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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Malaria journal, 2012-08, Vol.11 (1), p.259-259, Article 259

2012

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A randomized, double-blind, active-control trial to evaluate the efficacy and safety of a three day course of tafenoquine monotherapy for the treatment of Plasmodium vivax malaria

PloS one, 2017-11, Vol.12 (11), p.e0187376

2017

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The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

Malaria journal, 2013-06, Vol.12 (1), p.212-212, Article 212

2013

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Risk factor assessment for clinical malaria among forest-goers in a pre-elimination setting in Phu Yen Province, Vietnam

Malaria journal, 2019-12, Vol.18 (1), p.435-435, Article 435

2019

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Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (43), p.17486-17491

2013

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Randomized, Double-Blind Study of the Safety, Tolerability, and Efficacy of Tafenoquine versus Mefloquine for Malaria Prophylaxis in Nonimmune Subjects

Antimicrobial Agents and Chemotherapy, 2010-02, Vol.54 (2), p.792-798

2010

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Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta)

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7283-7291

2014

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Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)

Malaria journal, 2011-07, Vol.10 (1), p.212-212, Article 212

2011

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Comparison of visual and automated Deki Reader interpretation of malaria rapid diagnostic tests in rural Tanzanian military health facilities

Malaria journal, 2018-05, Vol.17 (1), p.214-214, Article 214

2018

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Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro

Antimicrobial Agents and Chemotherapy, 2002-08, Vol.46 (8), p.2518-2524

2002

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Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers

Antimicrobial agents and chemotherapy, 2014-08, Vol.58 (8), p.4737-4744

2014

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Azithromycin Combination Therapy with Artesunate or Quinine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Adults: A Randomized, Phase 2 Clinical Trial in Thailand

Clinical infectious diseases, 2006-11, Vol.43 (10), p.1264-1271

2006

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In Vitro Antimalarial Activity of Azithromycin, Artesunate, and Quinine in Combination and Correlation with Clinical Outcome

Antimicrobial Agents and Chemotherapy, 2007-02, Vol.51 (2), p.651-656

2007

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A New Primaquine Analogue, Tafenoquine (WR 238605), for Prophylaxis against Plasmodium falciparum Malaria

Clinical infectious diseases, 2001-12, Vol.33 (12), p.1968-1974

2001

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Absolute Bioavailability of cis-Mirincamycin and trans-Mirincamycin in Healthy Rhesus Monkeys and Ex Vivo Antimalarial Activity against Plasmodium falciparum

Antimicrobial Agents and Chemotherapy, 2011-12, Vol.55 (12), p.5881-5886

2011

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Establishing a malaria diagnostics centre of excellence in Kisumu, Kenya

Malaria journal, 2007-06, Vol.6 (1), p.79-79, Article 79

2007

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Use of a Rhesus Plasmodium cynomolgi Model to Screen for Anti-Hypnozoite Activity of Pharmaceutical Substances

The American journal of tropical medicine and hygiene, 2012-06, Vol.86 (6), p.931-935

2012

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Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria

Malaria journal, 2008-12, Vol.7 (1), p.259-259, Article 259

2008

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Pilot assessment of the sensitivity of the malaria thin film

Malaria journal, 2008-01, Vol.7 (1), p.22-22, Article 22

2008

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Tackling imported malaria: an elimination endgame

The American journal of tropical medicine and hygiene, 2015-07, Vol.93 (1), p.139-144

2015

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Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki

Therapeutics and clinical risk management, 2008-08, Vol.4 (4), p.803-819

2008

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Malaria Prophylaxis Using Azithromycin: A Double-Blind, Placebo-Controlled Trial in Irian Jaya, Indonesia

Clinical infectious diseases, 1999-01, Vol.28 (1), p.74-81

1999

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Field evaluation of diagnostic performance of malaria rapid diagnostic tests in western Kenya

Malaria journal, 2016-09, Vol.15 (1), p.456-456, Article 456

2016

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Information systems to support surveillance for malaria elimination

The American journal of tropical medicine and hygiene, 2015-07, Vol.93 (1), p.145-152

2015

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CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

A randomized, double-blind, active-control trial to evaluate the efficacy and safety of a three day course of tafenoquine monotherapy for the treatment of Plasmodium vivax malaria

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

Risk factor assessment for clinical malaria among forest-goers in a pre-elimination setting in Phu Yen Province, Vietnam

Humanized mouse model of glucose 6-phosphate dehydrogenase deficiency for in vivo assessment of hemolytic toxicity

The use of Fionet technology for external quality control of malaria rapid diagnostic tests and monitoring health workers' performance in rural military health facilities in Tanzania

Randomized, Double-Blind Study of the Safety, Tolerability, and Efficacy of Tafenoquine versus Mefloquine for Malaria Prophylaxis in Nonimmune Subjects

Pharmacokinetics and pharmacodynamics of (+)-primaquine and (-)-primaquine enantiomers in rhesus macaques (Macaca mulatta)

Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta)

Comparison of visual and automated Deki Reader interpretation of malaria rapid diagnostic tests in rural Tanzanian military health facilities

Assessment of Azithromycin in Combination with Other Antimalarial Drugs against Plasmodium falciparum In Vitro

Scalable Preparation and Differential Pharmacologic and Toxicologic Profiles of Primaquine Enantiomers

Azithromycin Combination Therapy with Artesunate or Quinine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Adults: A Randomized, Phase 2 Clinical Trial in Thailand

In Vitro Antimalarial Activity of Azithromycin, Artesunate, and Quinine in Combination and Correlation with Clinical Outcome

A New Primaquine Analogue, Tafenoquine (WR 238605), for Prophylaxis against Plasmodium falciparum Malaria

Absolute Bioavailability of cis-Mirincamycin and trans-Mirincamycin in Healthy Rhesus Monkeys and Ex Vivo Antimalarial Activity against Plasmodium falciparum

Establishing a malaria diagnostics centre of excellence in Kisumu, Kenya

Use of a Rhesus Plasmodium cynomolgi Model to Screen for Anti-Hypnozoite Activity of Pharmaceutical Substances

Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria

Pilot assessment of the sensitivity of the malaria thin film

Tackling imported malaria: an elimination endgame

Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki

Malaria Prophylaxis Using Azithromycin: A Double-Blind, Placebo-Controlled Trial in Irian Jaya, Indonesia

Field evaluation of diagnostic performance of malaria rapid diagnostic tests in western Kenya

Information systems to support surveillance for malaria elimination

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