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Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (51), p.21631-21636

2009

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A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly

Proceedings of the National Academy of Sciences - PNAS, 1997-07, Vol.94 (14), p.7464-7468

1997

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Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution

Protein engineering, 2003-02, Vol.16 (2), p.135-145

2003

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The α/β hydrolase fold

Protein engineering, 1992-04, Vol.5 (3), p.197-211

1992

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Of barn owls and bankers: a lush variety of α/β hydrolases

Structure, 1999-06, Vol.7 (6), p.R141-R146

1999

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Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

Nature (London), 1985-01, Vol.313 (6005), p.762-766

1985

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The structure of an enzyme–product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism

Biochimica et biophysica acta, 2005-08, Vol.1752 (1), p.56-64

2005

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Growth of Escherichia coli Coexpressing Phosphotriesterase and Glycerophosphodiester Phosphodiesterase, Using Paraoxon as the Sole Phosphorus Source

Applied and Environmental Microbiology, 2004-01, Vol.70 (1), p.404-412

2004

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Crystal Structure of the N-terminal Domain of the TyrR Transcription Factor Responsible for Gene Regulation of Aromatic Amino Acid Biosynthesis and Transport in Escherichia coli K12

Journal of molecular biology, 2007-03, Vol.367 (1), p.102-112

2007

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Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF)

Acta crystallographica. Section D, Biological crystallography., 2000-11, Vol.56 (11), p.1376-1384

2000

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Structure of the Complete Extracellular Domain of the Common β Subunit of the Human GM-CSF, IL-3, and IL-5 Receptors Reveals a Novel Dimer Configuration

Cell, 2001-01, Vol.104 (2), p.291-300

2001

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Hydrolysis of the 5‘-p-Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III

Biochemistry (Easton), 2002-04, Vol.41 (16), p.5266-5275

2002

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Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction

Structure (London), 1999-04, Vol.7 (4), p.461-475

1999

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A novel functional epitope formed by domains 1 and 4 of the human common beta-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5

The Journal of biological chemistry, 2003-03, Vol.278 (12), p.10572-10577

2003

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In Crystallo Capture of a Michaelis Complex and Product-binding Modes of a Bacterial Phosphotriesterase

Journal of molecular biology, 2008-02, Vol.375 (5), p.1189-1196

2008

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The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transduction

The EMBO journal, 1997-09, Vol.16 (18), p.5562-5571

1997

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The Escherichia coli Signal Transducers PII (GlnB) and GlnK form Heterotrimers in vivo: Fine Tuning the Nitrogen Signal Cascade

Proceedings of the National Academy of Sciences - PNAS, 2000-04, Vol.97 (8), p.3942-3947

2000

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The Structure and Function of a Novel Glycerophosphodiesterase from Enterobacter aerogenes

Journal of molecular biology, 2007-04, Vol.367 (4), p.1047-1062

2007

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The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains

Journal of molecular biology, 1998-03, Vol.276 (5), p.955-966

1998

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A theoretical study of substrate-induced activation of dienelactone hydrolase

Protein engineering, 1995-02, Vol.8 (2), p.135-142

1995

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Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase

Nature (London), 1985-02, Vol.313 (6005), p.818-819

1985

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An improved resolution structure of the human β common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope

Acta crystallographica. Section F, Structural biology and crystallization communications, 2006-06, Vol.62 (6), p.509-513

2006

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Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH

Journal of molecular biology, 1995-06, Vol.249 (4), p.785-799

1995

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Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase

Structure (London), 1999-07, Vol.7 (7), p.733-744

1999

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Ice-free cryo-cooling of protein crystals

Journal of applied crystallography, 1996-08, Vol.29 (4), p.469-470

1996

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Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly

Evolution of an organophosphate-degrading enzyme: a comparison of natural and directed evolution

The α/β hydrolase fold

Of barn owls and bankers: a lush variety of α/β hydrolases

Structure of large fragment of Escherichia coli DNA polymerase I complexed with dTMP

The structure of an enzyme–product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism

Growth of Escherichia coli Coexpressing Phosphotriesterase and Glycerophosphodiester Phosphodiesterase, Using Paraoxon as the Sole Phosphorus Source

Crystal Structure of the N-terminal Domain of the TyrR Transcription Factor Responsible for Gene Regulation of Aromatic Amino Acid Biosynthesis and Transport in Escherichia coli K12

Structure of the C123S mutant of dienelactone hydrolase (DLH) bound with the PMS moiety of the protease inhibitor phenylmethylsulfonyl fluoride (PMSF)

Structure of the Complete Extracellular Domain of the Common β Subunit of the Human GM-CSF, IL-3, and IL-5 Receptors Reveals a Novel Dimer Configuration

Hydrolysis of the 5‘-p-Nitrophenyl Ester of TMP by the Proofreading Exonuclease (ε) Subunit of Escherichia coli DNA Polymerase III

Chloroplast NADP-malate dehydrogenase: structural basis of light-dependent regulation of activity by thiol oxidation and reduction

A novel functional epitope formed by domains 1 and 4 of the human common beta-subunit is involved in receptor activation by granulocyte macrophage colony-stimulating factor and interleukin 5

In Crystallo Capture of a Michaelis Complex and Product-binding Modes of a Bacterial Phosphotriesterase

The two opposing activities of adenylyl transferase reside in distinct homologous domains, with intramolecular signal transduction

The Escherichia coli Signal Transducers PII (GlnB) and GlnK form Heterotrimers in vivo: Fine Tuning the Nitrogen Signal Cascade

The Structure and Function of a Novel Glycerophosphodiesterase from Enterobacter aerogenes

The crystal structure of bikunin from the inter-alpha-inhibitor complex: a serine protease inhibitor with two Kunitz domains

A theoretical study of substrate-induced activation of dienelactone hydrolase

Domain of E. coli DNA polymerase I showing sequence homology to T7 DNA polymerase

An improved resolution structure of the human β common receptor involved in IL-3, IL-5 and GM-CSF signalling which gives better definition of the high-affinity binding epitope

Crystal structure of Escherichia coli QOR quinone oxidoreductase complexed with NADPH

Pyruvate formate lyase is structurally homologous to type I ribonucleotide reductase

Ice-free cryo-cooling of protein crystals

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