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Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

Cancer science, 2012-06, Vol.103 (6), p.1099-1104

2012

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Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors

Molecular pharmacology, 2003-10, Vol.64 (4), p.994-1005

2003

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Lysophosphatidic Acid (LPA) in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells through LPA1

The Journal of biological chemistry, 2004-02, Vol.279 (8), p.6595-6605

2004

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Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Biochemical journal, 2000-05, Vol.348 Pt 1 (1), p.71-76

2000

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Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells

American journal of physiology. Heart and circulatory physiology, 2007-05, Vol.292 (5), p.H2513-H2522

2007

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Comparison of Intrinsic Activities of the Putative Sphingosine 1-Phosphate Receptor Subtypes to Regulate Several Signaling Pathways in Their cDNA-transfected Chinese Hamster Ovary Cells

The Journal of biological chemistry, 1999-08, Vol.274 (34), p.23940-23947

1999

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Edg-6 as a Putative Sphingosine 1-Phosphate Receptor Coupling to Ca2+ Signaling Pathway

Biochemical and biophysical research communications, 2000-02, Vol.268 (2), p.583-589

2000

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Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells

Experimental cell research, 2004-12, Vol.301 (2), p.168-178

2004

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Lysophosphatidic Acid (LPA)-Induced Vascular Endothelial Growth Factor (VEGF) by Mesothelial Cells and Quantification of Host-Derived VEGF in Malignant Ascites

The Journal of surgical research, 2006, Vol.130 (1), p.94-101

2006

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Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells

The Journal of immunology (1950), 2008-10, Vol.181 (7), p.5111-5119

2008

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LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites

Carcinogenesis (New York), 2009-03, Vol.30 (3), p.457-465

2009

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Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1

The Journal of biological chemistry, 2004-04, Vol.279 (17), p.17634-17639

2004

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Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells

Biochemical and biophysical research communications, 1998-12, Vol.253 (2), p.253-256

1998

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Development and Pack Cycle Simulation of High Power Li-ion Batteries

Denki kagaku oyobi kōgyō butsuri kagaku, 2003-12, Vol.71 (12), p.1090-1092

2003

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p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1

Cardiovascular research, 2011-10, Vol.92 (1), p.149-158

2011

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Sperm Motility-Initiating Activity in the Egg Jelly of the Externally-Fertilizing Urodele Amphibian, Hynobius lichenatus

Zoological Science, 2010-11, Vol.27 (11), p.875-879

2010

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Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

Biochemical and biophysical research communications, 2000-02, Vol.268 (2), p.583-589

2000

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Complexation of a disulfide-linked α-cyclodextrin dimer with 1-alkanols

Journal of molecular structure, 2008-11, Vol.891 (1), p.420-422

2008

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Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart

European journal of pharmacology, 1991-11, Vol.204 (2), p.171-177

1991

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Multiple inflammatory pseudotumors mimicking liver metastasis from colon cancer: report of a case

Surgery today (Tokyo, Japan), 2000-01, Vol.30 (6), p.530-533

2000

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Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Biochemical journal, 2000-05, Vol.348 (1), p.71-76

2000

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Effects of the K+ Channel Opener KRN4884 on the Cardiovascular Metabolic Syndrome Model in Rats

Journal of cardiovascular pharmacology, 2000-02, Vol.35 (2), p.287-293

2000

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Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells

Vascular pharmacology, 2009-05, Vol.50 (5), p.178-184

2009

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Contribution of cyclic GMP formation to KRN2391‐induced relaxation in coronary artery of the pig

British journal of pharmacology, 1992-08, Vol.106 (4), p.906-909

1992

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Relationship between myoglobin contents and increases in cyclic GMP produced by glyceryl trinitrate and nitric oxide in rabbit aorta, right atrium and papillary muscle

Naunyn-Schmiedeberg's archives of pharmacology, 1993-05, Vol.347 (5), p.553-561

1993

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Orally active lysophosphatidic acid receptor antagonist attenuates pancreatic cancer invasion and metastasis in vivo

Ki16425, a Subtype-Selective Antagonist for EDG-Family Lysophosphatidic Acid Receptors

Lysophosphatidic Acid (LPA) in Malignant Ascites Stimulates Motility of Human Pancreatic Cancer Cells through LPA1

Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Role of lipoprotein-associated lysophospholipids in migratory activity of coronary artery smooth muscle cells

Comparison of Intrinsic Activities of the Putative Sphingosine 1-Phosphate Receptor Subtypes to Regulate Several Signaling Pathways in Their cDNA-transfected Chinese Hamster Ovary Cells

Edg-6 as a Putative Sphingosine 1-Phosphate Receptor Coupling to Ca2+ Signaling Pathway

Dual mode regulation of migration by lysophosphatidic acid in human gastric cancer cells

Lysophosphatidic Acid (LPA)-Induced Vascular Endothelial Growth Factor (VEGF) by Mesothelial Cells and Quantification of Host-Derived VEGF in Malignant Ascites

Stimulatory Role of Lysophosphatidic Acid in Cyclooxygenase-2 Induction by Synovial Fluid of Patients with Rheumatoid Arthritis in Fibroblast-Like Synovial Cells

LPA1 receptors mediate stimulation, whereas LPA2 receptors mediate inhibition, of migration of pancreatic cancer cells in response to lysophosphatidic acid and malignant ascites

Lysophosphatidic Acid and Autotaxin Stimulate Cell Motility of Neoplastic and Non-neoplastic Cells through LPA1

Downregulation of mRNA Expression of Edg-3, a Putative Sphingosine 1-Phosphate Receptor Coupled to Ca2+Signaling, during Differentiation of HL-60 Leukemia Cells

Development and Pack Cycle Simulation of High Power Li-ion Batteries

p2y5/LPA(6) attenuates LPA(1)-mediated VE-cadherin translocation and cell-cell dissociation through G(12/13) protein-Src-Rap1

Sperm Motility-Initiating Activity in the Egg Jelly of the Externally-Fertilizing Urodele Amphibian, Hynobius lichenatus

Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway

Complexation of a disulfide-linked α-cyclodextrin dimer with 1-alkanols

Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart

Multiple inflammatory pseudotumors mimicking liver metastasis from colon cancer: report of a case

Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

Effects of the K+ Channel Opener KRN4884 on the Cardiovascular Metabolic Syndrome Model in Rats

Signaling pathways involved in DNA synthesis and migration in response to lysophosphatidic acid and low-density lipoprotein in coronary artery smooth muscle cells

Contribution of cyclic GMP formation to KRN2391‐induced relaxation in coronary artery of the pig

Relationship between myoglobin contents and increases in cyclic GMP produced by glyceryl trinitrate and nitric oxide in rabbit aorta, right atrium and papillary muscle

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