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Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia

Medicinal research reviews, 2001-03, Vol.21 (2), p.129-145

2001

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Inhibition of Extracellular Signal–Regulated Kinase Enhances Ischemia/Reoxygenation–Induced Apoptosis in Cultured Cardiac Myocytes and Exaggerates Reperfusion Injury in Isolated Perfused Heart

Circulation research, 2000-03, Vol.86 (6), p.692-699

2000

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SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia

The Journal of pharmacology and experimental therapeutics, 2001-02, Vol.296 (2), p.312

2001

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Contractile responses to human urotensin‐II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat

British journal of pharmacology, 2000-05, Vol.130 (2), p.201-204

2000

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Myocardial protection from ischemia/reperfusion injury by targeted deletion of matrix metalloproteinase-9

Cardiovascular research, 2002-06, Vol.54 (3), p.549-558

2002

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Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

British journal of pharmacology, 2008-10, Vol.155 (3), p.374-386

2008

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Endothelin levels increase in rat focal and global ischemia

Journal of cerebral blood flow and metabolism, 1994-03, Vol.14 (2), p.337-342

1994

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Expression of Endothelin-1, Endothelin-3, Endothelin-Converting Enzyme-1, and Endothelin-A and Endothelin-B Receptor mRNA After Angioplasty-Induced Neointimal Formation in the Rat

Circulation research, 1996-02, Vol.78 (2), p.322-328

1996

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Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle

The Journal of pharmacology and experimental therapeutics, 1994-10, Vol.271 (1), p.429

1994

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Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients

American journal of physiology. Renal physiology, 2001-08, Vol.281 (2), p.F309-F317

2001

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In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone

Circulation (New York, N.Y.), 2001-11, Vol.104 (21), p.2588-2594

2001

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Signal transduction mechanisms mediating the vascular actions of endothelin

Journal of vascular research, 1997-05, Vol.34 (3), p.152-164

1997

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Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

Stroke (1970), 1998-05, Vol.29 (5), p.1020-1030

1998

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Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells

Journal of neurosurgery, 1992-08, Vol.77 (2), p.274-278

1992

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Activation of peroxisome proliferator-activated receptor-α protects the heart from ischemia/reperfusion injury

Circulation (New York, N.Y.), 2003-11, Vol.108 (19), p.2393-2399

2003

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Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey

British journal of pharmacology, 2000-12, Vol.131 (7), p.1262-1274

2000

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Human Urotensin-II, the Most Potent Mammalian Vasoconstrictor Identified To Date, as a Therapeutic Target for the Management of Cardiovascular Disease

Trends in Cardiovascular Medicine, 2000-08, Vol.10 (6), p.229-237

2000

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A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670

Circulation research, 1994-07, Vol.75 (1), p.190-197

1994

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SB 209670, a Rationally Designed Potent Nonpeptide Endothelin Receptor Antagonist

Proceedings of the National Academy of Sciences - PNAS, 1994-08, Vol.91 (17), p.8052-8056

1994

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Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries

American journal of physiology. Heart and circulatory physiology, 2001-02, Vol.280 (2), p.H925-H928

2001

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A Comparison of Carvedilol and Metoprolol Antioxidant Activities In Vitro

Journal of cardiovascular pharmacology, 2000-08, Vol.36 (2), p.277-281

2000

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Cellular mechanisms of endothelin in rabbit aorta

The Journal of pharmacology and experimental therapeutics, 1989-08, Vol.250 (2), p.548

1989

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Carvedilol, a Cardiovascular Drug, Prevents Vascular Smooth Muscle Cell Proliferation, Migration, and Neointimal Formation Following Vascular Injury

Proceedings of the National Academy of Sciences - PNAS, 1993-07, Vol.90 (13), p.6189-6193

1993

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Rabbit Polymorphonuclear Neutrophils Elicit Endothelium-Dependent Contraction in Vascular Smooth Muscle

Circulation research, 1989-10, Vol.65 (4), p.917-924

1989

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Renal microvascular effects of endothelin

American journal of physiology. Renal physiology, 1990-08, Vol.259 (2), p.217-F221

1990

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Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia

Inhibition of Extracellular Signal–Regulated Kinase Enhances Ischemia/Reoxygenation–Induced Apoptosis in Cultured Cardiac Myocytes and Exaggerates Reperfusion Injury in Isolated Perfused Heart

SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia

Contractile responses to human urotensin‐II in rat and human pulmonary arteries: effect of endothelial factors and chronic hypoxia in the rat

Myocardial protection from ischemia/reperfusion injury by targeted deletion of matrix metalloproteinase-9

Palosuran inhibits binding to primate UT receptors in cell membranes but demonstrates differential activity in intact cells and vascular tissues

Endothelin levels increase in rat focal and global ischemia

Expression of Endothelin-1, Endothelin-3, Endothelin-Converting Enzyme-1, and Endothelin-A and Endothelin-B Receptor mRNA After Angioplasty-Induced Neointimal Formation in the Rat

Angiotensin type 1 receptors mediate smooth muscle proliferation and endothelin biosynthesis in rat vascular smooth muscle

Upregulated expression of human membrane type-5 matrix metalloproteinase in kidneys from diabetic patients

In vivo myocardial protection from ischemia/reperfusion injury by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone

Signal transduction mechanisms mediating the vascular actions of endothelin

Matrix metalloproteinase expression increases after cerebral focal ischemia in rats: inhibition of matrix metalloproteinase-9 reduces infarct size

Oxyhemoglobin stimulation of endothelin production in cultured endothelial cells

Activation of peroxisome proliferator-activated receptor-α protects the heart from ischemia/reperfusion injury

Differential vasoconstrictor activity of human urotensin‐II in vascular tissue isolated from the rat, mouse, dog, pig, marmoset and cynomolgus monkey

Human Urotensin-II, the Most Potent Mammalian Vasoconstrictor Identified To Date, as a Therapeutic Target for the Management of Cardiovascular Disease

A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Protective effects of the novel nonpeptide endothelin receptor antagonist SB 209670

SB 209670, a Rationally Designed Potent Nonpeptide Endothelin Receptor Antagonist

Potent vasodilator responses to human urotensin-II in human pulmonary and abdominal resistance arteries

A Comparison of Carvedilol and Metoprolol Antioxidant Activities In Vitro

Cellular mechanisms of endothelin in rabbit aorta

Carvedilol, a Cardiovascular Drug, Prevents Vascular Smooth Muscle Cell Proliferation, Migration, and Neointimal Formation Following Vascular Injury

Rabbit Polymorphonuclear Neutrophils Elicit Endothelium-Dependent Contraction in Vascular Smooth Muscle

Renal microvascular effects of endothelin

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