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Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

Journal of medicinal chemistry, 2006-06, Vol.49 (12), p.3719-3742

2006

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Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3515-3527

2007

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Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of N-Aryl Cinnamides

Journal of medicinal chemistry, 2005-01, Vol.48 (1), p.71-90

2005

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Preparation of chiral cyanohydrins by an oxynitrilase-mediated transcyanation

Journal of the American Chemical Society, 1991-08, Vol.113 (18), p.6992-6996

1991

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Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of trans-Cinnamides

Journal of medicinal chemistry, 2007-07, Vol.50 (15), p.3497-3514

2007

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Trisubstituted pyrimidines as transient receptor potential vanilloid 1 (TRPV1) antagonists with improved solubility

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6539-6545

2007

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Deoxygenated inositol 1,4,5-trisphosphate analogs and their interaction with metabolic enzymes. (1R,2R,4R)-Cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor

Journal of medicinal chemistry, 1993-10, Vol.36 (20), p.3035-3038

1993

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Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1 H -benzimidazoles

Journal of medicinal chemistry, 2006-06, Vol.49 (12), p.3719-3742

2006

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1D-myo-inositol 1,4,5-trisphosphate and 1D-myo-inositol 1,3,4,5-tetrakisphosphate analogues modified at C-3; synthesis of 1D-3-C-(trifluoromethyl)-myo-inositol 1,4,5-trisphosphate and 1L-chiro-insitol 1,2,3,5-tetrakisphosphate from L-quebrachitol

Journal of the Chemical Society. Chemical communications, 1994 (5), p.599

1994

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Synthesis of 1H,2,3-Triazoles from 2-Substituted Cyclododecanones and Phenyl Azide

Helvetica chimica acta, 1991-06, Vol.74 (4), p.899-903

1991

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Synthesis of macrocyclic enaminolactams by ring expansion reaction of 2-oxocyclododecane-1-carbonitrile with diarylcarbodiimides

Tetrahedron, 1996-03, Vol.52 (12), p.4363-4376

1996

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Probing the D-1,4,5-IP3/D-1,3,4,5-IP4 functional interface. Synthesis and pharmacology of novel D-3-modified myo-inositol trisphosphate analogues

Journal of the Chemical Society. Chemical communications, 1994 (11), p.1301-1302

1994

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Synthese von Makrocyclen durch Ringerweiterung von 14gliedrigen cyclischen Imiden

Helvetica chimica acta, 1992-02, Vol.75 (1), p.62-68

1992

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Glycine transport inhibitors: A new class of antipsychotics?

Schizophrenia research, 1997, Vol.24 (1), p.211-211

1997

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Cycloalkylations of N-(ω-Halogenoalkyl)-substituted Macrocyclic Imides

Helvetica chimica acta, 1990-03, Vol.73 (2), p.272-276

1990

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Synthesis of macrocyclic imides by one-step ring enlargement

Helvetica chimica acta, 1989-11, Vol.72 (7), p.1522-1526

1989

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Palladium-Catalyzed Synthesis of 2-Allyl-2-nitrocycloalkanones

Synthesis (Stuttgart), 1985, Vol.1985 (6/7), p.645-647

1985

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One-Pot Synthesis of 5,6-Dihydro-8 H -dibenzo[ a,g ]quinolizine-8-ones and Related Isoquinolines; A New Synthesis of Xylopinine

Synthesis (Stuttgart), 1980-10, Vol.1980 (10), p.845-847

1980

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Cyclopentenone Annulation of 2-Oxocycloalkane-1-carbonitriles

Helvetica chimica acta, 1987-08, Vol.70 (5), p.1393-1399

1987

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A Convenient Synthetic Route to 4-Aryl-1,4-dihydro-3(2H)-isoquinolinones

Synthesis (Stuttgart), 1987, Vol.1987 (7), p.637-638

1987

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Synthesis of Gossypol Analogues

Helvetica chimica acta, 1989-03, Vol.72 (2), p.353-360

1989

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One-Pot Synthesis of 5,6-Dihydro-8H-dibenzo[a,g]quinolizine-8-ones and Related Isoquinolines; A New Synthesis of Xylopinine

Synthesis (Stuttgart), 1980, Vol.1980 (10), p.845-847

1980

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Synthesis of 5,7,11 b,12-tetrahydro-isoindolo[2,1-b]isoquinolinium methiodides and theirStevens rearrangement

