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Branched ubiquitin code: from basic biology to targeted protein degradation

Journal of biochemistry (Tokyo), 2022-04, Vol.171 (4), p.361

Ohtake, Fumiaki

2022

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Mass Spectrometry Technologies for Deciphering the Ubiquitin Code

Trends in biochemical sciences (Amsterdam. Regular ed.), 2020-09, Vol.45 (9), p.820-821

Ohtake, Fumiaki

2020

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K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains

Proceedings of the National Academy of Sciences - PNAS, 2018-02, Vol.115 (7), p.E1401-E1408

2018

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The emerging complexity of ubiquitin architecture

Journal of biochemistry (Tokyo), 2017-02, Vol.161 (2), p.125-133

2017

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The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC

Nature cell biology, 2020-06, Vol.22 (6), p.663

2020

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Ubiquitin acetylation inhibits polyubiquitin chain elongation

EMBO reports, 2015-02, Vol.16 (2), p.192-201

2015

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Methods to measure ubiquitin chain length and linkage

Methods in enzymology, 2019, Vol.618, p.105-133

2019

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Ub-ProT reveals global length and composition of protein ubiquitylation in cells

Nature communications, 2018-02, Vol.9 (1), p.524-10, Article 524

2018

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AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

Biochemical pharmacology, 2009-02, Vol.77 (4), p.474-484

2009

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Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways

Development (Cambridge), 2021-10, Vol.148 (19)

2021

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GlcNAcylation of histone H2B facilitates its monoubiquitination

Nature (London), 2011-12, Vol.480 (7378), p.557-560

2011

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Intrinsic signaling pathways modulate targeted protein degradation

Nature communications, 2024-07, Vol.15 (1), p.5379-14, Article 5379

2024

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Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

Nature, 2007-03, Vol.446 (7135), p.562-566

2007

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Critical current density and vortex dynamics in pristine and proton-irradiated Ba0.6K0.4Fe2As2

Superconductor science & technology, 2015-08, Vol.28 (8)

2015

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Cross-talk of dioxin and estrogen receptor signals through the ubiquitin system

The Journal of steroid biochemistry and molecular biology, 2011-10, Vol.127 (1-2), p.102-107

2011

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Senescent cells form nuclear foci that contain the 26S proteasome

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112880-112880, Article 112880

2023

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Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

Communications biology, 2020-04, Vol.3 (1), p.163-163, Article 163

2020

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A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets

Communications biology, 2020-10, Vol.3 (1), p.592-592, Article 592

2020

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Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase

Diabetes (New York, N.Y.), 2013-05, Vol.62 (5), p.1426-1434

2013

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MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL

Communications biology, 2021-01, Vol.4 (1), p.80-80, Article 80

2021

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JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation

The Journal of biological chemistry, 2012-04, Vol.287 (16), p.12994-13004

2012

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The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling

Molecular cell, 2016-10, Vol.64 (2), p.251-266

2016

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The emerging roles of non-canonical ubiquitination in proteostasis and beyond

The Journal of cell biology, 2024-05, Vol.223 (5)

2024

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Epigenetic Silencing of Core Histone Genes by HERS in Drosophila

Molecular cell, 2012-02, Vol.45 (4), p.494-504

2012

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In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome

Molecular cell, 2017-05, Vol.66 (4), p.488-502.e7

2017

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Branched ubiquitin code: from basic biology to targeted protein degradation

Mass Spectrometry Technologies for Deciphering the Ubiquitin Code

K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains

The emerging complexity of ubiquitin architecture

The HOIL-1L ligase modulates immune signalling and cell death via monoubiquitination of LUBAC

Ubiquitin acetylation inhibits polyubiquitin chain elongation

Methods to measure ubiquitin chain length and linkage

Ub-ProT reveals global length and composition of protein ubiquitylation in cells

AhR acts as an E3 ubiquitin ligase to modulate steroid receptor functions

Cleaved Delta like 1 intracellular domain regulates neural development via Notch signal-dependent and -independent pathways

GlcNAcylation of histone H2B facilitates its monoubiquitination

Intrinsic signaling pathways modulate targeted protein degradation

Dioxin receptor is a ligand-dependent E3 ubiquitin ligase

Critical current density and vortex dynamics in pristine and proton-irradiated Ba0.6K0.4Fe2As2

Cross-talk of dioxin and estrogen receptor signals through the ubiquitin system

Senescent cells form nuclear foci that contain the 26S proteasome

Molecular bases for HOIPINs-mediated inhibition of LUBAC and innate immune responses

A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets

Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase

MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL

JMJD5, a Jumonji C (JmjC) Domain-containing Protein, Negatively Regulates Osteoclastogenesis by Facilitating NFATc1 Protein Degradation

The K48-K63 Branched Ubiquitin Chain Regulates NF-κB Signaling

The emerging roles of non-canonical ubiquitination in proteostasis and beyond

Epigenetic Silencing of Core Histone Genes by HERS in Drosophila

In Vivo Ubiquitin Linkage-type Analysis Reveals that the Cdc48-Rad23/Dsk2 Axis Contributes to K48-Linked Chain Specificity of the Proteasome

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