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The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

Pulmonary pharmacology & therapeutics, 2008-01, Vol.21 (2), p.360-369

2008

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Synthesis and evaluation of 2-{[2-(4-hydroxyphenyl)-ethyl]amino}pyrimidine-5-carboxamide derivatives as novel STAT6 inhibitors

Bioorganic & medicinal chemistry, 2007-01, Vol.15 (2), p.1044-1055

2007

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A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes

The Journal of immunology (1950), 2003-05, Vol.170 (9), p.4441-4449

2003

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YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models

European journal of pharmacology, 2007-04, Vol.560 (2), p.225-233

2007

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In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors

The Journal of pharmacology and experimental therapeutics, 1998-11, Vol.287 (2), p.633

1998

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Effect of combined leukotriene D4 and thromboxane A2 receptor antagonist on mediator-controlled resistance in guinea pigs

European journal of pharmacology, 2000-09, Vol.403 (1-2), p.169-179

2000

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Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

Bioorganic & medicinal chemistry, 2009-10, Vol.17 (19), p.6926-6936

2009

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YM-341619 suppresses the differentiation of spleen T cells into Th2 cells in vitro, eosinophilia, and airway hyperresponsiveness in rat allergic models

European journal of pharmacology, 2008-08, Vol.590 (1), p.409-416

2008

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Binding of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors, to guinea pig lung membranes

European journal of pharmacology, 1998-12, Vol.362 (2-3), p.229-233

1998

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Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs

The Journal of pharmacology and experimental therapeutics, 1999-09, Vol.290 (3), p.1285

1999

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Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

International immunopharmacology, 2008-12, Vol.8 (13-14), p.1787-1792

2008

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Characterization of YM-58483/BTP2, a novel store-operated Ca super(2+) entry blocker, on T cell-mediated immune responses in vivo

International immunopharmacology, 2008-12, Vol.8 (13-14), p.1787-1792

2008

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Characterization of YM-58483/BTP2, a novel store-operated Ca 2+ entry blocker, on T cell-mediated immune responses in vivo

International immunopharmacology, 2008, Vol.8 (13), p.1787-1792

2008

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A Business Intelligence Solution to Pharmacovigilance Signal Tracking and Management: One Mid-Size Pharma’s Experience

Pharmaceutical medicine, 2015-08, Vol.29 (4), p.197-201

2015

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Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors

Bioorganic & medicinal chemistry, 2008-07, Vol.16 (13), p.6509-6521

2008

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Concept of Routine Pharmacovigilance, Especially Signal Management in the US and Europe

Japanese journal of pharmacoepidemiology, 2021-09, Vol.26 (2), p.115-126, Article 26.e6

2021

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Novel 7 H-pyrrolo[2,3- d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

Bioorganic & medicinal chemistry, 2009, Vol.17 (19), p.6926-6936

2009

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The suppressive effects of YM-58483/BTP-2, a store-operated Ca 2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

Pulmonary pharmacology & therapeutics, 2008, Vol.21 (2), p.360-369

2008

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Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs

The Journal of pharmacology and experimental therapeutics, 2001-04, Vol.297 (1), p.165

2001

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YM-58483, a selective CRAC channel inhibitor, prevents late-phase asthmatic responses through Th2 cytokine inhibition in animal models

Journal of Pharmacological Sciences, 2005, Vol.97 (suppl.2), p.224-224

2005

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Effect of YM158, a Dual Lipid Mediator Antagonist, on Immediate and Late Asthmatic Responses, and on Airway Hyper-responsiveness in Guinea Pigs

The Japanese Journal of Pharmacology, 2000, Vol.82(4), pp.287-294

2000

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In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors

Japanese journal of pharmacology, 2000-05, Vol.83 (1), p.63-72

2000

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Effect of combined leukotriene D4 and thromboxane A2receptor antagonist on mediator-controlled resistance in guinea pigs

European journal of pharmacology, 2000, Vol.403 (1-2), p.169-179

2000

Volltextzugriff (PDF)

Effect of combined leukotriene D 4 and thromboxane A 2 receptor antagonist on mediator-controlled resistance in guinea pigs

European journal of pharmacology, 2000, Vol.403 (1), p.169-179

2000

Volltextzugriff (PDF)

In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors

The Japanese Journal of Pharmacology, 2000, Vol.83(1), pp.63-72

2000

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The suppressive effects of YM-58483/BTP-2, a store-operated Ca2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

Synthesis and evaluation of 2-{[2-(4-hydroxyphenyl)-ethyl]amino}pyrimidine-5-carboxamide derivatives as novel STAT6 inhibitors

A Pyrazole Derivative, YM-58483, Potently Inhibits Store-Operated Sustained Ca2+ Influx and IL-2 Production in T Lymphocytes

YM-58483, a selective CRAC channel inhibitor, prevents antigen-induced airway eosinophilia and late phase asthmatic responses via Th2 cytokine inhibition in animal models

In vitro pharmacologic profile of YM158, a new dual antagonist for LTD4 and TXA2 receptors

Effect of combined leukotriene D4 and thromboxane A2 receptor antagonist on mediator-controlled resistance in guinea pigs

Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

YM-341619 suppresses the differentiation of spleen T cells into Th2 cells in vitro, eosinophilia, and airway hyperresponsiveness in rat allergic models

Binding of YM158, a new dual antagonist for leukotriene D4 and thromboxane A2 receptors, to guinea pig lung membranes

Effects of lipid mediator antagonists on predominant mediator-controlled asthmatic reactions in passively sensitized guinea pigs

Characterization of YM-58483/BTP2, a novel store-operated Ca2+ entry blocker, on T cell-mediated immune responses in vivo

Characterization of YM-58483/BTP2, a novel store-operated Ca super(2+) entry blocker, on T cell-mediated immune responses in vivo

Characterization of YM-58483/BTP2, a novel store-operated Ca 2+ entry blocker, on T cell-mediated immune responses in vivo

A Business Intelligence Solution to Pharmacovigilance Signal Tracking and Management: One Mid-Size Pharma’s Experience

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors

Concept of Routine Pharmacovigilance, Especially Signal Management in the US and Europe

Novel 7 H-pyrrolo[2,3- d]pyrimidine derivatives as potent and orally active STAT6 inhibitors

The suppressive effects of YM-58483/BTP-2, a store-operated Ca 2+ entry blocker, on inflammatory mediator release in vitro and airway responses in vivo

Antiasthmatic effect of YM976, a novel PDE4 inhibitor, in guinea pigs

YM-58483, a selective CRAC channel inhibitor, prevents late-phase asthmatic responses through Th2 cytokine inhibition in animal models

Effect of YM158, a Dual Lipid Mediator Antagonist, on Immediate and Late Asthmatic Responses, and on Airway Hyper-responsiveness in Guinea Pigs

In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors

Effect of combined leukotriene D4 and thromboxane A2receptor antagonist on mediator-controlled resistance in guinea pigs

Effect of combined leukotriene D 4 and thromboxane A 2 receptor antagonist on mediator-controlled resistance in guinea pigs

In Vivo Pharmacologic Profile of YM158, a New Dual Antagonist for Leukotriene D4 and Thromboxane A2 Receptors

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