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Receptor Tyrosine Kinase-Targeted Cancer Therapy

International journal of molecular sciences, 2018-11, Vol.19 (11), p.3491

2018

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Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms

International journal of molecular sciences, 2017-11, Vol.18 (11), p.2420

2017

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Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation

Molecular cancer research, 2017-07, Vol.15 (7), p.915-928

2017

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KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR

Molecular cancer therapeutics, 2019-01, Vol.18 (1), p.112-126

2019

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Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury

International journal of molecular sciences, 2019-08, Vol.20 (16), p.4021

2019

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Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation

Molecular cancer therapeutics, 2016-12, Vol.15 (12), p.3040-3054

2016

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Lysophosphatidylcholine Activates Adipocyte Glucose Uptake and Lowers Blood Glucose Levels in Murine Models of Diabetes

The Journal of biological chemistry, 2009-12, Vol.284 (49), p.33833-33840

2009

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Novel Anti-FOLR1 Antibody-Drug Conjugate MORAb-202 in Breast Cancer and Non-Small Cell Lung Cancer Cells

Antibodies (Basel), 2021-02, Vol.10 (1), p.6

2021

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B lymphocyte-induced maturation protein 1 is a novel target gene of aryl hydrocarbon receptor

Journal of dermatological science, 2010-06, Vol.58 (3), p.211-216

2010

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Silver Nanoscale Hexagonal Column Chips for Detecting Cell-free DNA and Circulating Nucleosomes in Cancer Patients

Scientific reports, 2015-05, Vol.5 (1), p.10455-10455, Article 10455

2015

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Functional Characterization of IL-17F as a Selective Neutrophil Attractant in Psoriasis

Journal of investigative dermatology, 2009-03, Vol.129 (3), p.650-656

2009

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Up-regulation of Syndecan-4 contributes to TGF-β1-induced epithelial to mesenchymal transition in lung adenocarcinoma A549 cells

Biochemistry and biophysics reports, 2016-03, Vol.5 (C), p.1-7

2016

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Activation of Proteinase-Activated Receptor 2 Stimulates Soluble Vascular Endothelial Growth Factor Receptor 1 Release via Epidermal Growth Factor Receptor Transactivation in Endothelial Cells

Hypertension (Dallas, Tex. 1979), 2010-03, Vol.55 (3), p.689-697

2010

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Distinct Mechanisms of Receptor and Nonreceptor Tyrosine Kinase Activation by Reactive Oxygen Species in Vascular Smooth Muscle Cells: Role of Metalloprotease and Protein Kinase C-δ

Molecular and Cellular Biology, 2003-03, Vol.23 (5), p.1581-1589

2003

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Induction of Differentiation in Normal Human Keratinocytes by Adenovirus-Mediated Introduction of the η and δ Isoforms of Protein Kinase C

Molecular and Cellular Biology, 1998-09, Vol.18 (9), p.5199-5207

1998

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Activation of Protein Kinase Cζ Induces Serine Phosphorylation of VAMP2 in the GLUT4 Compartment and Increases Glucose Transport in Skeletal Muscle

Molecular and Cellular Biology, 2001-11, Vol.21 (22), p.7852-7861

2001

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Novel Functions of the Phospholipase D2-Phox Homology Domain in Protein Kinase Cζ Activation

Molecular and Cellular Biology, 2005-04, Vol.25 (8), p.3194-3208

2005

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Protein kinase C eta (PKC eta): its involvement in keratinocyte differentiation

Journal of biochemistry (Tokyo), 2002-12, Vol.132 (6), p.853

2002

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Abstract 2113: KRAS amplification mediates resistance to osimertinib in acquired afatinib-resistant NSCLC harboring exon 19 deletion/T790M in EGFR

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.2113-2113

2019

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Role of CPI-17 in the regulation of endothelial cytoskeleton

American journal of physiology. Lung cellular and molecular physiology, 2004-11, Vol.287 (5), p.L970-L980

2004

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Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: implications for epidermal growth factor signaling

Molecular biology of the cell, 2002-11, Vol.13 (11), p.3976-3988

2002

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PKCη associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes

