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Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway

PloS one, 2023-02, Vol.18 (2), p.e0281414-e0281414

2023

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ASC amino acid transporter 2, defined by enzyme‐mediated activation of radical sources, enhances malignancy of GD2‐positive small‐cell lung cancer

Cancer science, 2018-01, Vol.109 (1), p.141-153

2018

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Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

Cancer science, 2021-09, Vol.112 (9), p.3756-3768

2021

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New era of research on cancer‐associated glycosphingolipids

Cancer science, 2019-05, Vol.110 (5), p.1544-1551

2019

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Differential roles of gangliosides in malignant properties of melanomas

PloS one, 2018-11, Vol.13 (11), p.e0206881-e0206881

2018

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Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

Nature communications, 2016-04, Vol.7 (1), p.11205-11205, Article 11205

2016

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Signaling domains of cancer-associated glycolipids

Glycoconjugate journal, 2022-04, Vol.39 (2), p.145-155

2022

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Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

PLoS biology, 2018-11, Vol.16 (11), p.e2006951

2018

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Elucidation of Pathological Mechanisms for Involvement of Gangliosides in Intractable Diseases

Trends in Glycoscience and Glycotechnology, 2020/05/25, Vol.32(187), pp.E81-E86

2020

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Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia

Journal of biochemistry (Tokyo), 2020-08, Vol.168 (2), p.103

2020

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Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling

Anticancer research, 2021-04, Vol.41 (4), p.1821-1830

2021

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Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice

Journal of neurochemistry, 2011-03, Vol.116 (5), p.926-935

2011

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Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD2

International journal of oncology, 2018-04, Vol.52 (4), p.1255-1266

2018

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Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas

Scientific reports, 2023-03, Vol.13 (1), p.4987-4987, Article 4987

2023

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Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

International journal of molecular sciences, 2021-12, Vol.23 (1), p.423

2021

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Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration — Great progress over the last 70 years

Proceedings of the Japan Academy, Series B, 2019/03/11, Vol.95(3), pp.136-149

2019

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Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains

The Journal of biological chemistry, 2010-08, Vol.285 (35), p.27213-27223

2010

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Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells

The Journal of biological chemistry, 2016-08, Vol.291 (32), p.16630-16643

2016

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Essential Roles of Gangliosides in the Formation and Maintenance of Membrane Microdomains in Brain Tissues

Neurochemical research, 2012-06, Vol.37 (6), p.1185-1191

2012

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Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (52), p.22405-22410

2009

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Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering

International journal of molecular sciences, 2020-03, Vol.21 (6), p.1906

2020

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Regulatory function of glycosphingolipids in the inflammation and degeneration

Archives of biochemistry and biophysics, 2015-04, Vol.571, p.58-65

2015

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Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene

FEBS open bio, 2023-09, Vol.13 (9), p.1615-1624

2023

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Expression of B4GALNT1, an essential glycosyltransferase for the synthesis of complex gangliosides, suppresses BACE1 degradation and modulates APP processing

Scientific reports, 2016-09, Vol.6 (1), p.34505-34505, Article 34505

2016

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Fine tuning of cell signals by glycosylation

Journal of biochemistry (Tokyo), 2012-06, Vol.151 (6), p.573-578

2012

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Ganglioside GM3 prevents high fat diet-induced hepatosteatosis via attenuated insulin signaling pathway

ASC amino acid transporter 2, defined by enzyme‐mediated activation of radical sources, enhances malignancy of GD2‐positive small‐cell lung cancer

Lack of GD3 synthase (St8sia1) attenuates malignant properties of gliomas in genetically engineered mouse model

New era of research on cancer‐associated glycosphingolipids

Differential roles of gangliosides in malignant properties of melanomas

Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis

Signaling domains of cancer-associated glycolipids

Genome-wide CRISPR screens for Shiga toxins and ricin reveal Golgi proteins critical for glycosylation

Elucidation of Pathological Mechanisms for Involvement of Gangliosides in Intractable Diseases

Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia

Lewis y Expressed in Oral Squamous Cell Carcinoma Attenuates Malignant Properties via Down-regulation of EGF Signaling

Gangliosides are essential in the protection of inflammation and neurodegeneration via maintenance of lipid rafts: elucidation by a series of ganglioside-deficient mutant mice

Enhancement of malignant properties of human glioma cells by ganglioside GD3/GD2

Extracellular vesicles released from ganglioside GD2-expressing melanoma cells enhance the malignant properties of GD2-negative melanomas

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Elucidation of the enigma of glycosphingolipids in the regulation of inflammation and degeneration — Great progress over the last 70 years

Ganglioside GD3 Enhances Adhesion Signals and Augments Malignant Properties of Melanoma Cells by Recruiting Integrins to Glycolipid-enriched Microdomains

Neogenin, Defined as a GD3-associated Molecule by Enzyme-mediated Activation of Radical Sources, Confers Malignant Properties via Intracytoplasmic Domain in Melanoma Cells

Essential Roles of Gangliosides in the Formation and Maintenance of Membrane Microdomains in Brain Tissues

Gangliosides play pivotal roles in the regulation of complement systems and in the maintenance of integrity in nerve tissues

Novel Molecular Mechanisms of Gangliosides in the Nervous System Elucidated by Genetic Engineering

Regulatory function of glycosphingolipids in the inflammation and degeneration

Disordered testosterone transport in mice lacking the ganglioside GM2/GD2 synthase gene

Expression of B4GALNT1, an essential glycosyltransferase for the synthesis of complex gangliosides, suppresses BACE1 degradation and modulates APP processing

Fine tuning of cell signals by glycosylation

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