Monatshefte für Chemie, 1982-08, Vol.113 (8-9), p.993-998

1982

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Synthesis of 8H-Dibenzo[a,g]quinolizin-8-ones from Homophthalic Anhydrides and 1-Chloroisoquinolines or Isoquinoline N-Oxides. A New Synthesis of Caseadine

Heterocycles, 1982, Vol.19 (6), p.1069

1982

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Carbohydrates. Synthetic Methods and Applications in Medicinal Chemistry. Herausgegeben von H. Ogura, A. Hasegawa und T. Suami. VCH Verlagsgesellschaft, Weinheim/VCH Publishers, New York/Kodansha Ltd., Tokio, 1992. XIII, 406 S., geb. 208.00 DM. - ISBN 3-527-29012-5/1-56081-701-1/4-06-205807-3

Angewandte Chemie, 1994, Vol.106 (6), p.733-733

1994

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Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1H-benzimidazoles

Novel Vanilloid Receptor-1 Antagonists: 2. Structure−Activity Relationships of 4-Oxopyrimidines Leading to the Selection of a Clinical Candidate

Discovery of Potent, Orally Available Vanilloid Receptor-1 Antagonists. Structure−Activity Relationship of N-Aryl Cinnamides

Preparation of chiral cyanohydrins by an oxynitrilase-mediated transcyanation

Novel Vanilloid Receptor-1 Antagonists: 1. Conformationally Restricted Analogues of trans-Cinnamides

Trisubstituted pyrimidines as transient receptor potential vanilloid 1 (TRPV1) antagonists with improved solubility

Deoxygenated inositol 1,4,5-trisphosphate analogs and their interaction with metabolic enzymes. (1R,2R,4R)-Cyclohexane-1,2,4-tris(methylenesulfonate): a potent selective 5-phosphatase inhibitor

Design of Potent, Orally Available Antagonists of the Transient Receptor Potential Vanilloid 1. Structure−Activity Relationships of 2-Piperazin-1-yl-1 H -benzimidazoles

1D-myo-inositol 1,4,5-trisphosphate and 1D-myo-inositol 1,3,4,5-tetrakisphosphate analogues modified at C-3; synthesis of 1D-3-C-(trifluoromethyl)-myo-inositol 1,4,5-trisphosphate and 1L-chiro-insitol 1,2,3,5-tetrakisphosphate from L-quebrachitol

Synthesis of 1H,2,3-Triazoles from 2-Substituted Cyclododecanones and Phenyl Azide

Synthesis of macrocyclic enaminolactams by ring expansion reaction of 2-oxocyclododecane-1-carbonitrile with diarylcarbodiimides

Probing the D-1,4,5-IP3/D-1,3,4,5-IP4 functional interface. Synthesis and pharmacology of novel D-3-modified myo-inositol trisphosphate analogues

Synthese von Makrocyclen durch Ringerweiterung von 14gliedrigen cyclischen Imiden

Glycine transport inhibitors: A new class of antipsychotics?

Cycloalkylations of N-(ω-Halogenoalkyl)-substituted Macrocyclic Imides

Synthesis of macrocyclic imides by one-step ring enlargement

Palladium-Catalyzed Synthesis of 2-Allyl-2-nitrocycloalkanones

One-Pot Synthesis of 5,6-Dihydro-8 H -dibenzo[ a,g ]quinolizine-8-ones and Related Isoquinolines; A New Synthesis of Xylopinine

Cyclopentenone Annulation of 2-Oxocycloalkane-1-carbonitriles

A Convenient Synthetic Route to 4-Aryl-1,4-dihydro-3(2H)-isoquinolinones

Synthesis of Gossypol Analogues

One-Pot Synthesis of 5,6-Dihydro-8H-dibenzo[a,g]quinolizine-8-ones and Related Isoquinolines; A New Synthesis of Xylopinine

Synthesis of 5,7,11 b,12-tetrahydro-isoindolo[2,1-b]isoquinolinium methiodides and theirStevens rearrangement

Synthesis of 8H-Dibenzo[a,g]quinolizin-8-ones from Homophthalic Anhydrides and 1-Chloroisoquinolines or Isoquinoline N-Oxides. A New Synthesis of Caseadine

Carbohydrates. Synthetic Methods and Applications in Medicinal Chemistry. Herausgegeben von H. Ogura, A. Hasegawa und T. Suami. VCH Verlagsgesellschaft, Weinheim/VCH Publishers, New York/Kodansha Ltd., Tokio, 1992. XIII, 406 S., geb. 208.00 DM. - ISBN 3-527-29012-5/1-56081-701-1/4-06-205807-3

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