Oncogene, 2000-12, Vol.19 (54), p.6334-6341

2000

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PKC δ mediates ionizing radiation-induced activation of c-Jun NH2-terminal kinase through MKK7 in human thyroid cells

Oncogene, 2001-02, Vol.20 (8), p.989-996

2001

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Vascular Endothelial Tight Junctions and Barrier Function Are Disrupted by 15(S)-Hydroxyeicosatetraenoic Acid Partly via Protein Kinase Cϵ-mediated Zona Occludens-1 Phosphorylation at Threonine 770/772

The Journal of biological chemistry, 2014-02, Vol.289 (6), p.3148-3163

2014

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Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

Journal of visualized experiments, 2017-08 (126)

2017

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Receptor Tyrosine Kinase-Targeted Cancer Therapy

Molecular-Targeted Therapies for Epidermal Growth Factor Receptor and Its Resistance Mechanisms

Distinct Afatinib Resistance Mechanisms Identified in Lung Adenocarcinoma Harboring an EGFR Mutation

KRAS and EGFR Amplifications Mediate Resistance to Rociletinib and Osimertinib in Acquired Afatinib-Resistant NSCLC Harboring Exon 19 Deletion/T790M in EGFR

Blockade of EGFR Activation Promotes TNF-Induced Lung Epithelial Cell Apoptosis and Pulmonary Injury

Acquired Resistance Mechanisms to Combination Met-TKI/EGFR-TKI Exposure in Met-Amplified EGFR-TKI-Resistant Lung Adenocarcinoma Harboring an Activating EGFR Mutation

Lysophosphatidylcholine Activates Adipocyte Glucose Uptake and Lowers Blood Glucose Levels in Murine Models of Diabetes

Novel Anti-FOLR1 Antibody-Drug Conjugate MORAb-202 in Breast Cancer and Non-Small Cell Lung Cancer Cells

B lymphocyte-induced maturation protein 1 is a novel target gene of aryl hydrocarbon receptor

Silver Nanoscale Hexagonal Column Chips for Detecting Cell-free DNA and Circulating Nucleosomes in Cancer Patients

Functional Characterization of IL-17F as a Selective Neutrophil Attractant in Psoriasis

Up-regulation of Syndecan-4 contributes to TGF-β1-induced epithelial to mesenchymal transition in lung adenocarcinoma A549 cells

Activation of Proteinase-Activated Receptor 2 Stimulates Soluble Vascular Endothelial Growth Factor Receptor 1 Release via Epidermal Growth Factor Receptor Transactivation in Endothelial Cells

Distinct Mechanisms of Receptor and Nonreceptor Tyrosine Kinase Activation by Reactive Oxygen Species in Vascular Smooth Muscle Cells: Role of Metalloprotease and Protein Kinase C-δ

Induction of Differentiation in Normal Human Keratinocytes by Adenovirus-Mediated Introduction of the η and δ Isoforms of Protein Kinase C

Activation of Protein Kinase Cζ Induces Serine Phosphorylation of VAMP2 in the GLUT4 Compartment and Increases Glucose Transport in Skeletal Muscle

Novel Functions of the Phospholipase D2-Phox Homology Domain in Protein Kinase Cζ Activation

Protein kinase C eta (PKC eta): its involvement in keratinocyte differentiation

Abstract 2113: KRAS amplification mediates resistance to osimertinib in acquired afatinib-resistant NSCLC harboring exon 19 deletion/T790M in EGFR

Role of CPI-17 in the regulation of endothelial cytoskeleton

Localization of phospholipase D1 to caveolin-enriched membrane via palmitoylation: implications for epidermal growth factor signaling

PKCη associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes

PKC δ mediates ionizing radiation-induced activation of c-Jun NH2-terminal kinase through MKK7 in human thyroid cells

Vascular Endothelial Tight Junctions and Barrier Function Are Disrupted by 15(S)-Hydroxyeicosatetraenoic Acid Partly via Protein Kinase Cϵ-mediated Zona Occludens-1 Phosphorylation at Threonine 770/772

Establishing Dual Resistance to EGFR-TKI and MET-TKI in Lung Adenocarcinoma Cells In Vitro with a 2-step Dose-escalation Procedure

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