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Polymorphisms in Cha o 1 and Cha o 2, major allergens of Japanese cypress (Chamaecyparis obtusa) pollen from a restricted region in Japan

PloS one, 2021-12, Vol.16 (12), p.e0261327-e0261327

2021

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Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

Cell, 2009-06, Vol.137 (7), p.1235-1246

2009

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Characteristics of object location memory in mice: Behavioral and pharmacological studies

Physiology & behavior, 2007-01, Vol.90 (1), p.116-124

2007

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In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists

The Journal of pharmacology and experimental therapeutics, 2007-10, Vol.323 (1), p.147-156

2007

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Discovery and in vitro and in vivo profiles of 4-fluoro- N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]- N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5464-5468

2009

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Behavioral effects of N -desmethylclozapine on locomotor activity and sensorimotor gating function in mice—Possible involvement of muscarinic receptors

Brain research, 2011-10, Vol.1418, p.111-119

2011

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Regulation of spontaneous Ca2+ spikes by metabotropic glutamate receptors in primary cultures of rat cortical neurons

Journal of neuroscience research, 2010-08, Vol.88 (10), p.2252-2262

2010

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Power spectrum analysis of ultrasonic vocalization elicited by maternal separation in rat pups

Brain research, 2009-08, Vol.1283, p.58-64

2009

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Pharmacological effects of the metabotropic glutamate receptor 1 antagonist compared with those of the metabotropic glutamate receptor 5 antagonist and metabotropic glutamate receptor 2/3 agonist in rodents: detailed investigations with a selective allosteric metabotropic glutamate receptor 1 antagonist, FTIDC [4-[1-(2-fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]

The Journal of pharmacology and experimental therapeutics, 2008-08, Vol.326 (2), p.577-586

2008

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Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: A potential treatment for psychotic disorders

Bioorganic & medicinal chemistry letters, 2009-09, Vol.19 (18), p.5310-5313

2009

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Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

The Journal of pharmacology and experimental therapeutics, 2009-07, Vol.330 (1), p.179

2009

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Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor

Life sciences (1973), 2011-11, Vol.89 (21-22), p.765-772

2011

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Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats — Possible involvement of activation of M₁ muscarinic receptors

European journal of pharmacology, 2011-09, Vol.667 (1-3), p.242-249

2011

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Selective M3 Muscarinic Receptor Antagonist Inhibits Small-Cell Lung Carcinoma Growth in a Mouse Orthotopic Xenograft Model

Journal of Pharmacological Sciences, 2011, Vol.116(1), pp.81-88

2011

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Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC)

The Journal of pharmacology and experimental therapeutics, 2007-06, Vol.321 (3), p.1144-1153

2007

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Synthesis, characterization, and monkey PET studies of [18F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435

Synapse (New York, N.Y.), 2011-02, Vol.65 (2), p.125-135

2011

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Discovery of the First Potent and Selective Small Molecule Opioid Receptor-like (ORL1) Antagonist: 1-[(3R,4R)-1-Cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl- 1,3-dihydro-2H-benzimidazol-2-one (J-113397)

Journal of medicinal chemistry, 1999-12, Vol.42 (25), p.5061-5063

1999

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Corticotropin-releasing factor modulates maternal separation-induced ultrasonic vocalization in rat pups via activation of CRF1 receptor

Brain research, 2008-10, Vol.1234, p.59-65

2008

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In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist

European journal of pharmacology, 2000-08, Vol.402 (1), p.45-53

2000

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Correlation of Receptor Occupancy of Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Mouse Brain With In vivo Activity of Allosteric mGluR1 Antagonists

Journal of Pharmacological Sciences, 2009, Vol.110(3), pp.315-325

2009

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Polymorphisms in Cha o 1 and Cha o 2, major allergens of Japanese cypress

PloS one, 2021-12, Vol.16 (12), p.e0261327

2021

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Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor

European journal of pharmacology, 2008-05, Vol.586 (1-3), p.212-216

2008

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Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome

Genomics data, 2015-09, Vol.5 (C), p.394-396

2015

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Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor

Genes & Genetic Systems, 2009, Vol.84(5), pp.319-325

2009

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Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice

Life sciences (1973), 2004-07, Vol.75 (7), p.869-880

2004

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Polymorphisms in Cha o 1 and Cha o 2, major allergens of Japanese cypress (Chamaecyparis obtusa) pollen from a restricted region in Japan

Abnormal Behavior in a Chromosome- Engineered Mouse Model for Human 15q11-13 Duplication Seen in Autism

Characteristics of object location memory in mice: Behavioral and pharmacological studies

In vitro pharmacological characterization of novel isoxazolopyridone derivatives as allosteric metabotropic glutamate receptor 7 antagonists

Discovery and in vitro and in vivo profiles of 4-fluoro- N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]- N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist

Behavioral effects of N -desmethylclozapine on locomotor activity and sensorimotor gating function in mice—Possible involvement of muscarinic receptors

Regulation of spontaneous Ca2+ spikes by metabotropic glutamate receptors in primary cultures of rat cortical neurons

Power spectrum analysis of ultrasonic vocalization elicited by maternal separation in rat pups

Discovery and biological profile of isoindolinone derivatives as novel metabotropic glutamate receptor 1 antagonists: A potential treatment for psychotic disorders

Unique antipsychotic activities of the selective metabotropic glutamate receptor 1 allosteric antagonist 2-cyclopropyl-5-[1-(2-fluoro-3-pyridinyl)-5-methyl-1H-1,2,3-triazol-4-yl]-2,3-dihydro-1H-isoindol-1-one

Characterization of metabolic phenotypes of mice lacking GPR61, an orphan G-protein coupled receptor

Antipsychotic effects of N-desmethylclozapine on sensorimotor gating function in rats — Possible involvement of activation of M₁ muscarinic receptors

Selective M3 Muscarinic Receptor Antagonist Inhibits Small-Cell Lung Carcinoma Growth in a Mouse Orthotopic Xenograft Model

Pharmacological characterization of a new, orally active and potent allosteric metabotropic glutamate receptor 1 antagonist, 4-[1-(2-fluoropyridin-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide (FTIDC)

Synthesis, characterization, and monkey PET studies of [18F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435

Discovery of the First Potent and Selective Small Molecule Opioid Receptor-like (ORL1) Antagonist: 1-[(3R,4R)-1-Cyclooctylmethyl-3- hydroxymethyl-4-piperidyl]-3-ethyl- 1,3-dihydro-2H-benzimidazol-2-one (J-113397)

Corticotropin-releasing factor modulates maternal separation-induced ultrasonic vocalization in rat pups via activation of CRF1 receptor

In vitro and in vivo pharmacological characterization of J-113397, a potent and selective non-peptidyl ORL1 receptor antagonist

Correlation of Receptor Occupancy of Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Mouse Brain With In vivo Activity of Allosteric mGluR1 Antagonists

Polymorphisms in Cha o 1 and Cha o 2, major allergens of Japanese cypress

Face-washing behavior induced by the group I metabotropic glutamate receptor agonist (S)-3,5-DHPG in mice is mediated by mGlu1 receptor

Transcriptome profiling of white adipose tissue in a mouse model for 15q duplication syndrome

Cloning and characterization of the rhesus monkey nociceptin/orphanin FQ receptor

Losartan ameliorates progression of glomerular structural changes in diabetic KKAy mice

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