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Gatekeeping strategies for clinical trials that do not require all primary effects to be significant

Statistics in medicine, 2003-08, Vol.22 (15), p.2387-2400

2003

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Selective seratonin 1F (5-HT 1F) receptor agonist LY334370 for acute migraine: a randomised controlled trial

The Lancet (British edition), 2001-10, Vol.358 (9289), p.1230-1234

2001

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A Bayesian credible subgroups approach to identifying patient subgroups with positive treatment effects

Biometrics, 2016-12, Vol.72 (4), p.1026-1036

2016

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Lanepitant, an NK-1 Antagonist, in Migraine Prevention

Cephalalgia, 2001-03, Vol.21 (2), p.102-106

2001

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Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

Archives of neurology (Chicago), 1997-04, Vol.54 (4), p.465

1997

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Brain proton magnetic resonance spectroscopy (1H-MRS) in Alzheimer's disease: changes after treatment with xanomeline, an M1 selective cholinergic agonist

The American journal of psychiatry, 1997-10, Vol.154 (10), p.1459-1461

1997

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The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease

Alzheimer disease and associated disorders, 1997, Vol.11, p.S16-S22

1997

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Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

The EMBO journal, 2006-03, Vol.25 (6), p.1396-1405

2006

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Efficacy of xanomeline in Alzheimer disease : Cognitive improvement measured using the computerized neuropsychological test battery (CNTB)

Alzheimer disease and associated disorders, 1998-12, Vol.12 (4), p.304-312

1998

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An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex

Journal of molecular biology, 1998-11, Vol.283 (5), p.907-912

1998

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Efficacy Definitions for Migraine Studies

Cephalalgia, 1999-05, Vol.19 (4), p.248-249

1999

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Determination of pregnancy outcome risk rates after exposure to an intervention

Clinical pharmacology and therapeutics, 2001-01, Vol.69 (1), p.7-13

2001

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Nizatidine versus placebo in gastroesophageal reflux disease : a 12-week, multicenter, randomized, double-blind study

The American journal of gastroenterology, 1991-12, Vol.86 (12), p.1735-1742

1991

Volltextzugriff (PDF)

Lanepitant, An NK-1 Antagonist, in Migraine Prophylaxis

Clinical pharmacology and therapeutics, 1999-02, Vol.65 (2), p.129-129

1999

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Continuous Infusions of Nizatidine Are Safe and Effective in the Treatment of Intensive Care Unit Patients at Risk for Stress Gastritis

Scandinavian journal of gastroenterology, 1994, Vol.29 (S206), p.29-34

1994

Volltextzugriff (PDF)

RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations

Protein engineering, 1997-03, Vol.10 (3), p.273-278

1997

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Dose-effect and concentration-effect relationships of pinacidil and hydrochlorothiazide in hypertension

Clinical pharmacology and therapeutics, 1989-08, Vol.46 (2), p.208-218

1989

Volltextzugriff (PDF)

Investigating Drug-Induced QT and QTc Prolongation in the Clinic: A Review of Statistical Design and Analysis Considerations: Report from the Pharmaceutical Research and Manufacturers of America QT Statistics Expert Team

Therapeutic innovation & regulatory science, 2005-07, Vol.39 (3), p.243-265

Patterson, Scott D.

2005

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Relationship between steady-state plasma nizatidine concentrations and inhibition of basal and stimulated gastric acid secretion

Clinical pharmacology and therapeutics, 1990-04, Vol.47 (4), p.499-503

1990

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Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A

Acta crystallographica. Section D, Biological crystallography., 1999-03, Vol.55 (3), p.671-676

1999

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Healing and recurrence of active duodenal ulcer with nizatidine

Clinical pharmacology and therapeutics, 1989-09, Vol.46 (3), p.310-316

1989

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Nizatidine versus placebo in gastroesophageal reflux disease : a six-week, multicenter, randomized, double-blind comparison

Digestive diseases and sciences, 1992-06, Vol.37 (6), p.865-874

1992

Volltextzugriff (PDF)

Effect of nizatidine and cimetidine on betazole-stimulated gastric secretion of normal subjects: comparison of effects on acid, water, and pepsin

The American journal of gastroenterology, 1988, Vol.83 (1), p.32-36

1988

Volltextzugriff (PDF)

Nizatidine versus placebo in active benign gastric ulcer disease: An eight-week, multicenter, randomized, double-blind comparison

Clinical pharmacology and therapeutics, 1992-09, Vol.52 (3), p.307-313

1992

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Intravenous nizatidine kinetics and acid suppression

Clinical pharmacology and therapeutics, 1985-02, Vol.37 (2), p.162-165

1985

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Gatekeeping strategies for clinical trials that do not require all primary effects to be significant

Selective seratonin 1F (5-HT 1F) receptor agonist LY334370 for acute migraine: a randomised controlled trial

A Bayesian credible subgroups approach to identifying patient subgroups with positive treatment effects

Lanepitant, an NK-1 Antagonist, in Migraine Prevention

Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease

Brain proton magnetic resonance spectroscopy (1H-MRS) in Alzheimer's disease: changes after treatment with xanomeline, an M1 selective cholinergic agonist

The selective muscarinic agonist xanomeline improves both the cognitive deficits and behavioral symptoms of Alzheimer disease

Structure of a flavonoid glucosyltransferase reveals the basis for plant natural product modification

Efficacy of xanomeline in Alzheimer disease : Cognitive improvement measured using the computerized neuropsychological test battery (CNTB)

An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex

Efficacy Definitions for Migraine Studies

Determination of pregnancy outcome risk rates after exposure to an intervention

Nizatidine versus placebo in gastroesophageal reflux disease : a 12-week, multicenter, randomized, double-blind study

Lanepitant, An NK-1 Antagonist, in Migraine Prophylaxis

Continuous Infusions of Nizatidine Are Safe and Effective in the Treatment of Intensive Care Unit Patients at Risk for Stress Gastritis

RNA cleavage without hydrolysis. Splitting the catalytic activities of binase with Asn101 and Thr101 mutations

Dose-effect and concentration-effect relationships of pinacidil and hydrochlorothiazide in hypertension

Investigating Drug-Induced QT and QTc Prolongation in the Clinic: A Review of Statistical Design and Analysis Considerations: Report from the Pharmaceutical Research and Manufacturers of America QT Statistics Expert Team

Relationship between steady-state plasma nizatidine concentrations and inhibition of basal and stimulated gastric acid secretion

Crystallization of the regulatory and effector domains of the key sporulation response regulator Spo0A

Healing and recurrence of active duodenal ulcer with nizatidine

Nizatidine versus placebo in gastroesophageal reflux disease : a six-week, multicenter, randomized, double-blind comparison

Effect of nizatidine and cimetidine on betazole-stimulated gastric secretion of normal subjects: comparison of effects on acid, water, and pepsin

Nizatidine versus placebo in active benign gastric ulcer disease: An eight-week, multicenter, randomized, double-blind comparison

Intravenous nizatidine kinetics and acid suppression

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