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Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway

Angewandte Chemie International Edition, 2020-09, Vol.59 (40), p.17548-17555

International ed. in English, 2020

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Targeted Inhibition of the NCOA1/STAT6 Protein–Protein Interaction

Journal of the American Chemical Society, 2017-11, Vol.139 (45), p.16056-16059

2017

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Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (30), p.11007-11012

2014

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Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

Circulation (New York, N.Y.), 2006-09, Vol.114 (11), p.1159-1168

2006

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Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy

Journal of the American Heart Association, 2013-04, Vol.2 (2), p.e000016-e000016

2013

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Calcineurin Is Necessary for the Maintenance but Not Embryonic Development of Slow Muscle Fibers

Molecular and Cellular Biology, 2005-08, Vol.25 (15), p.6629-6638

2005

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A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

Angewandte Chemie International Edition, 2016-01, Vol.55 (2), p.602-606

International ed. in English, 2016

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Bridged α-helix mimetic small molecules

Chemical communications (Cambridge, England), 2019-10, Vol.55 (88), p.13311-13314

2019

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Novel Pyrrolopyrimidine-Based α-Helix Mimetics: Cell-Permeable Inhibitors of Protein−Protein Interactions

Journal of the American Chemical Society, 2011-02, Vol.133 (4), p.676-679

2011

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Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis

EMBO reports, 2018-12, Vol.19 (12), p.n/a

2018

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Reductively degradable polyester-based block copolymers prepared by facile polycondensation and ATRP: synthesis, degradation, and aqueous micellization

Soft matter, 2011-01, Vol.7 (16), p.7441-7452

2011

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Converting One-Face α‑Helix Mimetics into Amphiphilic α‑Helix Mimetics as Potent Inhibitors of Protein–Protein Interactions

ACS combinatorial science, 2016-01, Vol.18 (1), p.36-42

2016

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Amot130 Adapts Atrophin-1 Interacting Protein 4 to Inhibit Yes-associated Protein Signaling and Cell Growth

The Journal of biological chemistry, 2013-05, Vol.288 (21), p.15181-15193

2013

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Design, Solid-Phase Synthesis, and Evaluation of a Phenyl-Piperazine-Triazine Scaffold as α‑Helix Mimetics

ACS combinatorial science, 2014-12, Vol.16 (12), p.695-701

2014

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The CCAAT/Enhancer Binding Protein β (C/EBPβ) Cooperates with NFAT to Control Expression of the Calcineurin Regulatory Protein RCAN1–4

The Journal of biological chemistry, 2010-05, Vol.285 (22), p.16623-16631

2010

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Sustained Hemodynamic Stress Disrupts Normal Circadian Rhythms in Calcineurin-Dependent Signaling and Protein Phosphorylation in the Heart

Circulation research, 2011-02, Vol.108 (4), p.437-445

2011

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Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated [alpha]-synuclein

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (30), p.11007

2014

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Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway

Angewandte Chemie, 2020-09, Vol.132 (40), p.17701-17708

2020

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A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin κ Locus

Immunity (Cambridge, Mass.), 2006-04, Vol.24 (4), p.405-415

2006

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A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

Angewandte Chemie, 2016-01, Vol.128 (2), p.612-616

2016

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Abstract 3442: Normal Circadian Rhythms In Calcineurin-dependent Signaling And Protein Phosphorylation Are Disrupted In Heart Failure

Circulation (New York, N.Y.), 2008-10, Vol.118 (suppl_18)

2008

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A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin [kappa] Locus

Immunity (Cambridge, Mass.), 2006-04, Vol.24 (4), p.405-415

2006

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Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombe

Nucleic acids research, 2002-09, Vol.30 (18), p.4022-4031

2002

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Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIα gene promoter

Biochemical journal, 1999-12, Vol.344 (2), p.367-374

1999

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Isolation and identification of Fur binding genes in Escherichia coli

Molecules and cells, 1999-10, Vol.9 (5), p.517-525

1999

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Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway

Targeted Inhibition of the NCOA1/STAT6 Protein–Protein Interaction

Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated α-synuclein

Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy

Calcineurin Is Necessary for the Maintenance but Not Embryonic Development of Slow Muscle Fibers

A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

Bridged α-helix mimetic small molecules

Novel Pyrrolopyrimidine-Based α-Helix Mimetics: Cell-Permeable Inhibitors of Protein−Protein Interactions

Regulator of Calcineurin 1 helps coordinate whole‐body metabolism and thermogenesis

Reductively degradable polyester-based block copolymers prepared by facile polycondensation and ATRP: synthesis, degradation, and aqueous micellization

Converting One-Face α‑Helix Mimetics into Amphiphilic α‑Helix Mimetics as Potent Inhibitors of Protein–Protein Interactions

Amot130 Adapts Atrophin-1 Interacting Protein 4 to Inhibit Yes-associated Protein Signaling and Cell Growth

Design, Solid-Phase Synthesis, and Evaluation of a Phenyl-Piperazine-Triazine Scaffold as α‑Helix Mimetics

The CCAAT/Enhancer Binding Protein β (C/EBPβ) Cooperates with NFAT to Control Expression of the Calcineurin Regulatory Protein RCAN1–4

Sustained Hemodynamic Stress Disrupts Normal Circadian Rhythms in Calcineurin-Dependent Signaling and Protein Phosphorylation in the Heart

Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated [alpha]-synuclein

Targeted Degradation of Transcription Coactivator SRC‐1 through the N‐Degron Pathway

A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin κ Locus

A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

Abstract 3442: Normal Circadian Rhythms In Calcineurin-dependent Signaling And Protein Phosphorylation Are Disrupted In Heart Failure

A Recombination Silencer that Specifies Heterochromatin Positioning and Ikaros Association in the Immunoglobulin [kappa] Locus

Topoisomerase III is required for accurate DNA replication and chromosome segregation in Schizosaccharomyces pombe

Sp1 mediates cell proliferation-dependent regulation of rat DNA topoisomerase IIα gene promoter

Isolation and identification of Fur binding genes in Escherichia coli

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