and On-line LC/LC–MS/MS

Introduction to early in vitro identification of metabolites of new chemical entities in drug discovery and development

Determination of corticosteroids in tissue samples by liquid chromatography–tandem mass spectrometry

Metabolism of 2-substituted quinolines with antileishmanial activity studied in vitro with liver microsomes, hepatocytes and recombinantly expressed enzymes analyzed by LC/MS

Sonic spray ionization interface for liquid chromatography–mass spectrometry

Automated nano-electrospray mass spectrometry for protein-ligand screening by noncovalent interaction applied to human H-FABP and A-FABP

1- and 3-hydroxylations, in addition to 4-hydroxylation, of debrisoquine are catalyzed by cytochrome P450 2D6 in humans

Detection of anionic polymers by postcolumn ligand exchange with fluorescent cerous ions via a cation-exchange membrane

Identification of BVT.2938 metabolites by LC/MS and LC/MS/MS after in vitro incubations with liver microsomes and hepatocytes

Determination of water-soluble vitamins in blood and plasma by coupled-column liquid chromatography

Characterization of the cytochrome P450 enzymes and enzyme kinetic parameters for metabolism of BVT.2938 using different in vitro systems

Metabolic fingerprinting of rat urine by LC/MS

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